HUMEX COLD DAY AND NIGHT URGO 12 + 4 is a medicine that contains a vasoconstrictor nasal decongestant (pseudiéphédrine), an analgesic (acetaminophen) and an antihistamine (chlorphenamine). Humex cold is indicated for the treatment of colds in adults and in adolescents over 15 years: from the stuffy nose sensation, clear runny nose, headache and / or fever.

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For warnings, precautions for use and cons-indications, see the instructions for use.


Humex cold is a medicine that contains a vasoconstrictor nasal decongestant (pseudiéphédrine), an analgesic (acetaminophen) and an antihistamine (chlorphenamine). It is indicated for the treatment of colds in adults and in adolescents over 15 years: from the stuffy nose sensation, clear runny nose, headache and / or fever.

Packaging: 12 tablets and 4 capsules Day Night

Composition for one tablet (for the day)   :

Paracetamol 500 mg + 60.0 mg of pseudoephedrine hydrochloride.

Excipients: microcrystalline cellulose, pregelatinized starch, croscarmellose sodium, magnesium stearate, povidone K 30.

Composition for a capsule   (for the night) :

Paracetamol 500 mg + 4.0 mg chlorpheniramine maleate.

Excipients: talc, croscarmellose sodium, sodium lauryl sulfate, colloidal anhydrous silica.
Composition of the capsule shell: erythrosine, indigo carmine, gelatin, titanium dioxide.

Dosage   :

Oral use.
For adults (from 15 years):
Day 1 tablet (white) in the morning, to renew if necessary for lunch and dinner.
Night 1 capsule (blue and white) at bedtime, with an interval of at least four hours between each dose; do not exceed the maximum dosage of 3 days and tablets Night capsule per 24 hours.

The maximum treatment duration is 4 days.

If you have the impression that the effect of this medicine is too strong or too weak, talk to your doctor or pharmacist.


Method and route of administration   :
Oral use.

Frequency and time at which the medicine should be administered   :

A renewed after 4 hours minimum.
In patients with severe renal insufficiency, the interval between doses of at least 8 hours.

Duration of treatment   :

The maximum treatment duration is 4 days. If symptoms do not give in, do not continue treatment and seek the advice of your doctor.

What to do in case of overdose   :

In case of accidental overdose or intoxication,   STOP THE TREATMENT AND CONSULT A DOCTOR IMMEDIATELY.

What to do in case the administration of one or more doses have been omitted   :

If you miss Humex Cold, tablet and capsule, do not take a double dose to make single-dose you forgot to take.

HUMEX COLD, tablet and capsule, MUST NOT BE USED in the following cases   :

  • Children under 15 years
  • If you have ever had a stroke.
  • In severe hypertension or unbalanced by the treatment.
  • When used in combination with vasoconstrictors drugs or with other drugs to relieve the nose they are administered orally or nasally
  • If history of allergy to the components of the product.
  • In case of serious heart disease (CHD), certain forms of glaucoma (increased pressure in the eye)
  • In case of difficulty urinating prostatic origin or another
  • In case of old or recent convulsions.
  • If you are treated with medications based nonselective MAOI (iproniazid) drugs prescribed in certain depressive states.
  • In case of severe liver disease due to the presence of paracetamol.
  • If you are breastfeeding.


Special warnings   :


  • It is imperative to adhere strictly to the dosage, duration of treatment 4 bear and cons-indications.
  • If overdose or taken by mistake too high a dose, contact your doctor immediately.

This medicine contains paracetamol. Other drugs contain. Do not mix, so as not to exceed the recommended daily dose.

  • During treatment, if acceleration feeling heart beat, palpitations, or increased occurrence of headache, onset of nausea, behavioral problems, stop treatment immediately and contact your doctor.

If you suffer   :

- High blood pressure,
- Cardiac diseases, hyperthyroidism (hyperfunction of the thyroid gland)
- Of personality disorders or diabetes,
- Renal insufficiency in order to adjust the dose,
- Predisposition to constipation, vertigo and urinary disorders,
- If you are taking medicines to treat migraine (including Alcaides drugs derived from ergot)
this drug should not be used until your doctor.

