Mildac 600mg Manifestations of depression 20 Tablets

Mildac 600mg St John's Wort: Relieve your depressive symptoms naturally

Minor depression

This is a chronic disorder (lasting at least two years) defined as follows:

• depressed mood most of the day, more than every other day for two years ;
• during depressive phases, at least two of the following symptoms are present :

• loss of appetite or, on the contrary, hyperphagia,
• insomnia or hypersomnia,
• low energy or fatigue,
• low self-esteem,
• difficulty concentrating or making decisions,
• feelings of loss of hope.

• the patient is never without these symptoms for more than 2 consecutive months;
• these symptoms cause suffering and inconvenience in socio-professional life.

Mildac 600mg St John's Wort: Regain your emotional balance

Mediflor Mildac 600mg by Mediflor Laboratories is a herbal medicine in coated tablet form used for the short-term treatment of temporary sadness, accompanied by loss of interest and sleep disorders.

For adults only, Mediflor Mildac 600mg Tablets is traditionally used for mild, transient depression.

Relieve your depressive symptoms and regain your zest for life

Fight the symptoms of depression with Mildac

Say goodbye to depression and regain your vitality with Mildac 600mg St John's Wort. If you suffer from depressive symptoms such as persistent sadness, constant fatigue and loss of interest in the activities you love, this natural dietary supplement is for you. Mildac contains a standardized extract of St John's Wort, a plant with antidepressant properties that have been recognized for centuries.

Thanks to its concentrated formula, each tablet of Mildac 600mg provides you with the optimal dose of St. John's Wort to relieve your symptoms of depression. St John's Wort works by balancing neurotransmitters in the brain, helping to improve your mood and reduce anxiety. By taking Mildac regularly, you'll experience a reduction in sadness and apathy, as well as an increase in energy and optimism.

A natural solution with no undesirable side effects

One of the major advantages of Mildac 600mg St John's Wort is its all-natural nature. Unlike prescription drugs, Mildac is a dietary supplement based on plant extracts, which means it doesn't have the common side effects associated with synthetic antidepressants.

Thanks to the medicinal plant St. John's Wort, Mildac is a safe, natural alternative for mild to moderate depression. You can feel relieved knowing you don't have to worry about unwanted side effects such as drowsiness, weight gain or dependence. Opt for a safe, natural approach with Mildac to regain your emotional well-being.

How to use Mildac for optimal results?

Recommended dosage

To get the best results from Mildac 600mg St John's Wort, it's essential to follow the recommended dosage instructions. We recommend taking one tablet a day with a glass of water, preferably in the morning. Taking Mildac regularly is important for maintaining a stable emotional balance and reduced depressive symptoms.

Bear in mind that it may take some time for the full effects of Mildac to become apparent. It is therefore recommended to continue using the product for at least 4 to 6 weeks before evaluating the results. Be patient and consistent in your approach to obtaining the full benefits of Mildac. Do not exceed 15 days' treatment without medical advice.

For adults only. If symptoms persist, consult your doctor. Store at a temperature not exceeding +25°C.

Incorporate Mildac into your daily routine

To optimize the effects of Mildac, we recommend incorporating it into your daily well-being routine. Here are a few tips to maximize the benefits of Mildac:

• Establish a regular routine: Take your Mildac tablet at the same time every day, preferably in the morning. This will enable you to maintain a constant concentration of active ingredients in your body.
• Adopt a healthy lifestyle: Complement the action of Mildac by adopting healthy lifestyle habits. Exercise regularly, eat a balanced diet and allow yourself time for relaxation.
• Pay attention to your emotional well-being: Take the time to connect with your emotions and express yourself. Meditation, journaling or sharing with loved ones can be beneficial practices to foster your emotional balance.

Find your happiness with Mildac 600mg St John's Wort

A holistic approach to mental well-being

Mildac 600mg St John's Wort offers a holistic approach to your mental well-being. By relieving depressive symptoms, this dietary supplement enables you to rediscover your zest for life and take full part in all of life's wonders. Don't let depression rob you of your happiness. Choose Mildac and rediscover your inner radiance.

Sustained results for a better quality of life

By using Mildac regularly and continuously, you can expect lasting results. This dietary supplement works gently to restore your emotional balance, enabling you to enjoy a better quality of life. You'll feel more in tune with yourself, ready to take on daily challenges with confidence and serenity.

