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Sinovial 2 ml: 2 ml pre-filled syringes for single use (steam sterilized water), ready to use, sterile disposable + Type 21G x 1 ½ needles (sterilized by ethylene oxide) box 3 + 3 syringes needles (ACL 3401094747517).

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Sinovial ® 2 ml sinovial ® MINI

Updated: Thursday, March 21, 2013.

Applications: viscoelastic Injectables
Forms, Presentations
Viscoelastic solution for intraarticular injection:
Sinovial 2 ml: 2 ml pre-filled syringes for single use (steam sterilized water), ready to use, sterile disposable + Type 21G x 1 ½ needles (sterilized by ethylene oxide) box 3 + 3 syringes needles (ACL 3401094747517).
Sinovial Mini: Prefilled syringes of 1 ml disposable (sterilized water vapor), ready to use, 1 box (ACL 3401099169826).
The contents of the syringe are sterile and non-pyrogenic.
Sodium hyaluronate (the sodium salt of hyaluronic acid) 0.8% highly purified (8 mg hyaluronic acid / 1 ml of physiological sodium chloride buffered), sodium chloride, sodium phosphate and water for injections injectables (qs 100%).
Sinovial is a hyaluronic acid physiological solution buffered with visco-elastic properties. Sinovial contains hyaluronic acid having a molecular weight between 800 and 1200 kDalton.
Sodium hyaluronate (hyaluronan *) consists of repeated disaccharide units made of N-acetylglucosamine and sodium glucuronate. It is an essential component of synovial fluid and gives it its visco-elastic properties.
Another name often used.
Sinovial 2 ml is indicated in cases of pain or decreased mobility for a restoration of physiological and rheological properties of osteoarthritic joints.
Sinovial Mini is suitable for viscosupplementation small joints: All joints of the wrist and hand, including the interphalangeal joints, intercarpal, metacarpophalangeal, carpometacarpal, radio-ulnar distal and radiocarpal joint, all joints of the foot and temporomandibular joint and tendon sheaths (eg in case of tenosynovitis of the flexor tendons or trigger finger).
Sinovial agent is a suitable replacement joint fluid. It restores the physiological and rheological conditions of the osteoarthritic joint. The therapeutic action based on the special properties of the hyaluronic acid. Hyaluronic acid Sinovial obtained by fermentation and chemically unmodified, is very well tolerated. Restoring the viscoelastic properties of synovial fluid, Sinovial reduces pain and restores joint mobility.
Is only in the synovial joints where it was injected; it has no systemic effect.
Instructions, Dosage
It is recommended to administer Sinovial 2 ml according to a regimen of three injections, 1 week apart.
It is recommended to administer Sinovial Mini on a regimen February-March treatments per year, with intervals of 4 to 6 months, depending on the doctor's advice.
Suck a possible joint effusion before injecting Sinovial. Do not use Sinovial if the package is opened, damaged or incomplete. Check the integrity of the packaging before use. Inject Sinovial at room temperature and strictly observing the rules of asepsis. Be particularly careful not to touch the opening of the syringe by removing the cap. Use needle provided (Sinovial 2 ml) or appropriately sized needle of 18-22 G (Sinovial Mini). To ensure a tight connection and prevent leakage during administration, securely fit the needle to the syringe connector.
Should not inject Sinovial in an infected or acutely inflamed joint, or in patients with skin disease or infection at the site of injection.
Intra-articular injection can only be made by a physician.
Do not use disinfectants quaternary ammonium salts such as benzalkonium chloride because it is a known incompatibility with hyaluronic acid.
The possible presence of an air bubble does not affect the characteristics of the product.
The injection site should be located in healthy skin. Only inject into the joint space. Do not inject intravascularly. Do not inject outside the joint space in the synovial tissue or joint capsule. An extra-articular infiltration Sinovial may cause local adverse effects. Do not use Sinovial in the presence of a significant effusion.
Do not re-sterilize. The syringe and needles are for single use only. Do not reuse to avoid any risk of contamination.
As with any invasive procedure at a joint, it is recommended the patient to refrain from physical exertion after articular injection and not resume normal activities after a few days.
Side effects:

Events associated, such as pain, a feeling of warmth, redness or swelling may occur at the injection site after using Sinovial.
Applying ice to the treated joint can relieve such events associated. These usually resolve in a short time.
The patient should inform the doctor about any side effect may occur later.
Storage conditions
Do not use beyond the date shown on the packaging.
Store at a temperature between 4 ° C and 25 ° C, away from any heat source.
Do not freeze.
Sinovial should be used immediately after opening and discarded after use.
Administrative Information
List Price:
Sinovial Mini:
€ 23.00 (no support ISL, can not be supplied on medical prescription).
EC 0373 (ISTISAN) marking.
Medical device, Class III.
Revision Date of record: June 2012.
JUNIPER Laboratories SA
ZI Les 3 Moulins. 280, rue de Goa
Park of Sophia-Antipolis
06901 Sophia-Antipolis
Tel: 04 92 91 15 60 Fax:. 04 92 91 15 30

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