Precautions   :

  • If you have to undergo anesthesia, stop taking this medicine beforehand and prevent the anesthetist.

In case   : Purulent nasal discharge, fever persistence, no improvement after 4 days of treatment, CONSULT YOUR DOCTOR.

Drug interactions and other interactions   :

Kindly tell your doctor or pharmacist if you are taking or have recently taken any other medicines, it is a drug not prescribed.

This medicine contains a vasoconstrictor, the pesudoéphédrine, which should NOT INVOLVE other vasoconstrictor drugs such as bromocriptine, pergolide, lisuride, cabergoline, ergotamine, dilydroergotamine, methylphenidate or with other drugs to decongest the nose they are administered orally or nasally route (ephedrine, phenylpropanolamine, phenylephrine).

If in doubt, do not hesitate to ask your doctor or pharmacist.

Mention that you are taking this medicine if your doctor prescribes a dose of uric acid or sugar in the blood.

To avoid the adverse effects of an overdose, DO NOT INVOLVE WITHOUT MEDICAL ADVICE other medicines containing vasoconstrictor, paracetamol or antihistamines. If in doubt, do not hesitate to ask your doctor or pharmacist.

Abstain from alcoholic beverages during the treatment period.

Pregnancy - Lactation   :

Ask your doctor or pharmacist before taking any medicine.

Pregnancy   :
Taking this medicine is not recommended during pregnancy.

Lactation   :
Because of possible adverse reactions in nursing infants, taking this medicine is against-indicated if you are breastfeeding.

Effects on ability to drive and use machines   :

Attention is drawn, oamment ches vehicle drivers and machine operators, on the possibilities of sleepiness or alertness decline attached to the use of this medicine.
This is accentuated by the intake of alcoholic drinks or medications containing alcohol.

Sport   :
Sportsmen will be drawn to the fact that this specialty contains an active ingredient (peudoéphédrine) could produce a positive analytic result in doping controls.

Warnings on drugs

Warning, the drug is not a product like any other. Read the package leaflet before ordering. Do not leave medicines within reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Beware of incompatibilities on your current products.

Please tell your online pharmacist of current treatments to identify any incompatibilities. The order confirmation form contains a custom message field provided for this purpose.

Click here to find the manual of this drug on the website of the National Agency of Drug Safety and health products.

Pharmacovigilance Reporting an or effect (s) Adverse (s) bound (s) use of a medicament



Anti-rheumatic medication

paracetamol, pseudoephedrine, chlorphenamine

. Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon


HUMEX CHEMISINE: tablet and capsule; box of 12 tablets (white) and 4 capsules (white and blue).


p cp p gel
Paracetamol 500 mg 500 mg
Pseudoephedrine hydrochloride 60 mg
Chlorphenamine maleate 4 mg

