Your legs are soothed, toned and lighter.

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For warnings, precautions for use and contraindications, please consult the instructions for use.


Antistax circulatory comfort is a food supplement based on bio-flavonoids 100% of natural origin, contained in a standardized extract of red vine leaves: AS 195. It is guaranteed: this extract which contains a constant quality of quercetin , isoquercitrine and kaempferol , is effective for the circulatory comfort of your legs .

Description of Antistax

Your legs are soothed, toned and lighter.

In case of chronic pathology, it is possible to combine this treatment with L28 LEHNING oral drops , homeopathic treatment for venous circulation disorders (varicose veins, varicose ulcers, hemorrhoids).

Directions for use of Antistax

1 tablet per day, to be taken regularly for at least 2 to 3 weeks. If necessary: 2 tablets per day. Take before meals, with a little water, preferably in the morning.
For enhanced effectiveness, use the Freshness Gel or the Intense Antistax Freshness Spray.

Composition of Antistax

Standardized extract of red vine leaves (Vitis vinifera), stabilizer (microcrystalline cellulose), thickener (anhydrous calcium hydrogen phosphate), anti-caking agent (anhydrous colloidal silica), stabilizers (croscarmellose sodium, crospovidone), coating agent (hypromellose), anti-caking agent (magnesium stearate), coating agent (talc), coloring agent (red iron oxide), coating agent (glyceryl tristearate), coloring agent (titanium dioxide).

Quantity for 1 tablet / day Quantity for 2 tablets / day
Red vine leaves extract
(AS 195) 360 mg 720 mg
Of which total bio-flavonoids content (3%) 10.8 mg 21.6 mg.

Antistax precaution

  • Do not use as a substitute for a varied diet.
  • Respect the proposed daily dose.
  • Favor a healthy lifestyle.
  • Not recommended for children, adolescents, pregnant or lactating women.
  • Keep at temperature not exceeding 30 ° protected from moisture, in the original packaging. Do not remove from the blister before use.
  • Keep out of reach of children.
  • Consume preferably before the date written on the box.

Presentation of Antistax

3 boxes of 20 tablets

Learn more about the different pathologies of venous circulation .

  • Heaviness in the legs or calves is a particular feeling of heaviness in the legs, generally greater at the end of the day, in case of high heat, when standing or sitting for a long time, or when the calf is compressed in clothes or shoes that are too tight.
  • Phlebalgia is pain specific to a venous path and can result in stitches in the path of the veins.
  • Lower extremity cramps appear in 30% of venous diseases and are characterized by a lasting and abnormal contraction of a leg muscle, reflecting poor drainage of oxygen-depleted blood.
  • Impatience is a feeling of numbness defined as an urge to move your legs during prolonged stationary stations, forcing you to get up.

Drug warnings

Attention, the drug is not a product like the others. Read the package leaflet carefully before ordering. Keep medicines out of the reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Beware of incompatibilities on your current products.

  • Please inform your online pharmacist of the treatments in progress in order to identify any incompatibilities. The order validation form contains a personalized message field provided for this purpose.
  • Click here to find the package leaflet for this medication on the website of the National Agency for the Safety of Medicines and Health Products.
  • Pharmacovigilance: Declare an undesirable effect (s) linked to the use of a drug



Phytotherapy for vasculoprotective surgery

red vine

. Presentations . Composition . Indications . Warning . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon


ANTISTAX: tablet; box of 30.

ANTISTAX: tablet; box of 60.

Laboratory Boehringer Ingelheim France

p cp
Red vine, leaf extract 360 mg

This medicine contains a plant extract that has a protective effect on the blood vessels.
It is traditionally used in the symptomatic treatment of disorders related to poor venous circulation (heavy or painful legs, tension, calf cramps).
WARNING (Contents)
The treatment of venous insufficiency is based on specific measures such as the wearing of compression stockings.
Take a quick medical opinion if the swelling suddenly appeared, if it touches a single leg or the leg is red and hot locally.
This medicinal product contains an assumed safe plant during pregnancy or lactation. Nevertheless, as a precaution, do not use it without the advice of your pharmacist or doctor.
The tablets should be swallowed with a large glass of water before breakfast.

Usual dosage:

  • Adult: 1 or 2 tablets in the morning.
The recommended treatment duration is 3 months.
TIPS (summary)
Regular physical activity and elevation of the foot of the bed facilitate the venous and lymphatic circulation.
Uncommon: nausea, digestive disorders, rash with itching, urticaria.

GLOSSARY (summary)

venous insufficiency
Incapacity of the veins of the legs to bring the blood back to the heart.

The lymph, a colorless liquid that circulates in specific vessels and whose accumulation causes edema.

symptomatic treatment
Treatment that suppresses or alleviates the symptoms of a disease without addressing its cause.

Click here to find the record of this drug on the website of the National Agency for the Safety of Medicines and Health Products.

Pharmacovigilance : Report an adverse effect (s) related to the use of a drug


ANSM - Last updated: 20/04/2017

Name of the medicinal product

ANTISTAX 360 mg, coated tablet

Red vine extract


Please read this leaflet carefully before you start taking this medicine because it contains important information for you.

You should always take this medication exactly as prescribed in this leaflet or by your doctor or pharmacist.

· Keep this leaflet. You might need to read it again.

· Ask your pharmacist for advice or information.

· If you experience any of the side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. See section 4.

