Endotélon 60 tablets Venous Circulation Disorders
Over-the-counter medication

Endotélon 60 tablets Venous Circulation Disorders

Brand : Serb Serb

Endotélon is an over-the-counter venotonic medication recommended for venous circulation disorders: heavy legs, pain, and uncomfortable sensations known as "restless legs" when lying down. Order it at a fair price at your local pharmacy.

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This product is an over-the-counter medication. Please consult the package insert before ordering online.
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For warnings, precautions, and contraindications, please refer to the Endotélon package insert.

What are the indications for the venotonic Endotélon?

Endotélonis an over-the-countervenotonicmedication that improves the tone of vein walls, and a vasculoprotective agent that increases the resistance of small blood vessels.

Endotélon is recommended forvenous circulation disorders:heavy legs, pain, and uncomfortable sensations known as “restless legs” when lying down. It is also recommended for the treatment of lymphatic edema in the armfollowing radiosurgical treatment of a breast tumor, as a supplement to physical therapies such as compression stockings.

Effective relief for heavy legs

Venous circulation disorders can make your legs feel heavy and uncomfortable. Fortunately, Endotelon is here to provide you with effective relief. This venotonic medication, available without a prescription, is specially formulated to treat symptoms such as heavy legs, pain, and unpleasant sensations—often called “restless legs”—that occur mainly at bedtime. Don’t let venous circulation problems disrupt your daily life. Choose Endotélon and rediscover light, comfortable legs.

With powerful antioxidant properties, grape seed extract is also beneficial for cardiovascular health. Grape seed extract also improves blood circulation, vision, and skin health. The extract derived from the tiny seeds of black grapes has become a highly sought-after nutritional supplement. It contains substances called oligomeric proanthocyanidins (OPCs), also known as procyanidins and formerly referred to as pycnogenols.

Targeted Action for Better Circulation

Endotélon works by strengthening the walls of blood vessels, which improves venous circulation and reduces unpleasant symptoms. Its special formula provides rapid relief from heavy legs and alleviates feelings of discomfort, helping you regain your sense of well-being. Trust Endotélon to boost your circulation and restore lightness to your legs.

Discover howGranions Veinomix, a specially formulated supplement, can help relieve discomfort associated with circulatory issues by clicking on“Improving Venous Comfort with Granions Veinomix and Hemorrhoid Treatment”to learn more.

Available in our online pharmacy

Your comfort is our priority. That’s why we offer Endotélon in our online pharmacy. You can purchase this vein-tonic medication with confidence, knowing that it provides effective relief from venous circulation problems. Don’t let unpleasant symptoms slow you down. Get Endotélon today and regain the well-being you deserve.

What is in Endotélon?

This venotonic medication contains a concentrated natural active ingredient:purified grape seed extract standardized to 150 mg of procyanidolic oligomers per enteric-coated tablet.

Inactive ingredients: microcrystalline cellulose, anhydrous colloidal silica, magnesium stearate, methacrylic acid/ethyl acrylate copolymer (1:1), sodium hydroxide, triethyl citrate, sucrose, gelatin, gum arabic, titanium dioxide (E 171), talc, yellow iron oxide (E 172), carnauba wax (powder).

Excipient with known effect: sucrose

Dosage—how should Endotélon be taken?

Oral use: 1 tablet in the morning and 1 tablet in the evening, 20 days per month.

Forarm lymphedema: 1 tablet in the morning and 1 tablet in the evening, taken continuously.

Grape seed may affect the body in various ways; here are the therapeutic benefits attributed to it:

  • It helps prevent certaincancers(particularly skin cancer) by fighting free radicals and reducing the harmful effects of UV rays on the skin.
  • They help maintaincognitive functionbecause they may limit the formation of brain plaques found, for example, in patients withAlzheimer’s disease.
  • Grape seeds have a beneficial effect on people with macular degeneration: they improveblood flow to the retina.

Learn more about variousvenous circulation disorders.