This medication is in the form of tablets and capsules: the tablets contain paracetamol which has antipyretic and analgesic action and pseudoephedrine, a decongestant vasoconstrictor ; the capsules, intended to be taken at night, contain paracetamol and an antihistamine having a drying effect on nasal secretions.
It is used to relieve symptoms of colds: stuffy nose, runny nose, headache and / or fever.
This medication should not be used in the following cases:
WARNING (Contents)
Although it is available without a prescription, it contains a vasoconstrictor that can cause potentially serious cardiac or neurological adverse effects. Its use requires certain precautions, including compliance with doses and contraindications. Make sure you do not associate it with another medication containing a decongestant vasoconstrictor , especially nasally.
Decongestant vasoconstrictors can increase heart rate ( tachycardia ) and cause palpitations and nausea. If these adverse effects are too severe, treatment should be discontinued.
They may also be responsible for rare neurological complications ( convulsions , hallucinations, abnormal agitation), in particular in the case of excessive dosage . Respect the recommended dose.
It is advisable to take medical advice in the event of hyperthyroidism , heart disease, diabetes , psychic disorders, renal insufficiency and in the elderly, especially in the case of chronic constipation, tendency to dizziness or voltage.
Taking this medicine may cause acute glaucoma in susceptible persons: red, hard and painful eye, with blurred vision. An emergency consultation with an ophthalmologist is necessary.
Paracetamol is present alone or in combination with other substances in many medicines: make sure not to take several medicines containing paracetamol simultaneously, as a joint dose leads to a risk of overdosage, which can be toxic to the liver.
Avoid alcoholic beverages: increased risk of drowsiness.
This medication contains an antihistamine that can induce somnolence, sometimes intense in some people. This drowsiness can be increased by taking alcohol or other sedative drugs. Be sure to occasionally take the first shot that you bear it well, before driving or using a dangerous machine.
Sports: This medicinal product contains a substance considered as stimulant (phenylephrine, pseudoephedrine or synephrine), which is included in the 2004 monitoring program of the Ministry of Youth and Sports. It can be found in athletes' urine to detect any misuse.
This medication should not be combined with:
  • another oral decongestant vasoconstrictor containing phenylephrine, pseudoephedrine or methylphenidate or a nasal vasoconstrictor containing naphazoline, oxymetazoline, ephedrine or tuaminoheptane sulfate: risk of hypertensive crisis;
  • an antidepressant of the non-selective MAOI type ( MARSILID ): a period of at least 15 days must be respected between the taking of these 2 medicines.
It can interact with ergot derivatives used in Parkinson's disease (bromocriptine, pergolide, lisuride, cabergoline) or in migraine (ergotamine, dihydroergotamine, methysergide) or with selective AIMM (moclobemide).
If treated with an oral anticoagulant and paracetamol at maximum doses (4 g / day) for at least 4 days, increased monitoring of anticoagulant therapy may be required.
Pregnancy :
The effect of this medication during pregnancy is not well known. As a precaution, it is not recommended for use in pregnant women.

This drug passes into breast milk. It is contraindicated during breast-feeding.
Tablets and capsules should be swallowed with a glass of water, spacing outlets for at least 4 hours. In case of severe renal failure , it is necessary to space the catch for at least 8 hours.

Usual dosage:

  • Adult: 1 tablet in the morning, to be renewed possibly at noon and dinner, and 1 capsule in the evening at bedtime.
The duration of treatment should not exceed 4 days.
TIPS (summary)
This medicine has no anti-infectious effect. If the condition persists for more than a few days, consult your doctor.
Drowsiness or insomnia: the antihistamine is sedative while the vasoconstrictor may have an exciting effect. Depending on the person, one or the other of these effects can predominate.
Dry mouth, constipation, disturbances of accommodation , urine retention.
Orthostatic hypotension , disorders of balance, dizziness , tremors, agitation, confusion of ideas especially in the elderly.
Palpitations , anxiety, headache, sweating, nausea, vomiting.
Rarely: allergic reaction , abnormal blood count .

GLOSSARY (summary)

Brain injury due to haemorrhage or abrupt obstruction of an artery. Depending on the size of the lesion, the consequences are more or less serious: temporary discomfort, paralysis, coma.
Abbreviation: AVC.

"Focus" of the eye, allowing clear vision close up. Presbyopia is the most common disorder of accommodation; some drugs such as atropine may cause passenger accommodation problems.

adenoma of the prostate
Increase in the volume of the prostate gland located under the bladder of man. This increase in volume is benign, has no relationship to cancer, but can interfere with the passage of urine into the urethra through the gland.
Symptoms that suggest the presence of a prostate adenoma are:
  • difficulty urinating (slowness, weakness of the spray);
  • the need to get up several times at night to urinate;
  • urges to urinate imperiously and difficult to control.
Some drugs, especially atropinics, may have the undesirable effect of aggravating the discomfort and may lead to a total blockage of the bladder evacuation. They are therefore contraindicated or should be used cautiously in men with the symptoms described above.

General name designating a family of substances that have the property of being able to be mixed with water and fatty substances. The most common alcohol is ethyl alcohol (ethanol), but there are many other alcohols: methanol, butanol, etc. The degree of alcoholic solution corresponds to the volume of pure alcohol present in 100 ml of solution, knowing that 1 glass of wine or 1/2 of beer (25 cl) contains about 8 g of alcohol.
When alcohol is used as an antiseptic, an unpleasant odor denaturant is often added to prevent drinking. Contrary to a widespread belief, alcohol at 70o (or even 60o) is a better antiseptic than alcohol at 90o.

