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ACTIVIR 5% HERPES CREAM TUBE 2G
Over-the-counter medication

ACTIVIR 5% HERPES CREAM TUBE 2G

Brand : GlaxoSmithKline GlaxoSmithKline
€3.57 EXCL. VAT €3.93 INCL. VAT
This product is an over-the-counter medication. Please consult the package insert before ordering online.
In stock
Reference : 3400934573491
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ACTIVIR 5% CREAM TUBE 2G: Activir 5% is indicated for the treatment of acute localized herpes labialis (also called "cold sores"), in adults and children over 6 years.

ACTIVATE 5% 2G TUBE CREAM

Herpes labialis or cold sores is a rash in the form of a "bunch" of vesicles on the lips due to a virus. It is due to herpes simplex virus 1 (HSV1), present in the body since a primary infection. Frequent pathology, it returns during episodes of infection, exposure to the sun ...

Description of ACTIVIR 5% TUBE CREAM 2G

Activir 5% is indicated for the treatment of localized cold sores outbreaks (also called "cold sores") , in adults and children over 6 years of age.

Cold sores cannot be cured permanently, but there are treatments to speed healing. Symptoms resolve spontaneously in seven to ten days.
The treatment of cold sores (or cold sores) is based on:

  • the application of creams that accelerate healing with an average gain of approximately 2 days;
  • the application of specific patches for cold sores , which in addition to speeding up healing, limit contamination.

Using advice and opinion on ACTIVIR 5% 2G TUBE CREAM

Administration mode
Dermal.

  • Start applications at the first itching or burning before the vesicles appear, the treatment being more effective if it is started at the first symptoms announcing a cold sore or cold sore outbreak.
  • Wash your hands thoroughly before and after each application of the cream on your cold sore to avoid spreading the infection.
  • Apply the cream with your finger, extending widely around the lesion.
  • Close the dispensing tube or pump properly after use.
  • How to use the pump:
  • It is recommended to carry out at least 3 to 4 slow and complete pressures, so as to prime the pumping device perfectly from the first use and thus ensure optimal delivery of the product.


Dosage
Apply the cream on the herpetic lesions and around the lesions, 5 times a day, each application being spaced at least 3 to 4 hours and without nighttime application.

Frequency of administration
Applications should be spread over the day, with an interval of at least 3 to 4 hours between two applications.
For example, apply the cream in the morning after breakfast, at noon after lunch, after tea, in the evening after dinner, in the evening before bedtime.

Duration of the treatment
The duration of treatment should not exceed 5 days, without medical advice.

Composition of ACTIVIR 5% TUBE CREAM 2G

The active substance is (per 100 g of cream) :
Aciclovir: 5.00 g

The other components are :
Propylene glycol, poloxamer 407, sodium laurilsulfate, cetostearyl alcohol, petrolatum, dimethicone 20, liquid paraffin, purified water, glycerol monostearate, macrogol stearate 100.

Precaution for use with ACTIVIR 5% 2G TUBE CREAM  

This medication contains propylene glycol and may cause skin irritation.
If there is no scarring after 5 days of treatment or worsening of your cold sore : Stop treatment and consult your doctor immediately.

In the event of a cold sore outbreak, a few hygienic precautions are necessary to protect those around you from the risk of virus transmission.
In addition to your treatment, to avoid transmission of the virus, you must comply with the following hygiene rules:

  • Avoid close contact, a kiss for example, with your entourage,
  • NEVER KISS A CHILD AT AGE,
  • Take the advice of your pharmacist or doctor in case of doubt about the nature of your injury,
  • Wash your hands thoroughly in case of contact with the lesion,
  • During treatment, in order not to spread the lesions, do not rub your eyes or your eyelids with your hands and if you wear contact lenses, never moisten them with your saliva,
  • Avoid touching or scratching the lesions.
  • In case of another localization of your herpes attack, never use this cream, take the advice of your doctor.