  • Heaviness in the legsor calves is a distinct sensation of weight in the legs, generally more pronounced at the end of the day, in hot weather, during prolonged standing or sitting, or when the calf is constricted by clothing or shoes that are too tight.
  • Phlebalgiarefers to pain specific to a particular venous pathway and can manifest as sharp, shooting pains along the course of the veins. 
  • Legcrampsoccur in 30% of cases of venous disease and are characterized by a prolonged, abnormal contraction of a leg muscle, indicating poor drainage of oxygen-depleted blood.
  • Restlesslegssyndromeinvolves sensations of numbness defined as an irresistible urge to move the legs during prolonged periods of inactivity, forcing the person to stand up.

Contraindications with Endotélon

Allergy to any of the ingredients (procyanidolic oligomers)

Not recommended during breastfeeding

Precautions

  • Read the package insert carefully.
  • Keep out of reach of children
  • This product is available without a prescription.

Packaging

Box of 60 gastro-resistant-coatedEndotélontablets

Summary of Product Characteristics (ANSM)

Medication Warnings

Please note: Endotélon is not like other medications. Read the Endotélon package insert carefully before ordering. Keep medications out of the reach of children. If symptoms persist, consult your doctor or pharmacist. Be aware of potential drug interactions with your current medications.

  • Please inform your online pharmacist of any current treatments to identify potential interactions. The order confirmation form includes a custom message field for this purpose.
  • Click here to view the Endotélon package insert on the website of the French National Agency for Medicines and Health Products Safety (ANSM).
  • Pharmacovigilance: Report one or more adverse effects related to the use of Endotélon

How long does it take to feel the effects of Endotélon?

The effects of Endotélon may vary from person to person, but generally, you may experience symptom relief within the first few days of taking it.

Can I take Endotélon with other medications?

It is recommended that you consult your doctor or pharmacist before taking Endotélon with other medications to avoid potential interactions.

Are there any side effects associated with using Endotélon?

Side effects from Endotélon are rare but may include headaches or mild gastrointestinal upset. If you experience persistent side effects, please consult a healthcare professional.

Is Endotélon suitable for pregnant or breastfeeding women?

It is recommended that you consult a healthcare professional before taking Endotélon during pregnancy or while breastfeeding to determine if it is appropriate for your specific situation.

Can I use Endotélon long-term?

It is recommended that you do not use Endotélon long-term without consulting a healthcare professional. If your symptoms persist, consult your doctor.

Pharmacovigilance Report an adverse drug reaction(s)

Download PDF leaflet

NOTICE

ANSM - Last updated: 27/04/2017

Name of the medicinal product

ENDOTELON 150 mg gastro-resistant coated tablet

Grape seed extract

framed

Read this leaflet carefully before you start taking this medicine. It contains important information for your treatment.

If you have any further questions, ask your doctor or pharmacist.

· Keep this leaflet, you may need to read it again.

· If you need more information and advice, ask your pharmacist.

· If symptoms worsen or persist, consult your doctor.

· If you notice any side effects not listed in this leaflet, or if you experience any of the effects listed as serious, please tell your doctor or pharmacist.

What is in this leaflet?

1. What is ENDOTELON and when is it used?

2. What information should be known before taking ENDOTELON?

3. How to take ENDOTELON?

4. What are the possible side effects?

5. How to store ENDOTELON?

6. Package contents and other information.

1. WHAT IS ENDOTELON AND IN WHAT CASES IS IT USED?

VASCULOPROTECTOR / MEDICAMENT ACTING ON CAPILLAIRES.

(C05CX: cardiovascular system).

This drug is a veinotonic ( it increases the tonicity of the venous walls ) and a vasculoprotector ( it increases the resistance of the small blood vessels ).

It is used for:

- Relieve symptoms due to venous circulation disorders (heavy legs, pain, painful sensations called "impatience" at bedtime).

- treat lymphatic edema of the arm (infiltration of lymph in the arm support tissue) to treat after a radiosurgical treatment of a breast tumor, in addition to physical treatments such as elastic restraints.