Medication that works against pain. Analgesics act either directly on the centers of pain in the brain or by blocking the transmission of pain to the brain.
Synonym: analgesic.

Affection healed or always in evolution. The antecedent may be personal or family. The background is the history of a person's health.

Medication that prevents blood from coagulating and therefore prevents clots from forming in the blood vessels.
Anticoagulants are used to treat or prevent phlebitis, pulmonary embolism, certain infarcts. They also prevent the formation of clots in the heart during rhythm disorders such as atrial fibrillation or in the case of an artificial heart valve.
There are two main types of anticoagulants:
  • oral anticoagulants, which block the action of vitamin K (antivitamin K, or AVK) and whose effectiveness is controlled by a blood test: INR (formerly TP);
  • injectable anticoagulants derived from heparin, the efficacy of which can be controlled by the blood assay of anti-Xa activity, Howell's Time (TH) or Cephalin Kaolin Time (TCK) depending on the products used. A regular dosage of blood platelets is necessary throughout the life of a heparin derivative.

Medication that works against depression. Some antidepressants are also used to combat obsessive-compulsive disorder, generalized anxiety, certain rebellious pain, enuresis, etc.
Depending on their mode of action and adverse effects, antidepressants are divided into different families: imipraminic antidepressants, serotonin reuptake inhibitors, selective or non-selective MAOIs. Finally, other antidepressants do not belong to any of these families, because they possess original properties.
The mode of action of antidepressants has two main aspects: the relief of moral suffering and the fight against inhibition which removes all will to action from the depressed. There may be a time lag between these two effects: moral suffering may persist, while the capacity for action reappears. During this short period, the risk of suicide in some depressed people can be increased. The physician takes it into account in its prescription (possible association with a tranquillizer) and it must imperatively be respected.

Medication that opposes different effects of histamine. Two main types exist: antihistamines type H1 (antiallergic) and antihistamines type H2 (gastric antiulcer). Some antihistamines of type H1 are sedative, others do not alter vigilance.

Medication used to lower the body temperature during bouts of fever.

Involuntary contractions limited to a few muscles or generalized to the whole body. They are due to excessive pain or stimulation of the brain: fever, poisoning, lack of oxygen, brain damage. Convulsions may be due to an epileptic seizure or high fever in young children.

A general term for diseases that result in the emission of abundant urine and intense thirst. The word diabetes, used alone, is generally related to diabetes mellitus, which corresponds to a disruption in the regulation of the body's sugars by insulin. It results in increased sugar (glucose) in the blood and its possible presence in the urine. There are two types of diabetes mellitus: Type 1 or insulin-dependent diabetes, which requires insulin injections, and type 2 or non-insulin dependent diabetes, which can initially be treated with oral antidiabetics.

Disease characterized by increased pressure of the fluids contained in the eye (intraocular hypertension).
This general term covers two totally different affections:
  • Open angle glaucoma or chronic glaucoma is the most common; it is generally symptom-free, detected by the measurement of intraocular tension in the ophthalmologist. It does not cause acute seizures, and treatment relies primarily on beta-blocking eye drops. People with open-angle glaucoma should not use cortisone derivatives without prior ophthalmologic advice.
  • Closed-angle glaucoma or acute glaucoma is more rare. Between seizures, intraocular tension is normal. But the inadvertent use of atropine medicines (especially eye drops) causes an acute crisis of intraocular hypertension which can permanently damage the retina in a few hours. It is an ophthalmological emergency that is recognized by a brutally red eye, horribly painful, hard as a glass ball, and whose vision becomes blurred.
The angle in question in these two affections is the irido-corneal angle. It is indeed between the iris and the cornea that is located the system of evacuation of the liquids of the eye. A slightly open (closed) angle exposes a total obstruction of the evacuation system. This obstruction can occur when the iris is opened to the maximum (mydriasis) under the effect of an atropinic drug: the iris then comes to be attached to the cornea.
Contraindications for atropine medicines are limited to those who have already had closed-angle glaucoma or have been detected by an ophthalmologist. Those who suffer from chronic open angle glaucoma are not affected by these contraindications.

high blood pressure
Excess blood pressure (tension) in the arteries. This pressure is provided by the heart and is expressed by two digits. It is maximal during contraction of the heart, or systole (first digit), and minimal during cardiac rest, or diastole (second digit). High blood pressure is characterized by a maximum (systolic) pressure greater than or equal to 16, or a minimum (diastolic) pressure greater than or equal to 9.5. Treatment is initiated when these numbers are exceeded or for lower blood pressure in some people with cardiovascular risk factors: heredity, smoking, diabetes, excess cholesterol. Permanent antihypertensive therapy reduces damage to the heart and blood vessels due to high blood pressure.