Take the first step towards a fulfilling life

Don't let depression dictate your life. Take the first step towards a fulfilling life by choosing Mildac 600mg St John's Wort. With its natural formula, long-lasting benefits and ability to relieve depressive symptoms, Mildac is your ally in regaining vitality and happiness. Give yourself the gift of emotional well-being with Mildac.

Mildac 600mg composition

Methanolic dry extract of St John's wort 612 mg. Excipients : Ascorbic acid, Microcrystalline cellulose, Croscarmellose sodium, Iron oxide (E 172), Hypromellose, Stearic acid, Magnesium stearate, Saccharin sodium, Colloidal silica, Titanium dioxide (E 171), Talc, Vanillin, qsp 1 film-coated tablet.

Precautions for use with mildac 600mg

This medicine is contraindicated in the following situations:

In association with :

• oral anticoagulants
• Anticonvulsants (ethosuximide, felbamate, fosphenytoin, lamotrigine, phenobarbital, phenytoin, primidone, tiagabine, topiramate, valproic acid, valpromide) except carbamazepine (see not recommended in combination), gabapentin and vigabatrin,
• Oral contraceptives,
• digoxin
• Immunosuppressants (ciclosporin, sirolimus, tacrolimus)
• Protease inhibitors (amprenavir, atazanavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir),
• Tyrosine kinase inhibitors
• Irinotecan,
• theophylline.

Interactions with other drugs and other forms of interaction :

Contraindicated associations:

• Oral anticoagulants: Decrease in plasma concentrations of oral anticoagulants, with the risk of reduced efficacy or even cancellation of the effect, with potentially serious consequences (thrombotic event). In the event of fortuitous association, do not stop taking St John's Wort abruptly, but check the INR before and then after stopping St John's Wort.
• Anticonvulsants (ethosuximide, felbamate, fosphenytoin, lamotrigine, phenobarbital, phenytoin, primidone, tiagabine, topiramate, valproic acid, valpromide) except carbamazepine (see not recommended in combination), gabapentin and vigabatrin: risk of reduced plasma concentrations and efficacy of anticonvulsant.
• Oral contraceptives (estroprogestins, progestins): Decrease in plasma concentrations of oral contraceptives, with risk of reduced efficacy or even reversal of effect. In case of accidental association, do not suddenly stop taking St. John's Wort.
• Digoxin: Decrease in digoxinemia, with risk of reduced efficacy or even loss of effect, with potentially serious consequences (decompensation of heart failure). In the event of accidental association, do not stop taking St. John's Wort abruptly, but check digoxin levels before and after stopping St. John's Wort.
• Immunosuppressants (ciclosporin, sirolimus, tacrolimus): Decreased blood levels and efficacy of immunosuppressants (or even nullification of effect), with risk of graft rejection. In the event of accidental association, do not abruptly stop taking St. John's Wort, but monitor blood levels of the immunosuppressant before and after stopping St. John's Wort.
• Protease inhibitors (amprenavir, atazanavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir): Decrease in protease inhibitor plasma concentrations, with the risk of reduced efficacy or even cancellation of the effect, with potentially serious consequences. In the event of fortuitous association, do not stop taking St. John's Wort abruptly, but check the efficacy of the protease inhibitor before and then after stopping St. John's Wort.
• Tyrosine kinase inhibitors: Decreased plasma concentrations and efficacy of tyrosine kinase inhibitors due to increased metabolism by St. John's Wort.
• Irinotecan: Decreased plasma concentrations of the active metabolite of irinotecan, with risk of cytotoxic treatment failure.
• Theophylline: Decrease in theophyllinemia, with risk of reduced efficacy or even nullification of the effect, with potentially serious consequences (onset of obstructive ventilatory disorder). In the event of accidental association, do not stop taking St. John's Wort abruptly, but check theophyllin levels before and after stopping St. John's Wort.

Unadvisable associations:

• Cabamazepine: Risk of decreased plasma concentrations and efficacy of anticonvulsant.
• Telithromycin: Decreased plasma concentrations of telithromycin, with risk of anti-infective treatment failure, due to increased hepatic metabolism of telithromycin by St. John's Wort.