Presentation of ACTIVIR 5% 2G TUBE CREAM

This medication is in the form of a cream. 2 g tube.

Pharmacovigilance Report an adverse drug reaction(s)

Download PDF leaflet

NOTICE

ANSM - Last updated: 08/06/2017

Name of the medicinal product

ACTIVIR 5 PER CENT, cream

acyclovir

framed

Please read this leaflet carefully before you start using this medicine because it contains important information for you.

You should always use this medication exactly as prescribed in this leaflet or by your doctor or pharmacist.

· Keep this leaflet. You might need to read it again.

· Ask your pharmacist for advice or information.

· If you experience any of the side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. See section 4.

· You should contact your doctor if you experience no improvement or feel less well after 5 days.

Do not use this medication for children.

What is in this leaflet?

1. What is ACTIVIR 5 PERCENT, cream and in what cases is it used?

2. What should I know before using ACTIVIR 5 PER CENT, cream?

3. How to use ACTIVIR 5 PERCENT, cream?

4. What are the possible side effects?

5. How to keep ACTIVIR 5 PER CENT, cream?

6. Package contents and other information.

1. WHAT TO ACTIVATE 5 PER CENT, cream AND WHAT USE IS IT USED FOR?

Pharmacotherapeutic group: ANTIVIRALS - ATC code: D06BB03

This medication is indicated for the treatment of localized cold sores (also called "cold sore"), in adults and children over 6 years of age.

2. BEFORE YOU USE ACTIVITY 5%, cream?

Never use ACTIVIR 5 PERCENT, cream:

· in children under 6 years of age,

· if history of hypersensitivity to aciclovir, valaciclovir, propylene glycol or any of the other ingredients of this medicinal product mentioned in section 6.

If in doubt, you should seek the advice of your doctor or pharmacist.

Warnings and Precautions

Special warnings

DO NOT LEAVE THIS MEDICINE FOR CHILDREN.

Precautions for use

Precautions should be taken to avoid the accidental introduction of the cream into the eye.

To avoid local irritation, avoid applying cream to the mucous membranes (buccal and vaginal).

If you are severely immunosuppressed (eg, AIDS, transplant), see your doctor for treatment of any infection.

The propylene glycol excipient may cause skin irritation and cetostearyl alcohol may induce local skin reactions (eg contact dermatitis).

In case of absence of healing after 5 days of treatment or aggravation of your cold sore:

STOP TREATMENT AND SEEK YOUR DOCTOR IMMEDIATELY.

· In case of an outbreak of labial herpes, some hygiene precautions are necessary, to protect your entourage from the risk of transmission of the virus.

In addition to your treatment, to avoid transmission of the virus, you must respect the following hygiene rules:

· Avoid close contact, a kiss for example, with your entourage,

· NEVER ENGAGE A CHILD IN LOWER AGE,

· Take the advice of your pharmacist or doctor if you have any doubts about the nature of your lesion,

· Wash your hands thoroughly in case of contact with the lesion,

· During treatment, do not rub your eyes or eyelids with your hands and if you wear contact lenses, do not moisten them with your saliva,

· Avoid touching or scratching the lesions.

· In case of another localization of your herpes crisis, never use this cream, TAKE THE OPINION OF YOUR DOCTOR.

Children and Youth

Not applicable.

Other drugs and ACTIVIR 5 PER CENT, cream

Inform your doctor or pharmacist if you are taking, have recently taken or may take any other medicines.

ACTIVATE 5 PERCENT, cream with food, drinks and alcohol

Not applicable.

Pregnancy and breast feeding

Pregnancy

The use of aciclovir by the dermal route is possible in the pregnant woman in compliance with the indications.

If you discover that you are pregnant during treatment, tell your doctor as he alone can judge the need to continue.

feeding

If maternal pathology permits, breast-feeding is possible with this medication.

Generally, during pregnancy and breast-feeding, you should always seek advice from your doctor or pharmacist before taking any medication.

