Imodium Duo Diarrhée Aiguë 12 tablets combines loperamide and simeticone to rapidly soothe diarrhoea, reduce bloating and restore digestive comfort. This effective treatment works within 48 hours to help restore normal transit. Ideal for adults and adolescents aged 12 and over.
When acute diarrhea occurs, it's often accompanied by a host of unpleasant symptoms: abdominal cramps, bloating, flatulence and general digestive discomfort. Imodium Duo is specially designed to rapidly relieve these discomforts. It combines two complementary active ingredients - loperamide hydrochloride and simeticone - which work together to slow intestinal transit while reducing gas formation and abdominal bloating. Thanks to this dual action, it restores lasting digestive comfort and promotes a return to normal transit.
Loperamide is a powerful anti-diarrheal agent that acts directly on receptors in the intestinal wall. Its role is to slow colonic motility, enabling better absorption of water and electrolytes. This mechanism helps solidify stools and space out diarrheal episodes, providing rapid relief. At the same time, simeticone (or dimeticone) acts as an anti-flatulence agent: it reduces the tension of gas bubbles present in the digestive tract, encouraging their natural elimination and alleviating abdominal pain associated with aerophagia.
This synergy between loperamide and simeticone makes Imodium Duo particularly effective in episodes of acute diarrhea accompanied by bloating. In just a few doses, it helps restore intestinal comfort, reducing feelings of distension and the often annoying intestinal gurgling. Imodium Duo is therefore indicated in situations of temporary digestive disorders caused by viral infection, food intolerance, dietary changes or occasional stress.
Imodium Duo's formula targets not only stool frequency, but also the entire intestinal imbalance caused by diarrhea. Unlike other purely symptomatic treatments, its combined action enables a rapid, global approach. It helps restore functional intestinal flora and prevent dehydration linked to excessive fluid loss.
Imodium Duo is also appreciated for its tolerance and ease of use. In easy-to-swallow tablet form, it is suitable for adults and adolescents aged 12 and over. Used on an occasional basis, it is an effective daily ally for those who wish to regain digestive comfort without delay, while limiting the social inconvenience associated with diarrhea.
In short, Imodium Duo is a complete solution for soothing the intestine, reducing bloating and restoring harmonious digestion. It acts on both the functional cause of diarrhea and the symptoms that accompany it, guaranteeing a rapid return to intestinal well-being.
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Imodium Duo tablets should be swallowed whole with a full glass of water.
For adults over 18, the initial dose is 2 tablets, then 1 additional tablet after each liquid stool, up to a maximum of 4 tablets a day.
For adolescents aged 12 to 18, the recommended starting dose is 1 tablet, with a further tablet after each loose stool, up to a maximum of 4 tablets a day.
The maximum duration of treatment is 2 days. If symptoms persist beyond this period, it is essential to consult a doctor to rule out an infectious cause or dehydration.
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Precautions for use
Ingredients :
Loperamide Hydrochloride, Simeticone, Corn Starch, Microcrystalline Cellulose, Talc, Magnesium Stearate, Lactose Monohydrate, Anhydrous Colloidal Silica.
Nutritional values of Imodium Duo Diarrhée Aiguë 12 tablets
Packaging:
Box of 12 tablets. Available at the best price in our online pharmacy.
In the event of acute diarrhea, the first natural reflex is to rehydrate your body. Drink plenty of water, and opt for salted broths and oral rehydration solutions. To support your intestinal flora, consider introducing high-quality probiotics during and after treatment. They help restore intestinal balance and prevent recurrences.
On the dietary front, temporarily avoid raw fruit, dairy products, irritating fibers and spicy dishes. Instead, opt for rice, bananas, cooked carrots and grated apples, which soothe the intestinal mucosa. Activated vegetable charcoal can also be an excellent natural supplement for absorbing intestinal toxins and reducing gas.
Finally, as part of a naturopathic approach, take the time to rest your digestive system: stress and fatigue play a major role in the onset of intestinal disorders. Lemon balm, chamomile or peppermint herbal teas can help you relax and support more serene digestion.