· You should contact your doctor if you do not feel any improvement

Do not use this medication for children.

What is in this leaflet?

1. What is ANTISTAX 360 mg, coated tablet and in which cases it is used?

2. What should be known before taking ANTISTAX 360 mg coated tablet?

3. How to take ANTISTAX 360 mg, coated tablet?

4. What are the possible side effects?

5. How to store ANTISTAX 360 mg coated tablet?

6. Package contents and other information.

1. WHAT IS ANTISTAX 360 mg, coated tablet AND WHAT IT IS USED FOR?

Herbal medicines.

A herbal medication indicated for the treatment of chronic venous insufficiency characterized by swelling of the legs, varicose veins, a feeling of heaviness, pain, fatigue, itching, tension and calf cramps.

2. BEFORE YOU TAKE ANTISTAX 360 mg, coated tablet?

Do not take ANTISTAX 360 mg, coated tablet:

· if you are allergic to the active substance or any of the other ingredients of this medicinal product mentioned in section 6;

Warnings and Precautions

Talk to your doctor or pharmacist before taking ANTISTAX 360 mg, coated tablet if:

- inflammation of the skin,

- thrombophlebitis (inflammation of a vein due to a blood clot) or subcutaneous induration (abnormal hardening under the skin),

- severe pain,

- sudden swelling in one or both legs, ulcers,

- ulcers,

- heart or kidney failure

- persistence of edema in both legs. This persistence may be due to other causes that need to be assessed by a physician.

In the event of an inadequate or unsatisfactory symptomatic response within two weeks, medical advice should be sought.

In the absence of adequate safety data, this medicinal product is not recommended for use in children and adolescents under 18 years of age.

Other medicines and ANTISTAX 360 mg, coated tablet

Inform your doctor if you are taking, have recently taken or may take any other medication.

ANTISTAX 360 mg, tablet coated with food

Not applicable.

Pregnancy, breast-feeding and fertility

The use of this medication during pregnancy or lactation should be avoided.

Ask your doctor or pharmacist for advice before taking any medicine.

Driving and using machines

Not applicable.

3. HOW TO TAKE ANTISTAX 360 mg, coated tablet?

Always take this medication exactly as prescribed by your doctor or pharmacist. Check with your doctor or pharmacist if in doubt.


Reserved for adults only.

1 tablet coated per day to take in the morning. The dosage can be increased up to 2 tablets per day.

Method and route of administration

Oral use.

Swallow the tablet with a large glass of water before breakfast.

Duration of treatment

The recommended treatment time is 12 weeks.

2 to 3 weeks of treatment may be necessary to observe beneficial effects.

Prolonged use is possible after consultation with your doctor. The duration of treatment is limited to 6 months.

If you take more ANTISTAX 360 mg, coated tablet than you should:

Consult your doctor or pharmacist. .

If you forget to take ANTISTAX 360 mg, coated tablet:

Do not take a double dose to make up for a missed dose.

If you stop taking ANTISTAX 360 mg, coated tablet:

Not applicable.


Like all medicines, this medication can cause side effects, although not everybody gets them.

The assessment of adverse reactions is based on the following frequencies:

Very common: affects more than 1 in 10 patients

Common: affects 1 to 10 patients out of 100

Uncommon: affects 1 to 10 of 1,000 patients

Rare: affects 1 to 10 patients out of 10,000

Very rare: affects less than 1 in 10,000 patients

Not known: can not be estimated from the available data.

Gastrointestinal disorders:

- Uncommon: Nausea, digestive disorders.

Skin and subcutaneous tissue disorders:

- Uncommon: generalized rash with itching, urticaria.

Immune system disorders:

- Uncommon: allergic reaction.

Nervous system disorders:

- Frequency not known: Headache.

Declaration of side effects

If you experience any side effects, talk to your doctor or pharmacist . This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Centers of Pharmacovigilance - Website:

By reporting adverse reactions, you are helping to provide more information about the safety of the drug.

5. HOW TO STORE ANTISTAX 360 mg, coated tablet?

Keep this medicine out of the reach and sight of children.

Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of that month.

Store at a temperature not exceeding 30 ° C. Store in the original package.

Do not remove from the blister pack before use.

Do not throw any medication into drains or household waste. Ask your pharmacist to remove any medications you are no longer using. These measures will help protect the environment.


What ANTISTAX 360 mg contains: coated tablet

· The active substance is:

Red vine ( Vitis vinifera L.) (leaf extract of) ........................................ ... 360.00mg

Extraction solvent: water

Drug Report / Excerpt: 4-6: 1

for a coated tablet

· The other components are:

Other components are hypromellose, glyceryl tristearate, titanium dioxide (E171), talc, red iron oxide (E 172), microcrystalline cellulose, croscarmellose sodium, anhydrous calcium hydrogen phosphate, crospovidone, anhydrous colloidal silica, magnesium stearate.

What is ANTISTAX 360 mg, coated tablet and contents of the pack

Coated tablet. Box of 20, 30, 40 or 60.

Marketing Authorization Holder




Marketing Authorization Operator







51100 REIMS

Names of the medicinal product in the Member States of the European Economic Area

Not applicable

The last date on which this leaflet was revised is:

[to be completed later by the holder]

<{MM / YYYY}> <{YYYY month}.>


Detailed information on this medicine is available on the ANSM website (France).

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