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Mildac 600 mg for Depressive Symptoms, 20 Tablets
Over-the-counter medication

Mildac 600 mg for Depressive Symptoms, 20 Tablets

Brand : Menarini Menarini

Mildac 600 mg for Depressive Symptoms is a herbal medicine made from St. John's wort, indicated for the short-term treatment of mild and transient depressive symptoms.

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For warnings, precautions, and contraindications, please refer to the package insert.

When should you use Mildac 600 mg for depressive symptoms to restore emotional balance?

Temporary sadness, a loss of motivation, or sleep disturbances can sometimes set in and weigh on daily life. When your mood remains low for several days, it becomes difficult to regain your usual energy. Mildac 600 mg for Depressive Symptoms is a traditional herbal medicine intended for adults, used for the short-term treatment of transient states of sadness accompanied by a loss of interest and sleep disturbances. It is traditionally used for mild and temporary depressive symptoms.

Its main active ingredient, St. John’s wort, acts a bit like a conductor helping musicians find the right rhythm. When certain substances involved in mood seem out of balance, this medicinal plant helps support emotional balance and restore greater mental stability. Gradually, daily life feels less burdensome and emotions become easier to manage.

During times when you feel drained, unmotivated, or constantly tired, regaining a little momentum can seem difficult. Some people describe this feeling as a battery that struggles to recharge despite rest. Thanks to the effects of St. John’s wort, Mildac 600 mg can help promote better mood balance and provide support during periods marked by low motivation or a temporary feeling of low spirits.

Sleep disturbances are often closely linked to mood. An overactive mind can make it difficult to fall asleep or result in nights of poor-quality sleep. By helping to soothe emotional fluctuations, St. John’s wort can contribute to a more positive cycle between sleep, energy, and mental stability.

This traditional herbal remedy is intended for adults experiencing mild and temporary depressive symptoms. If symptoms persist, intensify, or significantly impact personal and professional life, medical advice is essential to assess the situation and guide the patient toward appropriate care.

To support periods of nervous exhaustion or reduced stress resilience, Naturactive Rhodiola can be taken as a complementary supplement to create a synergistic effect: St. John’s wort works primarily on fragile mood, while rhodiola helps the body better adapt to the emotional stresses of daily life.

How should this medication be used?

Takeone tablet daily, swallowed with a large glass of water,preferably in the morning. Regular use helps gradually restore emotional balance and maximize the benefits of St. John’s wort.

The effects are not always immediate. Like a plant that takes time to take root before blooming, St. John’s wort works gradually. It may take several weeks of use before you notice an improvement in emotional well-being. Do not exceed 15 days of treatment without medical advice.

For adults only. Read the package insert carefully before use. If symptoms persist or worsen, ask your pharmacist for advice or consult your doctor. Store at a temperature not exceeding +25°C.

Share your feedback on the usage instructions and dosage of Mildac 600 mg for depressive symptoms with our partner Avis Vérifiés after your purchase.

Precautions

  • For adults only.
  • Not recommended during pregnancy or while breastfeeding without medical advice.
  • Do not use in combination with certain medications, including oral anticoagulants, oral contraceptives, immunosuppressants, tyrosine kinase inhibitors, digoxin, theophylline, irinotecan, carbamazepine, telithromycin, propafenone, anticonvulsants, or certain antiviral treatments.
  • Use caution with antidepressants, MAOIs, or medications that increase serotonin levels due to the risk of serotonin syndrome.
  • Avoid prolonged exposure to sunlight or UV rays due to a reported risk of skin photosensitivity associated with St. John’s wort.
  • Consult your pharmacist if you are currently undergoing treatment.

Possible side effects:

  • Digestive disturbances may occur in some people.
  • Photosensitivity-like skin reactions have been reported: avoid prolonged exposure to sunlight or UV rays during treatment.
  • A few rare cases of serotonin syndrome (nausea, dizziness, headache, anxiety, abdominal pain, agitation, or mental confusion) have been observed when used in combination with certain antidepressants, particularly in elderly patients.

If you are currently taking any other medications, always consult your pharmacist before starting Mildac 600 mg for depressive symptoms.

What is the composition of this medication for emotional well-being?