Pharmacovigilance Report an adverse drug reaction(s)
ANSM - Updated on : 01/10/2025
Loperamide hydrochloride / Simeticone
Always take this medicine exactly as it is prescribed by your doctor, pharmacist or pharmacist.
- Keep this leaflet. You may need to read it again.
- Ask your pharmacist for any advice or information you may need.
- If you experience any of the side effects listed above, please tell your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. See section 4.
- You should contact your doctor if you do not feel any improvement or if you feel less well after 2 days.
What does this leaflet contain?
1. What is IMODIUMDUO, tablet and what is it used for?
2. What do I need to know before taking IMODIUMDUO, tablet?
3. How do I take IMODIUMDUO, tablet?
4. What are the possible side effects?
5. How do I keep IMODIUMDUO, tablet?
6. Package contents and other information.
1. WHAT IS IMODIUMDUO, tablet AND WHAT IS IT USED FOR?
The tablets contain two active ingredients:
- Loperamide hydrochloride, which helps to reduce diarrhoea by slowing intestinal transit. It also helps to increase the absorption of water and salts from the intestine.
- Simeticone, which acts by facilitating the coalescence of gas bubbles in the intestine that cause bloating and spasmodic pain.
IMODIUMDUO, tablet is used in adults and children aged 12 and over to treat acute diarrhoea with spasmodic pain, bloating and flatulence.
2. WHAT DO I HAVE TO KNOW BEFORE TAKING IMODIUMDUO, tablet?
Never take IMODIUMDUO, tablet:
- in children under 12 years of age,
- if you are allergic (hypersensitive) to loperamide, simeticone or any of the other ingredients of these tablets (see section 6),
- if you have a high fever (i.e. above 38°C) or if you have blood in your stools,
- if you suffer from chronic bowel or colon disease, particularly during acute flare-ups of ulcerative colitis,
- if your diarrhea occurs after taking antibiotics,
- if you suffer from constipation or abdominal swelling.
Warnings and precautions
Talk to your doctor or pharmacist before using IMODIUMDUO, tablet.
- IMODIUMDUO, tablet treats only the symptoms of diarrhea. In some cases, the cause of the diarrhea must be treated. If symptoms persist or worsen, contact your doctor. If you suffer from severe diarrhea, your body loses more fluids, sugars and salts than normal. You will need to rehydrate by drinking more fluids than usual. Ask your pharmacist for advice on rehydration solutions that compensate for fluid, sugar and salt losses.
- if you are a carrier of the AIDS virus and your belly swells, stop treatment immediately and contact your doctor.
- if you suffer from liver disease, check with your doctor before taking this medication. Some side effects may be more troublesome.
Only use this product for its intended purpose (see section 1) and never take more than the recommended dose (see section 3). Serious heart problems (symptoms may include rapid or irregular heartbeat) have been reported in patients who have taken too much loperamide, one of the active ingredients in IMODIUMDUO, tablet.
In the case of acute diarrhea, symptoms generally disappear within two days. If symptoms persist after this period, stop taking this medicine and contact your doctor.
Important information about certain ingredients of IMODIUMDUO, tablet :
This medicine contains less than 0.026 mg benzyl alcohol per tablet. Benzyl alcohol may cause allergic reactions. Ask your doctor or pharmacist for advice if you suffer from liver or kidney disease, or if you are pregnant or breast-feeding. Large quantities of benzyl alcohol may accumulate in your body and cause side effects (known as "metabolic acidosis").
This medicine contains less than 1 mmol (23 mg) of sodium per tablet, i.e. it is essentially "sodium-free".
This medicine contains less than 0.00044 mg alcohol (ethanol) per tablet. The small amount of alcohol contained in this medicine is unlikely to have any noticeable effect.
This medicine contains maltodextrin, which contains glucose. If your doctor has informed you that you are intolerant to certain sugars, contact him/her before taking this medicine.
Children
Children under 12 years of age should not take IMODIUMDUO, tablet.
Other medicines and IMODIUMDUO, tablet
Tell your doctor or pharmacist if you are taking, have recently taken or may take any other medicines, including:
- Quinidine (used to treat heart rhythm abnormalities and malaria)
- Litraconazole or ketoconazole (antifungal drugs)
- Gemfibrozil (used to treat high cholesterol)
- Ritonavir (used to treat HIV infection and AIDS)
- Desmopressin (used to limit thirst and urine production in patients suffering from diabetes insipidus)
If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist as IMODIUMDUO, tablet may interact with them.