Sport

Not applicable.

Driving and using machines

There are no data on effects on the ability to drive and use machines.

ACTIVIR 5 PERCENT, cream contains: Cetostearyl alcohol, propylene glycol.

3. HOW TO USE ACTIVATE 5 PER CENT, cream?

Dosage

Apply the cream to the herpetic lesions and around the lesions, 5 times a day, each application being spaced at least 3 to 4 hours apart and without application at night.

Method and route of administration

Dermal.

Begin the first itching or burns before the vesicles appear, the treatment being more effective if it is started from the first symptoms announcing a herpes outbreak or cold sore.

Wash your hands thoroughly before and after each application of the cream on your cold sore to avoid transmitting the infection.

Apply the cream with your finger, overlapping largely around the lesion.

Close the tube or dispensing pump correctly after use.

How to use the pump:

It is recommended to perform at least 3 to 4 slow and complete pressures, so that the pumping device is fully primed as soon as it is first used and thus ensure optimal delivery of the product.

Frequency of Administration

The applications are to be distributed during the day, with an interval of at least 3 to 4 hours between two applications.

For example, apply the cream in the morning after breakfast, at lunchtime after lunch, after tasting, in the evening after dinner, in the evening before bedtime.

Duration of treatment

The duration of treatment should not exceed 5 days, without medical advice.

Use in children and adolescents

Do not use this cream in children under 6 years of age.

If you used more ACTIVIR 5 PERCENT, cream than you should:

Immediately consult your doctor or pharmacist.

If you forget to use ACTIVIR 5 PER CENT, cream:

Not applicable.

If you stop using ACTIVIR 5 PER CENT, cream:

Not applicable.

4. WHAT ARE POSSIBLE SIDE EFFECTS?

Like all medicines, this medicine may cause side effects, although not everybody gets them.

Due to the nature of the adverse events observed, it is not possible to determine which effects are related to the administration of the drug and which are related to the disease.

Uncommon side effects (affecting 1 to 10 users in 1,000): Tingling sensations or transient burns, dry skin, flaking of the skin, pruritus.

Uncommon side effects (affecting 1 to 10 users out of 10,000): Erythema, contact dermatitis.

Very rare side effects (affecting less than 1 user in 10 000): Cases of urticaria and angioedema (abrupt swelling of the face and neck of allergic origin) have been reported.

If you notice any side effects not listed in this leaflet, or if any of the side effects gets serious, contact your doctor or pharmacist.

Declaration of side effects

If you experience any side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Centers of Pharmacovigilance - Website: www.ansm.sante.fr

By reporting adverse reactions, you are helping to provide more information about the safety of the drug.

5. HOW TO STORE ACTIVATE 5 PER CENT, cream?

Keep this medicine out of the reach and sight of children.

Do not use this medicine after the expiry date which is stated on the package. The expiry date refers to the last day of that month.

Store at a temperature below 25 ° C. Do not refrigerate.

Do not throw any medicines into drains or rubbish. Ask your pharmacist to remove any medications you are no longer using. These measures will help protect the environment.

6. PACKAGE CONTENTS AND OTHER INFORMATION

What ACTIVIR 5 PERCENT, cream contains

· The active substance is:

aciclovir ................................................. .................................................. ............................. 5.00 g

· The other components are:

Propylene glycol, poloxamer 407, sodium lauryl sulfate, cetostearyl alcohol, petroleum jelly, dimethicone 20, liquid paraffin, purified water, glycerol monostearate, macrogol stearate 100.

What is ACTIVIR 5 PER CENT, cream and contents of the pack

This medication is in the form of a cream. Tube of 2 g.