The active ingredient is:
St. John’s Wort (Hypericum perforatum L.) (quantified dry extract of flowering tops) ............. 624 mg
Per coated tablet
Standardized to:
0.1 to 0.3% total hypericins expressed as hypericin,
at least 6% flavonoids (corresponding to at least 1.5% rutin),
maximum 6% hyperforin
Extraction solvent: 80% V/V methanol
Drug-to-native extract ratio: 3–7:1

Other components are:
ascorbic acid, microcrystalline cellulose, croscarmellose sodium, iron oxide (E172), hypromellose, stearic acid, magnesium stearate, sodium saccharin, precipitated silica, titanium dioxide (E171), vanillin.

Packaging:

Box of 20 coated tablets. Available at the best price in our online pharmacy.

Our expert advice on Mildac 600 mg: Depressive Symptoms and Regaining Emotional Balance

When your mood is low, your daily routine often plays just as important a role as the treatment itself. Try to maintain a regular sleep schedule, get some natural light every day, and stay moderately active, even if only for a short time. A 20-minute walk can sometimes act as a “reset button” for the mind. If you’re already taking medication, always inform your pharmacist if you’re using St. John’s wort: this herb has numerous drug interactions that require special caution.

FAQ

Does Mildac 600 mg work immediately?
No. St. John’s wort works gradually. It may take several weeks before you notice an improvement in your emotional well-being.

Can Mildac 600 mg be taken with an antidepressant?
Special caution is required. Certain combinations may increase the risk of serotonin syndrome. Always consult your doctor or pharmacist.

Can Mildac 600 mg interact with other medications?
Yes. St. John’s wort is known to interact with many medications, including certain oral contraceptives, anticoagulants, and immunosuppressants. It is recommended to consult a pharmacist before taking it.

Pharmacovigilance Report an adverse drug reaction(s)

Download PDF leaflet

NOTICE

ANSM - Last updated: 12/10/2016

Name of the medicinal product

MILDAC 600 mg coated tablet

St. John's wort (dry extract)

framed

Please read this leaflet carefully before you start taking this medicine because it contains important information for you.

You should always take this medication exactly as prescribed in this leaflet or by your doctor or pharmacist.

· Keep this leaflet. You might need to read it again.

· Ask your pharmacist for advice or information.

· If you experience any of the side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. See section 4.

· You should contact your doctor if you experience no improvement or if you feel less well 15 days.

Do not use this medication for children.

What is in this leaflet?

1. What is Mildac 600 mg, coated tablet and in which cases it is used?

2. What should I know before taking Mildac 600 mg coated tablet?

3. How to take Mildac 600 mg, coated tablet?

4. What are the possible side effects?

5. How to store Mildac 600 mg coated tablet?

6. Package contents and other information.

1. WHAT IS MILDAC 600 mg coated tablet AND WHAT IT IS USED FOR?

Pharmacotherapeutic group - ATC code: Herbal medicinal product

Herbal medication traditionally used in the treatment of mild and transient depressive manifestations.

You should contact your doctor if you experience no improvement or feel less well after 15 days.

2. BEFORE YOU TAKE MILDAC 600 mg, coated tablet?

Do not take MILDAC 600 mg, coated tablet:

· if you are allergic (hypersensitive) to the active substance or to any of the other ingredients of this medication mentioned in section 6.

· In combination with anti-coagulants, anti-epileptics, contraceptives (estrogens and progestins), digoxin (used to treat heart disease), immunosuppressants (used for organ transplantation), protease inhibitors used in the treatment of HIV infection), cobicistat, daclatasvir, ledipasvir and dasabuvir (used in the treatment of hepatitis C), tyrosine kinase inhibitors (used in the treatment of certain cancers) (antimycotic), itraconazole and voriconazole (antifungal), lurasidone (used in schizophrenia), oxycodone (analgesic), rilpivirine (used in the treatment of certain cancers) theophylline and aminophylline (used in the treatment of asthma and certain respiratory diseases), ticagrelor (platelet anti-agregant), vismodegib (used in (see section "Other medicines and MILDAC 600 mg, coated tablet"), verapamil (used in the treatment of heart disease).

 

 

Warnings and Precautions

Talk to your doctor or pharmacist before taking MILDAC 600 mg coated tablet .

It is necessary that you take a medical opinion before starting treatment if you are being treated with other medicines (see section "Other medicines").

