Permixon 160 mg Serenoa repens capsules

Permixon 160 mg, 60 capsules, for the treatment of certain urinary disorders associated with benign prostatic hyperplasia

For warnings, precautions, and contraindications, please refer to the package insert for PERMIXON 160 mg.

If this medication is out of stock, we offer an equivalent dietary supplement, Prostamol, which contains the same active ingredient:saw palmetto (Serenoa repens).

Benign prostatic hyperplasia (BPH)—also known as prostate adenoma or benign prostatic hyperplasia—typically affects men over the age of 50.

Benign prostatic hyperplasia is characterized by an enlargement of the prostate. An enlarged prostate compresses the urethra and puts pressure on the bladder, leading to a frequent urge to urinate and various urinary problems, depending on the case (weaker and intermittent urine flow, pain, etc.).
Men with an enlarged prostate experience recurring difficulty when urinating. At first, they have trouble starting to urinate; then, because the urine stream is weak and intermittent, they feel as though they have never fully emptied their bladder. In addition, the urge to urinate occurs several times a night. Sometimes patients experience pain in the back and upper thighs.

Description of Permixon 160 mg Urinary Disorders

Permixon 160 mgis amedication made from a plant extractthat has decongestant properties on the urinary tract. Permixon 160 mg is recommended for thetreatment of certain urinary disorders(difficulty passing urine) associated with an enlarged prostate.

This plant-based medication contains 160 mg of a lipidosterolic extract from Serenoa repens, better known as the Florida palm. These active ingredients have a decongestant effect on urination. In the prostate, they reduce the action of the male hormone, a factor that promotes the development of prostate adenomas.

Experimental studies, conducted in animals or in vitro on prostate cells, have shown that the lipidosteroidal extract of Serenoa repens:

• exhibits non-competitive inhibitory properties against 5α-reductase (types 1 and 2), the enzyme that converts testosterone into its active metabolite, dihydrotestosterone;
• inhibits the formation of prostaglandins and leukotrienes (as demonstrated in polymorphonuclear cells);
• inhibits the proliferation of cells derived from benign prostatic hyperplasia and stimulated by growth factors.

Therapeutic class: Urology and Nephrology. Treatment of moderate urinary symptoms associated with benign prostatic hyperplasia in adult men. (G: Genitourinary system and sex hormones)

Indications for the prostate medication Permixon 160 mg

PERMIXON 160 mg is indicated for the treatment of moderate urinary symptoms associated with benign prostatic hyperplasia in adult men.

Directions for Use and Dosage of Permixon 160 mg

Adults:

• 2 capsules daily with meals.
• Take the capsules with a glass of water.
• The maximum duration of treatment is limited to 6 months.

Composition of Permixon 160 mg

Florida saw palmetto (Serenoa repens (W. Bartram) Small.) (fruit extract) 160 mg

Extraction solvent: hexane.

Excipients: Macrogol10,000.Capsule shell:gelatin, yellow iron oxide, indigotine, titanium dioxide.

Extraction solvent: hexane.

What are the medical treatment options for prostate problems?

In cases of acute prostatitis, antibiotic treatment is necessary. Caution is advised, as prostatitis can, in some cases, become chronic, leading to recurring infections, pain, or discomfort at varying intervals.

For symptomatic benign prostatic hyperplasia, treatment aims to improve quality of life and reduce symptoms by improving urinary flow. Many medications are available: alpha-blockers, 5-alpha-reductase inhibitors, herbal remedies (Cyprés walnut tea, Arkogélules pumpkin seed oil, Pygeum Africanum - Tadenan), dietary supplements (Solgar Prostate Support, Prostaform for prostate-related urinary disorders,Androbiane Pileje for urinary comfort), homeopathic medicines (L6 Juniperus Complex Lehning) and gemmotherapy products (Prestagem Herbalgem)
Surgical treatment may also be recommended if medical treatment fails (10 to 20% of cases) or as an initial option in cases of severe discomfort or complications.

What are the consequences of prostate problems?

When they cause symptoms, these can be particularly bothersome: very frequent urges to urinate, difficulty urinating or emptying the bladder, pain, etc. It is therefore important to seek medical attention without delay.