Pregnancy
If you are pregnant, think you may be pregnant or are planning to become pregnant, ask your doctor or pharmacist for advice before taking this medicine.
Breast-feeding
IMODIUMDUO, tablet is not recommended if you are breast-feeding. Small amounts may be excreted in breast milk.
Driving and using machines
You may drive and operate machinery except if you feel tired, dizzy or sleepy.
3. HOW DO I TAKE IMODIUMDUO, tablet?
Always take IMODIUMDUO exactly as instructed in this leaflet, or as directed by your doctor or pharmacist. Check with your doctor or pharmacist if in doubt.
- Swallow the appropriate number of tablets whole with a glass of water.
- Oral use
- Do not take more tablets than the recommended dose.
Use in adults over 18
Start by taking 2 tablets for the first dose, then if diarrhea continues, take 1 additional tablet after each loose stool. Do not exceed 4 tablets per day. If symptoms persist after 2 days of treatment, discontinue and contact your doctor.
Use in children and adolescents 12 to 18 years of age
Start by taking 1 tablet for the first dose, then if diarrhea continues, take 1 additional tablet after each unformed stool. Do not exceed 4 tablets per day. If symptoms persist after 2 days of treatment, discontinue and contact your doctor.
Use in children and adolescents under 12 years of age
Do not give tablets to children under 12 years of age.
If you have taken more IMODIUMDUO, tablet than you should have :
If you have taken too much IMODIUMDUO, tablet, seek immediate medical or hospital advice. Symptoms may include: increased heart rate, irregular heartbeat, changes in your heart rhythm (these symptoms can be potentially serious and life-threatening), muscle stiffness, uncoordinated movements, drowsiness, difficulty urinating, respiratory distress, dry mouth or your pupils may narrow. You may experience abdominal pain, stomach ache or vomiting, or constipation.
Children react more strongly to high doses of IMODIUMDUO, tablet than adults. If a child takes too much or experiences any of the above symptoms, contact a doctor immediately.
If you forget to take IMODIUMDUO, tablet :
Take one tablet after your next loose bowel movement. Do not take a double dose to make up for the one you missed.
If you have any further questions about the use of this medicine, please ask your doctor or pharmacist.
4. WHAT ARE THE POSSIBLE SIDE EFFECTS?
If you experience any of the following symptoms, stop taking this medicine and tell your doctor immediately:
Allergic reaction including swelling of the face, tongue and throat, difficulty swallowing, unexplained sneezing, shortness of breath which may be accompanied by skin rash and urticaria.
Undetermined frequency (cannot be estimated on the basis of available data) : Pain in the upper abdomen, abdominal pain radiating to the back, tenderness of the abdomen to touch, fever, rapid pulse, nausea, vomiting, which may be symptoms of inflammation of the pancreas (acute pancreatitis).
If you experience any of the following symptoms, stop taking this medicine and tell your doctor:
- Difficulty in urinating,
- Severe abdominal pain, protrusion or swelling of the stomach, or fever, which may be caused by obstruction or dilatation of the bowel,
- Severe constipation.
Other effects that may occur :
Common adverse reactions (less than 1 in 10 but more than 1 in 100 people):
- Headache,
- Nausea,
- Taste alteration.
Uncommon adverse reactions (less than 1 in 100 but more than 1 in 1,000 people):
- Drowsiness,
- dizziness,
- Weakness,
- Constipation,
- Vomiting,
- Indigestion,
- Flatulence,
- Dry mouth,
- Rash.
Rare adverse reactions (less than 1 in 1,000 but more than 1 in 10,000 persons):
- Loss or reduction of consciousness,
- Narrowing of the pupils,
- Skin rash which may lead to severe blistering and peeling of the skin,
- Urticaria,
- Itching,
- Fatigue
- Muscle tension
- Uncoordinated movements
Reporting side effects
If you experience any side effects, please tell your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: Agence nationale de sécurité du médicament et des produits de santé (ANSM) and the network of Centres Régionaux de Pharmacovigilance - Website: https://signalement.social-sante.gouv.fr/
By reporting adverse reactions, you are helping to provide more information on drug safety.