The antidepressant properties of MILDAC 600 mg coated tablets usually appear within the first 4 weeks after initiation of therapy. If symptoms persist, it is necessary to consult your doctor.

Use in children under 18 years is not recommended due to the lack of sufficient data.

Avoid prolonged exposure to the sun during treatment, due to the risk of skin reactions resembling sunburn (photosensitivity).

If you have to undergo surgery, tell your doctor if you are taking MILDAC 600 mg coated tablet.

Other medicines and MILDAC 600 mg, coated tablet

Inform your doctor or pharmacist if you are taking or have recently taken or may be taking any other medicines.

Inform your doctor or pharmacist if you are taking or have recently taken or may be taking any other medicines, MILDAC 600 mg, coated tablet may cause a decrease in the therapeutic effect of other medicines.

MILDAC 600 mg, coated tablet should not be taken with anticoagulants, antiepileptics, contraceptives (estrogen-progestin and progestin), digoxin (used to treat heart disease), immunosuppressants (used for organ transplants) protease inhibitors (used in the treatment of HIV infection), cobicistat, daclatasvir, ledipasvir and dasabuvir (used in the treatment of hepatitis C), tyrosine kinase inhibitors (used in the (antimycotic), itraconazole and voriconazole (antifungal), lurasidone (used in schizophrenia), oxycodone (analgesic), rilpivirine (used in the treatment of certain cancers) in the treatment of HIV infection), theophylline and aminophylline (used in the treatment of asthma and certain respiratory diseases), ticagrelor (anti-aggregating p vismodegib (used in the treatment of certain cancers), verapamil (used in the treatment of heart disease).

Inform your doctor or pharmacist if you are taking a drug containing any of the active ingredients:

· baedaquilin (used to treat tuberculosis)

· carbamazepine (used to treat epilepsy)

· cyproterone (used to treat certain hormonal diseases),

· dolutegravir (used to treat HIV)

· dronedarone and propafenone (used to treat heart rhythm disorders),

· eribulin (used in the treatment of certain cancers)

· idelalisib (used in the treatment of certain cancers)

· ivabradine (used to treat angina),

· lomitapide (used in some cases of familial hypercholesterolemia)

· macitentan (used in the treatment of pulmonary arterial hypertension)

· maraviroc (used in the treatment of HIV)

· quetiapine (used in the treatment of schizophrenia)

· siméprévir (used in the treatment of hepatitis C)

· simvastatin (used in the treatment of hypercholesterolemia or dyslipidemia)

· sofosbuvir (used in the treatment of hepatitis C)

· telithromycin and linezolid (antibiotics)

· ulipristal (emergency contraceptive).

If your doctor prescribes other medicines for depression, tell your doctor that you are already taking MILDAC 600 mg coated tablets.

 

MILDAC 600 mg, tablet coated with food, drinks and alcohol

Not applicable.

Pregnancy and breast feeding

If you are pregnant or breastfeeding, think you may be pregnant or plan a pregnancy, ask your doctor for advice or to your pharmacist before taking any medication.

Sport

Not applicable.

Driving and using machines

Not applicable.

MILDAC 600 mg, coated tablet contains

Not applicable.

3. HOW TO TAKE MILDAC 600 mg coated tablet?

Always take this medication exactly as prescribed by your doctor or pharmacist. Check with your doctor or pharmacist if you are not sure.

Reserved for adults (from 18 years) and the elderly.

Always take this medication exactly as prescribed in this leaflet or as directed by your doctor or pharmacist. Check with your doctor or pharmacist if you are not sure.

The recommended dose is 1 tablet per day, preferably in the morning.

If you take more than Mildac 600 mg, coated tablet you should:

Immediately consult your doctor or pharmacist.

If you forget to take Mildac 600 mg, coated tablet:

Do not take a double dose to make up for the missed dose .

If you stop taking Mildac 600 mg, coated tablet:

Not applicable.

If you have any further questions on the use of this medication, ask your doctor or pharmacist.

4. WHAT ARE POSSIBLE SIDE EFFECTS?

Like all medicines, this medicine may cause side effects, although not everybody gets them.

Like all medicines, Mildac 600 mg, coated tablet is likely to have side effects, although not everyone is subject to it.