Pharmacodynamic interactions:

Precautionary associations:

• Serotonin reuptake inhibitor antidepressants (citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline): Risk of serotonin syndrome: diarrhea, tachycardia, sweating, tremors, confusion, even coma. Regular clinical monitoring.
• Non-selective MAOIs (iproniazid): risk of serotonin syndrome: diarrhea, tachycardia, sweating, tremors, confusion, even coma; regular clinical monitoring.
• Selective A MAOIs (moclobemide, toloxatone): Risk of serotonin syndrome: diarrhea, tachycardia, sweating, tremors, confusion, even coma. Regular clinical monitoring.
• Linezolid: Risk of serotonin syndrome: diarrhea, tachycardia, sweating, tremors, confusion, even coma. Regular clinical monitoring.
• Propafenone: Decrease in propafenone plasma concentrations due to increased hepatic metabolism by St. John's wort.

Adverse effects:

• A few cases of serotonin syndrome (nausea, dizziness, headache, anxiety, abdominal pain, agitation, mental confusion) have been reported in the literature in elderly patients treated concomitantly with a serotonin reuptake inhibitor antidepressant and St. John's Wort. The syndromes regressed after St. John's wort was discontinued (see Interactions with other drugs and other forms of interaction).
• Digestive disorders and photosensitization-type skin reactions have been reported.

Overdosage :

No cases of overdosage have been reported.

Packaging

Box of 20 tablets.

Our expert opinion

What causes mood disorders?

The mechanisms behind the onset of MDLT remain poorly understood: many factors seem to come into play. We do know, however, that certain life events or contexts can be conducive to it: professional difficulties ("burn out"), family problems (bereavement, break-up...), menopause, smoking cessation...

Individual susceptibility certainly plays a decisive role. From a physical point of view, mood disorders are accompanied by disturbances in exchanges between neurotransmitters, the chemical "messengers" of the brain's neurons (serotonin, noradrenalin...).

Pharmacovigilance Report an adverse drug reaction(s)

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Phytotherapy

St. John's wort

. Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS ^(summary)

MILDAC 300 mg: tablet; box of 40.
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MILDAC 600 mg: tablet; box of 15.
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Merck Family Medication Laboratory

COMPOSITION ^(summary)

	p cp	p cp
St. John's wort, extract	300 mg	600 mg
Lactose	+

INDICATIONS ^(summary)

This medicine contains an extract of St. John's wort, a plant that has been the subject of scientific research in the treatment of depressive states . Data from these studies indicate that St. John's Wort has activity in the treatment of mild depression. Since these studies have focused on time-limited intake, this drug can not currently be considered a true antidepressant and is recommended only in the treatment of transient depressive states.
It is traditionally used in the treatment of mild and transient depressive manifestations.

CONTRAINDICATIONS ^(summary)

This medication should not be combined with oral anticoagulants , protease inhibitors, or ciclosporin-containing medicines.

WARNING ^(Contents)

Depression is a serious illness that warrants medical advice when the state of sadness is not justified by a major event or when it lasts long after a possible triggering event.
Although this drug is over-the-counter and contains only plant extract, it may cause drug interactions, particularly with oral contraceptives (pills). Its effectiveness should not be overestimated and the use of a "classic" antidepressant , prescribed by a physician, combined with psychological support, may be necessary.

DRUG INTERACTIONS ^(summary)

This medication should not be combined with oral anticoagulants , antiproteases , certain anticonvulsants or ciclosporin: decreased efficacy with St. John's wort, or increased blood levels and risk of overdose if drug is discontinued .
It may interact with oral contraceptives , antidepressants inhibiting serotonin reuptake , triptan antimigraine drugs, and drugs containing digoxin, theophylline, and phenytoin.

PREGNANCY AND BREAST-FEEDING ^(summary)

The effect of this medication during pregnancy or lactation is not well known: only your doctor can evaluate the possible risk of its use in your case.

DIRECTIONS FOR USE AND DOSAGE ^(summary)

The tablets should be swallowed with a glass of water, preferably at regular time.

Usual dosage:

• Adult: 1 tablet 300 mg, 1 to 3 times daily or 1 tablet 600 mg daily, preferably in the morning.
  