5. HOW TO CONSERVE IMODIUMDUO, tablet?
Keep out of sight and reach of children.
Do not use this medicine after the expiration date indicated on the box and blister. The expiration date refers to the last day of that month.
No special storage precautions.
Do not dispose of any medicine with your household waste . Ask your pharmacist to dispose of any medicines you no longer use. These measures will help protect the environment.
6. CONTENTS AND OTHER INFORMATION
What IMODIUMDUO, tablet contains
- The active ingredients are :
Dimeticone in the form of simeticone .................................................................................. 125 mg
For one tablet.
- The other components are :
Calcium hydrogen phosphate, microcrystalline cellulose, acesulfame potassium, artificial vanilla flavor (containing propylene glycol, maltodextrin, ethanol and benzyl alcohol), sodium carboxymethyl starch (type A) and stearic acid.
What IMODIUMDUO, tablet is and what it contains
This medicine comes in the form of a white, capsule-shaped tablet, engraved " IMO " on one side and "2/125" on the other.
Boxes of 6, 8, 10, 12, 15, 16, 18 or 20 tablets.
Not all presentations may be marketed.
Marketing authorization holder
JOHNSON & JOHNSON SANTE BEAUTE FRANCE
43, RUE CAMILLE DESMOULINS
92130 ISSY LES MOULINEAUX
Marketing authorization holder
41 RUE CAMILLE DESMOULINS
91230 ISSY-LES-MOULINEAUX
JNTL CONSUMER HEALTH (France) SAS
DOMAINE DE MAIGREMONT
27100 VAL DE REUIL
Product names in member states of the European Economic Area
This product is authorized in the member states of the European Economic Area under the following names: In accordance with current regulations.
[To be completed later by the holder].
The last date on which this leaflet was revised was :
[to be completed later by the holder]
< {MM/YYYY}>< {month/YYYY}.>
Detailed information on this drug is available on the ANSM (France) website.
This medicine contains an antidiarrheal and a silicone digestive dressing. The antidiarrheal acts by slowing intestinal transit and reducing intestinal secretions.
It is used in the symptomatic treatment of acute diarrhea associated with abdominal bloating, as a complement to dietary measures.
Prices do not include dispensing fees.
| p cp | |
| Loperamide hydrochloride | 2 mg |
| Simeticone (expressed as dimeticone) | 125 mg |
This antidiarrheal can be obtained without a prescription. However, it should not be used without medical advice in cases of hepatic insufficiency or in HIV-infected people. If there is no improvement after 2 days of treatment, consult your doctor.
Treatment should be stopped as soon as stools start to form again, or if abdominal swelling occurs. Prolonged use of the drug may lead to severe constipation.
Loperamide may cause heart rhythm disorders in the event of overdosage; follow the dose and duration of treatment recommended by your pharmacist.
If you are going to drive or operate dangerous machinery, check beforehand that this medicine does not impair your alertness.
Studies currently available have not revealed any particular problems with the occasional use of this drug in pregnant women. Nevertheless, it is not recommended during pregnancy without medical advice.
This drug passes to a small extent into breast milk. However, its use is not recommended during breast-feeding.
Tablets should be swallowed with a glass of water.
Treatment duration should be limited to 2 days without medical advice.
Diarrhea can lead to dehydration, particularly in the elderly. This loss of water from the body must be compensated for with rehydration solutions or abundant beverages (salted broth, sweet drinks), as it can cause fatigue, malaise or confusion of ideas.
The diet to follow in the event of diarrhea is based on a light diet of :
banana, potato soup or purée;well-cooked pasta, rice or tapioca, rice cooking water;apple or quince compote, quince or blueberry jelly;sweet or savoury cookies.Avoid fruit juices and raw fruit, high-fiber vegetables, meat, eggs, dairy products and iced drinks.
Linked to the presence of loperamide :
Common (1-10% of people): constipation, nausea, flatulence, headache.
Uncommon (less than 1% of people): abdominal pain, vomiting, dry mouth, rash.