Digestive disorders, fatigue, agitation or rash may occur. Possibility of excessive sensitivity to sunlight (photosensitivity) with skin reactions resembling sunburn in case of sun exposure during treatment.

Declaration of side effects

If you experience any side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Centers of Pharmacovigilance 

By reporting adverse reactions, you are helping to provide more information about the safety of the drug.

5. HOW TO STORE MILDAC 600 mg coated tablet?

Keep this medicine out of the reach and sight of children.

Do not use this medicine after the expiry date which is stated on the package. The expiry date refers to the last day of that month.

Do not use this medication if you notice any signs of deterioration.

Do not throw any medicines into drains or rubbish. Ask your pharmacist to remove any medications you are no longer using. These measures will help protect the environment.

6. PACKAGE CONTENTS AND OTHER INFORMATION

What MILDAC 600 mg contains: coated tablet

· The active substance is:

St. John's wort ( Hypericum perforatum L.) (methanolic dry extract (80% V / V)) 612 mg

· The excipients are: ascorbic acid, microcrystalline cellulose, croscarmellose sodium, iron oxide (E172), hypromellose, stearic acid, magnesium stearate, sodium saccharin, precipitated silica, titanium dioxide (E 171), vanillin.

What Mildac 600 mg coated tablet looks like and contents of the pack

Coated tablet.

Box of 15 and 20 tablets.

Not all pack sizes may be marketed.

Marketing Authorization Holder

DR. WILLMAR SCHWABE GmbH & Co

WILLMAR-SCHWABE Str. 4

76227 KARLSRUHE

GERMANY

Marketing Authorization Operator

MERCK MEDICATION FAMILIALE

18C BOULEVARD WINSTON CHURCHILL

21000 DIJON

LA FRANCE

Maker

DR. WILLMAR SCHWABE GmbH & Co

WILLMAR-SCHWABE Str. 4

76227 KARLSRUHE

GERMANY

Names of the medicinal product in the Member States of the European Economic Area

Not applicable.

The last date on which this leaflet was revised is:

[to be completed later by the holder]

Other

Detailed information on this medicine is available on the ANSM website (France).

VIDAL OF THE FAMILY

MILDAC

Phytotherapy

St. John's wort

. Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS (summary)

MILDAC 300 mg: tablet; box of 40.
-

MILDAC 600 mg: tablet; box of 15.
-

Merck Family Medication Laboratory

COMPOSITION (summary)
p cp p cp
St. John's wort, extract 300 mg 600 mg
Lactose +

INDICATIONS (summary)
This medicine contains an extract of St. John's wort, a plant that has been the subject of scientific research in the treatment of depressive states . Data from these studies indicate that St. John's Wort has activity in the treatment of mild depression. Since these studies have focused on time-limited intake, this drug can not currently be considered a true antidepressant and is recommended only in the treatment of transient depressive states.
It is traditionally used in the treatment of mild and transient depressive manifestations.
CONTRAINDICATIONS (summary)
This medication should not be combined with oral anticoagulants , protease inhibitors, or ciclosporin-containing medicines.
WARNING (Contents)
Depression is a serious illness that warrants medical advice when the state of sadness is not justified by a major event or when it lasts long after a possible triggering event.
Although this drug is over-the-counter and contains only plant extract, it may cause drug interactions, particularly with oral contraceptives (pills). Its effectiveness should not be overestimated and the use of a "classic" antidepressant , prescribed by a physician, combined with psychological support, may be necessary.
DRUG INTERACTIONS (summary)
This medication should not be combined with oral anticoagulants , antiproteases , certain anticonvulsants or ciclosporin: decreased efficacy with St. John's wort, or increased blood levels and risk of overdose if drug is discontinued .
It may interact with oral contraceptives , antidepressants inhibiting serotonin reuptake , triptan antimigraine drugs, and drugs containing digoxin, theophylline, and phenytoin.
PREGNANCY AND BREAST-FEEDING (summary)
The effect of this medication during pregnancy or lactation is not well known: only your doctor can evaluate the possible risk of its use in your case.
DIRECTIONS FOR USE AND DOSAGE (summary)
The tablets should be swallowed with a glass of water, preferably at regular time.