Precautions

Contraindications

Never take PERMIXON 160 mg capsules in the following case:
· If you are allergic to the active ingredient (Florida saw palmetto extract) or to any of the other ingredients listed in Section 6.

Precautions

Take special care with PERMIXON 160 mg capsules:

• Taking this medication on an empty stomach may sometimes cause nausea.
• During your treatment, your doctor will continue to monitor your prostate regularly. Under no circumstances can PERMIXON 160 mg capsules replace surgery when it is necessary.

Packaging

Permixon 160 mg is available in boxes of 60 and 180 capsules (40 11).

Medication Warnings

Please note: PERMIXON 160 mg is not like other medications. Read the medication guide carefully before ordering. Keep medications out of the reach of children. If symptoms persist, consult your doctor or pharmacist. Be aware of potential interactions with your current medications.

• Please inform your online pharmacist of any current treatments to identify potential interactions. The order confirmation form includes a custom message field for this purpose.
• Click here to view the package insert for this medication on the website of the National Agency for Medicines and Health Products Safety.

Advice from your expert pharmacist

Benignprostatichyperplasia (BPH) is a non-cancerous (benign)enlargementof theprostatethat can make urination difficult. Theprostateincreases in size with age. Men may experience difficulty urinating and have a more frequent and urgent need to urinate. 

Benign prostatic hyperplasia (BPH)—also known as prostate adenoma or benign prostatic hyperplasia—typically affects men over the age of 50. It is characterized byan enlargement of the prostate, caused by an adenoma(benign tumor) that most often develops in the partof theprostate that is in contact with the urethra, known as the transition zone. A prostate adenoma is not cancer.It is a benign condition thatposes no major risk to the individual but can cause urinary problems due to the pressure it exerts on the urethra.

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Plant extract

Serenoa repens

. Presentations . Composition . Indications . Warning . Directions for use and dosage . Undesirable effects . Lexicon

PRESENTATIONS ^(summary)

PERMIXON: capsule (green); box of 60.
Refunded at 30%. - price: 22,42 euro (s).

PERMIXON: capsule (green); box of 180.
Refunded at 30%. - price: 63,37 euro (s).

Laboratory Pierre Fabre Medicine

COMPOSITION ^(summary)

	p gel
Serenoa repens, lipidosteric extract	160 mg

INDICATIONS ^(summary)

This medicine contains a plant extract that has decongestant properties on the urinary tract. It slows down the action of the male hormone on the prostate, making it possible to delay the development of prostate adenomas.
It is used in the treatment of urinary disorders related to an adenoma of the prostate .

WARNING ^(Contents)

If the condition persists, talk to your doctor.
This medicine can not cure an adenoma of the prostate ; If your urine is blocked progressively or suddenly, consult your doctor.

DIRECTIONS FOR USE AND DOSAGE ^(summary)

This medication should be taken during meals to avoid possible nausea.

Usual dosage:

1 capsule morning and evening.

POSSIBLE ADVERSE EFFECTS ^(summary)

Nausea, abdominal pain.
Rarely: rash .
Exceptionally: increased breast volume.

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GLOSSARY ^(summary)

adenoma of the prostate
Increase in the volume of the prostate gland located under the bladder of the man. This increase in volume is benign, has no relationship to cancer, but can interfere with the passage of urine into the urethra through the gland.
Symptoms that suggest the presence of a prostate adenoma are:

• difficulty urinating (slowness, weakness of the spray);
  
• the need to get up several times at night to urinate;
  
• urges to urinate imperiously and difficult to control.
  

Certain drugs, especially atropinic drugs, may have the undesirable effect of aggravating the discomfort and may lead to a total blockage of the evacuation of the bladder. They are therefore contraindicated or should be used cautiously in men with the symptoms described above.


skin rash
Appearance of pimples or plaques on the skin. These lesions can be due to a food, a drug, and translate an allergy or a toxic effect. Many viruses can also cause pimple eruptions: rubella, roseola and measles are the most common.


hormone
A substance produced by the body and transported by the blood, intended to regulate the activity of certain glands or organs.