2. BEFORE YOU TAKE ENDOTELON?

If your doctor has told you about an intolerance to some sugars, contact your doctor before taking this medicine.

Do not take Endotelon

· if you are allergic to procyanidolic oligomers (grape seed compounds) or any of the other ingredients of this medication. You can find the list of components in section 6.

· If you are breast-feeding, unless your doctor tells you otherwise.

Take special care with ENDOTELON 150 mg, coated gastro-resistant tablet:

Special warnings

If you are taking Endotelon for venous or lymphatic circulation disorders, you should combine this treatment with a healthy lifestyle. It is important to follow the following recommendations to promote venous circulation:

· avoid exposing yourself to sunlight or heat,

· Avoid standing prolonged,

· avoid overweight

· make regular long walks,

· wear suitable stocking stockings.

Taking other medicines

If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Pregnancy

If you are pregnant, you should use this medicine only on the advice of your doctor.

If you discover that you are pregnant during treatment, consult your doctor as he alone can judge the need to continue.

Ask your doctor or pharmacist for advice before taking any medicine.

feeding

Treatment is not advisable if you are breastfeeding.

Ask your doctor or pharmacist for advice before taking any medicine.

Driving and using machines

Procyanidolic oligomers have no effect on the ability to drive and use machines.

Important information about some of the ingredients of this medication

This medicine contains a sugar (sucrose).

Its use is not recommended in patients with fructose intolerance, glucose-galactose malabsorption syndrome or sucrase / isomaltase deficiency (rare hereditary diseases).

 

3. HOW TO TAKE ENDOTELON?

Dosage

In vein-lymphatic insufficiency: 2 tablets per day, in discontinuous administration (20 days per month).

In the lymphoedema of the arm: 2 tablets per day, in continuous administration.

Administration mode

This medication is taken orally.

Frequency of Administration

Take your tablets preferably outside meals. You will distribute the daily dose: 1 tablet in the morning and 1 tablet in the evening.

Duration of treatment

IN ALL CASES, COMPLY WITH THE ORDER OF YOUR DOCTOR STRICTLY.

If you forget to take ENDOTELON:

Take your tablet as soon as possible and continue your treatment as normal.

Do not take a double dose to make up for the missed dose.

 

4. WHAT ARE POSSIBLE SIDE EFFECTS?

Like all medicines, Endotelon can cause side effects, although not everybody gets them.

· Undesirable effects rarely occur:

· Allergic symptoms: urticaria, rash with or without itching, photosensitivity (skin reaction when exposed to the sun), eczema. These effects are rare and disappear when treatment is discontinued.

· stomach upset, nausea, diarrhea.

· Undesirable effects very rarely occur:

· swelling of the face, lips, tongue and / or larynx resulting in difficulty breathing or swallowing,

· swelling of the hands and feet, severe itching of the skin.

· headache.

Declaration of side effects:

If you experience any side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Centers of Pharmacovigilance 

By reporting adverse reactions, you are helping to provide more information about the safety of the drug.

5. HOW TO STORE ENDOTELON?

Keep out of the reach and sight of children.

Do not use ENDOTELON 150 mg enteric coated tablets after the expiry date which is stated on the carton.

No special storage conditions.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist what to do with unused medications. These measures will help protect the environment.

6. PACKAGE CONTENTS AND OTHER INFORMATION

What ENDOTELON 150 mg contains, gastro-resistant coated tablet

The active substance is :

Grape (purified seed extract from) .......................................... ............................................... 150 mg

quantified as procyanidolic oligomers for a coated tablet.

The other components are :

Microcrystalline cellulose, anhydrous colloidal silica, magnesium stearate, methacrylic acid / ethyl acrylate copolymer, sodium hydroxide, triethyl citrate, sucrose, gelatin, gum arabic, titanium dioxide (E171), talc, yellow iron (E 172), carnauba wax.

What is ENDOTELON 150 mg Gastro-resistant coated tablets and contents of the pack

This medication is in the form of an enteric coated tablet.

Box of 20, 40 or 60 tablets. Not all pack sizes may be marketed.