Excessive thyroid hormones, including heart failure, poor heat tolerance, weight loss and chronic fatigue.

Orthostatic hypotension
Reduced blood pressure when changing from elongated to standing. Due mostly to drugs, orthostatic hypotension results in dizziness with risk of fall, especially in the elderly. These disturbances can be prevented by avoiding sudden changes of position: sit for a few moments at the edge of the bed before standing, slowly rising from a seat, keeping a support before moving.
Wearing compression stockings, which prevents blood from flowing back to the legs while standing, is also used to treat orthostatic hypotension.

Abbreviation for mono-amine oxidase inhibitor. Family of drugs used in psychiatry and neurology (depression, Parkinson's disease). These drugs are divided into non-selective MAOIs, which are incompatible with many drugs and even certain foods, and selective MAOIs (A or B), for which these disadvantages are absent or limited.

coronary heart disease
Partial disability of the arteries of the heart (coronary arteries) to irrigate the heart muscle. Seizures of angina pectoris can occur, most often during an effort.

Hepatic insufficiency
Inability of the liver to perform its function, which is essentially the elimination of some waste, but also the synthesis of many biological substances essential to the body: albumin, cholesterol and coagulation factors (vitamin K, etc.).

renal failure
Inability of the kidneys to eliminate waste or medicinal substances. Advanced renal insufficiency does not necessarily result in a decrease in the amount of urine excreted. Only a blood test and creatinine dosage may reveal this disease.

blood count
The count measures the number of red blood cells (red blood cells), white blood cells (leukocytes) and platelets in the blood. The blood formula specifies the percentage of different white blood cells: neutrophils, eosinophils, basophils, lymphocytes, monocytes.
Abbreviation: NFS.

Abnormal perception of irregular heartbeat.

Chronic disease of the nervous system related to the alteration of certain brain cells and resulting in mobility disorders and sometimes tremors.

Quantity and distribution of the dose of a drug according to the age, weight and general condition of the patient.

allergic reaction
Reaction due to hypersensitivity of the organism to a drug. Allergic reactions can take a wide variety of aspects: urticaria, angioedema, eczema, eruption of pimples resembling measles, etc. Anaphylactic shock is a generalized allergic reaction that causes discomfort due to a sudden drop in blood pressure.

  • Quiets, calms down.
  • Medication belonging to different families: anxiolytics, hypnotics, analgesics, antitussives, antiepileptics, neuroleptics, etc. but also antidepressants, antihistamines H1, antihypertensives. A sedative can be responsible for drowsiness and increase the effects of alcohol.

Taking an excessive amount of a drug exposes you to an increase in the intensity of adverse effects, or even to the appearance of particular adverse effects.
This overdose may result from accidental or voluntary poisoning for suicide, so consult your local Poison Control Center (listed in the appendix to the book). However, in most cases, overdose is the result of an error in the understanding of the prescription, or the search for an increase in efficacy by exceeding the recommended dosage. Finally, untimely self-medication may lead to excessive absorption of the same substance contained in different drugs. Some drugs are particularly prone to this risk because they are (wrongly) considered to be harmless: vitamins A and D, aspirin, etc. Stopping or decreasing drug intake helps to remove the disorders associated with an overdose.

Accelerating the rhythm of the heartbeat. It may be due to fever, hyperthyroidism, heart disease, certain medications, and so on.

Medication that causes contraction of blood vessels, as opposed to vasodilator.

Symptom that can mean an impression of loss of balance (common sense) or, more strictly, a sense of rotation on oneself or the environment (medical sense).

Humex cheap in your medicine approved Ars

Humex is a drug contains a local antiseptic to fight infection and a local anesthetic to relieve pain.

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