TIPS ^(summary)

The treatment of a depressive state , even if light, is not just about taking medication. The support of a professional is often a valuable aid to take a difficult course or reflect on the conscious or unconscious causes that are at the origin of this state.

POSSIBLE ADVERSE EFFECTS ^(summary)

Digestive disorders , photosensitization .

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GLOSSARY ^(summary)

anti coagulants
Medication that prevents blood from coagulating and therefore prevents clots from forming in the blood vessels.
Anticoagulants are used to treat or prevent phlebitis, pulmonary embolism, certain infarcts. They also prevent the formation of clots in the heart during rhythm disorders such as atrial fibrillation or in the case of an artificial heart valve.
There are two main types of anticoagulants:

• oral anticoagulants, which block the action of vitamin K (antivitamin K, or AVK) and whose effectiveness is controlled by a blood test: INR (formerly TP);
  

• injectable anticoagulants derived from heparin, the efficacy of which can be controlled by the blood assay of anti-Xa activity, Howell's Time (TH) or Cephalin Kaolin Time (TCK) depending on the products used. A regular dosage of blood platelets is necessary throughout the life of a heparin derivative.
  

anticonvulsants
Medication used to treat convulsions and various forms of epilepsy. Anticonvulsants are classified as barbiturates (phenobarbital) and non-barbiturates, which are currently the most widely used.


antidepressant
Medication that works against depression. Some antidepressants are also used to combat obsessive-compulsive disorder, generalized anxiety, certain rebellious pain, enuresis, etc.
Depending on their mode of action and adverse effects, antidepressants are divided into different families: imipraminic antidepressants, serotonin reuptake inhibitors, selective or non-selective MAOIs. Finally, other antidepressants do not belong to any of these families, because they possess original properties.
The mode of action of antidepressants has two main aspects: the relief of moral suffering and the fight against inhibition which removes all will to action from the depressed. There may be a time lag between these two effects: moral suffering may persist, while the capacity for action reappears. During this short period, the risk of suicide in some depressed people can be increased. The physician takes it into account in its prescription (possible association with a tranquillizer) and it must imperatively be respected.


protease inhibitors
An antiretroviral drug which acts by blocking an enzyme (protease) necessary for the maturation of the AIDS virus (HIV) in infected cells. This type of drug blocks one of the stages of reproduction of the virus, but does not allow its eradication. It is most often used in combination with other antiretrovirals.


contraceptives
Who opposes conception: oral contraceptive (pill), local (IUD, spermicide, diaphragm and condom).


depressive states
State of moral suffering associating a demotivation, a fatigue, a feeling of uselessness, of self-depreciation. In the absence of treatment, the depressive state may develop into a serious depression with a feeling of incurability, guilt, and a suicidal risk.


inhibitors of serotonin reuptake
Antidepressant increases the amount of serotonin in the brain, limiting its recapture. Some IRSs are also used for the treatment of obsessive compulsive disorder (OCD) and anxiety.
See also: serotonergic antidepressant.


photosensitivity
Abnormal sensitivity of the skin to light or ultraviolet rays due to a drug or a natural or chemical substance.


overdose
Taking an excessive amount of a drug exposes you to an increase in the intensity of adverse effects, or even to the appearance of particular adverse effects.
This overdose may result from accidental or voluntary poisoning for suicide, so consult your local Poison Control Center (listed in the appendix to the book). However, in most cases, overdose is the result of an error in the understanding of the prescription, or the search for an increase in efficacy by exceeding the recommended dosage. Finally, untimely self-medication may lead to excessive absorption of the same substance contained in different drugs. Some drugs are particularly prone to this risk because they are (wrongly) considered to be harmless: vitamins A and D, aspirin, etc. Stopping or decreasing drug intake helps to remove the disorders associated with an overdose.


triptans
Name of a chemical family of vasoconstrictors used in the treatment of migraine. Compared to vasoconstrictors derived from rye ergot, triptans have the advantage of acting more specifically on the arteries of the brain.


Digestive disorders
Set of symptoms indicating irritation or malfunction of the digestive tract. One or more disorders may be present: nausea, vomiting, aerophagia, abdominal pain, heartburn, bloating, flatulence, diarrhea or constipation, etc. Antibiotics can promote candidiasis, often responsible for digestive disorders.