Marketing Authorization Holder

CHEPLAPHARM Arzneimittel GmbH

Bahnhofstr. 1a

17498 MESEKENHAGEN

GERMANY

Marketing Authorization Operator

Cheplapharm France

105 rue Anatole France

92300 Levallois-Perret

la France

Maker

SANOFI WINTHROP INDUSTRIE

1 RUE DE LA VIERGE

AMBARES AND LAGRAVE

33565 CARBON BLANC CEDEX

or

SANOFI SPA

SS 17 KM22,

66019 SCOPPITO

ITALY

Names of the medicinal product in the Member States of the European Economic Area

Not applicable.

The last date on which this leaflet was revised is:

[to be completed later by the holder]

<{MM / YYYY}> <{YYYY month}.>

Other

Detailed information on this medicine is available on the ANSM website (France).

VIDAL OF THE FAMILY

Endotelon

Vasculoprotective and veinotonic

oligomers procyanidolic

. Presentations . Composition . Indications . Warning . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS (summary)

ENDOTELON 150 mg: Gastro - resistant tablet (yellow); box of 60.
-

Laboratory

COMPOSITION (summary)
p cp
Grape seeds, purified extract standardized in procyanidolic oligomers 150 mg
Sucrose +

INDICATIONS (summary)
It is a vascular protector and a veinotonic . It stimulates the circulation of blood in the veins and combats the alteration of capillary vessels .
It is used in the symptomatic treatment:
  • heavy legs, pain, impatience and other disorders related to poor venous or lymphatic circulation;
  • of the arm edema after surgical treatment and / or radiotherapy for breast cancer, usually in addition to lymphatic drainage.
WARNING (Contents)
This drug is insufficient to prevent the risk of phlebitis in patients bedridden or plastered.
The treatment of venous insufficiency is based on specific measures such as the wearing of compression stockings.
PREGNANCY AND BREAST-FEEDING (summary)
The effect of this medication during pregnancy or lactation is not well known. The assessment of the possible risk associated with its use is individual: ask your pharmacist or doctor for advice.
DIRECTIONS FOR USE AND DOSAGE (summary)
This medication should be taken with a glass of water apart from meals.

Usual dosage:

1 tablet at 150 mg, morning and evening.
TIPS (summary)
Regular physical activity and elevation of the foot of the bed facilitate the venous and lymphatic circulation.
POSSIBLE ADVERSE EFFECTS (summary)
Rarely: allergic reaction , nausea, diarrhea, stomach pain.
Exceptionally: headaches.


GLOSSARY (summary)


enteric
Qualifies certain tablets or capsules in which the active substance is protected from the acidity of the stomach.


impatience
Painful sensations in the legs. They manifest themselves, usually during bedtime, by a feeling of discomfort, an irrepressible need to move their legs.


venous insufficiency
Incapacity of the veins of the legs to bring the blood back to the heart.


lymphatic
The lymph, a colorless liquid that circulates in specific vessels and whose accumulation causes edema.


edema
Accumulation of water or lymph causing localized swelling.


phlebitis
Inflammation of a deep vein with formation of a blood clot, usually affecting the legs. The severity of the phlebitis is related to the possibility of displacement of the clot which can migrate to the heart and then obstruct an artery of the lungs (pulmonary embolism). A paraphlebite, or superficial phlebitis, is the inflammation of a superficial vein; it is much less worrying.


allergic reaction
Reaction due to hypersensitivity of the organism to a drug. Allergic reactions can take a wide variety of aspects: urticaria, angioedema, eczema, eruption of pimples resembling measles, etc. Anaphylactic shock is a generalized allergic reaction that causes discomfort due to a sudden drop in blood pressure.


symptomatic treatment
Treatment that suppresses or alleviates the symptoms of a disease without addressing its cause.


capillary vessels
Blood vessels thinner than hair (hence their name) that irrigate the cells.


vascular
Blood vessels: arteries and veins.


veinotonic
Refers to a drug that has the property of increasing the tone of the wall.

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