Usual dosage:

  • Adult: 1 tablet 300 mg, 1 to 3 times daily or 1 tablet 600 mg daily, preferably in the morning.
TIPS (summary)
The treatment of a depressive state , even if light, is not just about taking medication. The support of a professional is often a valuable aid to take a difficult course or reflect on the conscious or unconscious causes that are at the origin of this state.
POSSIBLE ADVERSE EFFECTS (summary)
Digestive disorders , photosensitization .


GLOSSARY (summary)


anti coagulants
Medication that prevents blood from coagulating and therefore prevents clots from forming in the blood vessels.
Anticoagulants are used to treat or prevent phlebitis, pulmonary embolism, certain infarcts. They also prevent the formation of clots in the heart during rhythm disorders such as atrial fibrillation or in the case of an artificial heart valve.
There are two main types of anticoagulants:
  • oral anticoagulants, which block the action of vitamin K (antivitamin K, or AVK) and whose effectiveness is controlled by a blood test: INR (formerly TP);
  • injectable anticoagulants derived from heparin, the efficacy of which can be controlled by the blood assay of anti-Xa activity, Howell's Time (TH) or Cephalin Kaolin Time (TCK) depending on the products used. A regular dosage of blood platelets is necessary throughout the life of a heparin derivative.


anticonvulsants
Medication used to treat convulsions and various forms of epilepsy. Anticonvulsants are classified as barbiturates (phenobarbital) and non-barbiturates, which are currently the most widely used.


antidepressant
Medication that works against depression. Some antidepressants are also used to combat obsessive-compulsive disorder, generalized anxiety, certain rebellious pain, enuresis, etc.
Depending on their mode of action and adverse effects, antidepressants are divided into different families: imipraminic antidepressants, serotonin reuptake inhibitors, selective or non-selective MAOIs. Finally, other antidepressants do not belong to any of these families, because they possess original properties.
The mode of action of antidepressants has two main aspects: the relief of moral suffering and the fight against inhibition which removes all will to action from the depressed. There may be a time lag between these two effects: moral suffering may persist, while the capacity for action reappears. During this short period, the risk of suicide in some depressed people can be increased. The physician takes it into account in its prescription (possible association with a tranquillizer) and it must imperatively be respected.


protease inhibitors
An antiretroviral drug which acts by blocking an enzyme (protease) necessary for the maturation of the AIDS virus (HIV) in infected cells. This type of drug blocks one of the stages of reproduction of the virus, but does not allow its eradication. It is most often used in combination with other antiretrovirals.


contraceptives
Who opposes conception: oral contraceptive (pill), local (IUD, spermicide, diaphragm and condom).


depressive states
State of moral suffering associating a demotivation, a fatigue, a feeling of uselessness, of self-depreciation. In the absence of treatment, the depressive state may develop into a serious depression with a feeling of incurability, guilt, and a suicidal risk.


inhibitors of serotonin reuptake
Antidepressant increases the amount of serotonin in the brain, limiting its recapture. Some IRSs are also used for the treatment of obsessive compulsive disorder (OCD) and anxiety.
See also: serotonergic antidepressant.


photosensitivity
Abnormal sensitivity of the skin to light or ultraviolet rays due to a drug or a natural or chemical substance.


overdose
Taking an excessive amount of a drug exposes you to an increase in the intensity of adverse effects, or even to the appearance of particular adverse effects.
This overdose may result from accidental or voluntary poisoning for suicide, so consult your local Poison Control Center (listed in the appendix to the book). However, in most cases, overdose is the result of an error in the understanding of the prescription, or the search for an increase in efficacy by exceeding the recommended dosage. Finally, untimely self-medication may lead to excessive absorption of the same substance contained in different drugs. Some drugs are particularly prone to this risk because they are (wrongly) considered to be harmless: vitamins A and D, aspirin, etc. Stopping or decreasing drug intake helps to remove the disorders associated with an overdose.


triptans
Name of a chemical family of vasoconstrictors used in the treatment of migraine. Compared to vasoconstrictors derived from rye ergot, triptans have the advantage of acting more specifically on the arteries of the brain.


Digestive disorders
Set of symptoms indicating irritation or malfunction of the digestive tract. One or more disorders may be present: nausea, vomiting, aerophagia, abdominal pain, heartburn, bloating, flatulence, diarrhea or constipation, etc. Antibiotics can promote candidiasis, often responsible for digestive disorders.

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