Rare (less than 0.1% of people): enlarged abdomen.
Undetermined frequency: drowsiness, fatigue, urticaria, itching, allergic reaction, severe constipation, acute pancreatitis.
Substance capable of blocking the multiplication of certain bacteria or killing them. The spectrum of an antibiotic is the set of bacteria on which the product is usually active. Unlike bacteria, viruses are not sensitive to antibiotics. The first antibiotics were extracted from fungal cultures: penicillium (penicillin), streptomyces (streptomycin). Today, they are produced by chemical synthesis. Antibiotics are divided into families: penicillins, cephalosporins, macrolides, tetracyclines (cyclins), sulfonamides, aminoglycosides, lincosanides, phenicoles, polymyxins, quinolones, imidazoles and others.
Inappropriate use of antibiotics can encourage the emergence of resistance: use antibiotics only when prescribed by a doctor, respect their dosage and duration, and do not give or advise another person to take an antibiotic you have been prescribed.
See article: Antibiotic families
Accumulation of air or gas in the intestine.
See article: Bloating, flatulence and aerophagia
The strict medical meaning of diarrhea is "the emission of stools that are too frequent and too abundant". In fact, common sense equates diarrhea with the notion of frequent, liquid stools. Normally, stools are pasty, but the emission of liquid or barely-formed stools, with no associated pain or particular disorder, is not pathological. Diarrhea occurs when liquid stools are passed repeatedly throughout the day, and the need for them is urgent or painful.
Many drugs can accelerate intestinal transit and make stools more liquid, without this undesirable effect being a real cause for concern.
Antibiotics can alter the digestive flora, essential for digestion, and cause diarrhoea, which is more or less uncomfortable but benign. The effect may appear immediately or after a few days' treatment. A serious and exceptional form of diarrhea, pseudomembranous colitis, may be observed after antibiotic treatment; this condition is characterized by the emission of mucus and false membranes (resembling flaps of skin) associated with abdominal pain; constipation may replace the initial diarrhea. Pseudomembranous colitis may occur several days after antibiotic treatment has stopped, and requires urgent medical advice.
See article: Diarrhea and gastroenteritis in adults or Diarrhea and gastroenteritis in children
Inability of the liver to fulfill its function, which is essentially the elimination of certain waste products, but also the synthesis of many biological substances essential to the body: albumin, cholesterol and coagulation factors (vitamin K, etc.).
Drug that protects the digestive tract by lining the mucosa with a protective film and reducing stomach acidity. This type of medication may interfere with the absorption of other drugs.
Inflammatory disease of the rectum and colon, which progresses in flare-ups. Each flare-up is accompanied by fever and bloody, phlegmy stools.
See article: Hemorrhagic rectocolitis.
Treatment that eliminates or reduces the symptoms of a disease without attacking its cause.
The passage of food from the stomach to elimination as stool.
Abbreviation for human immunodeficiency virus (HIV), responsible for an infection that can progress to AIDS.
A distinction is made between HIV-1 (responsible for the global epidemic) and HIV-2 (much less widespread than HIV-1, found mainly in West Africa).
See article: HIV/AIDS infection.
Bloating is the swelling of the stomach caused by the accumulation of gas in the intestine or stomach. This gas comes mainly from the fermentation of certain foods (starchy foods, pulses, etc.) but also from air swallowed when eating or chewing gum. It can also come from gas trapped in certain foods that is released in the stomach. This intestinal…
Read the article on the blogBloating is defined by a feeling of swelling in the abdomen (meteorism) and the need to belch or pass gas. There are several types: Bloating of the stomach leads to a feeling of heaviness in the stomach. It is also accompanied by an exaggerated intake of air (aerophagia). Bloating of the small intestine therefore occurs in the aftermath of surgery…
Read the article on the blogProbiotics are living microorganisms that have been shown to benefit the health of the host when given in adequate doses. Lactobacillus and Bifidobacterium species are most commonly used as probiotics. The yeast Saccharomyces boulardii as well as some species of E. coli and Bacillus are also used. Among the newcomers, we can also count Clostridium butyricum, recently authorized as a…
Read the article on the blog