Marketing Authorization Holder

GLAXOSMITHKLINE HEALTH GRAND PUBLIC

100, ROUTE DE VERSAILLES

CS 80001

78164 MARLY LE ROI CEDEX

Marketing Authorization Operator

GLAXOSMITHKLINE HEALTH GRAND PUBLIC

100, ROUTE DE VERSAILLES

CS 80001

78164 MARLY LE ROI CEDEX

Maker

GLAXO WELLCOME OPERATIONS

HAMIRE ROAD

BARNARD CASTLE

COUNTY DURHAM DL 12 8 DT

UK

Names of the medicinal product in the Member States of the European Economic Area

Not applicable.

The last date on which this leaflet was revised is:

[to be completed later by the holder]

Detailed information on this medicine is available on the ANSM website (France).

Other

Health Education Council

Cold sores or cold sores are due to an infection caused by a virus called Herpes Simplex. After a primary infection, the virus persists in the body without causing symptoms.

During an event such as fatigue, menstruation, fever, emotion or sun exposure, the virus can sometimes be "reactivated" and cause the appearance of vesicles (blistering) in a bouquet around the lips, called "cold sores". These vesicles are contagious until the appearance of scabs, sign of scarring.

There are signs before riders located at the usual location of the lesion, which usually result in a burning sensation and / or tingling.

These signs are important to know:

· it is as soon as they appear that the treatment must be started which prevents viral multiplication and makes it possible to prevent or limit the development of the cold sore,

· it is also as soon as they appear that you must respect the hygiene rules given to you in the precautions of use, in order to reduce the risk of transmission of the virus.

On the other hand, aciclovir can not act on viruses that persist latently in the body and aciclovir does not prevent the occurrence of recurrences after the interruption of treatment.

VIDAL OF THE FAMILY

ACTIVIR

Local antiherpetics

acyclovir

. Presentations . Composition . Indications . Contraindications . Warning . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS (summary)

ACTIVITY 5%: cream; 2 g tube with metering pump.
-

ACTIVITY 5%: cream; 2 g tube.
-

Laboratory GlaxoSmithKline Consumer Healthcare

COMPOSITION (summary)
p 100 g
acyclovir 5 g
Propylene glycol +

INDICATIONS (summary)
This medicine contains an antiviral . It blocks the multiplication of the virus herpes within infected cells.
It is used in the treatment of cold sores (also called " cold sores").
CONTRAINDICATIONS (summary)
This cream should not be used in the following cases:
  • child under 6 years of age,
  • herpes on the eye or inside the mouth or vagina.
WARNING (Contents)
This medication is available without a prescription and is to be used on the advice of your pharmacist. report any history of an allergic reaction to a drug containing acyclovir or valaciclovir. Do not use it for herpes lesions other than on the lips.
This medicine treats herpes outbreaks but does not eliminate the virus from the body. It does not prevent the occurrence of other crises.
Ultraviolet stimulates herpes outbreaks. Avoid exposure to strong sunlight or UV light, or apply a full screen in sufficient quantity and renewed.
PREGNANCY AND BREAST-FEEDING (summary)
This cream can be used during pregnancy or lactation.
DIRECTIONS FOR USE AND DOSAGE (summary)
Treatment should be started from the first symptoms (tingling, itching) that indicate a cold outbreak of cold sores.
The cream should be applied by overflowing around the lesions.

Usual dosage:

  • Adult and child over 6 years: 5 applications per day, spacing applications at least 3 or 4 hours.
The duration of treatment should not exceed 5 days without medical advice.
TIPS (summary)
To prime the metering pump system, perform at least 3 or 4 slow and full pressures on first use.
Herpes is a contagious disease. Wash your hands thoroughly after application of the cream or in case of contact with the lesions; especially, avoid touching your eyes with contaminated fingers. The risk of contagion is maximal at the moment when the vesicles appear (small blisters under the skin).
This medicinal product may be freely available in certain pharmacies; nevertheless, do not hesitate to ask your pharmacist for advice.
POSSIBLE ADVERSE EFFECTS (summary)
Tingling, local burning sensation, redness, dryness of the skin.
Rarely: contact eczema , allergic reaction.


GLOSSARY (summary)


antiviral
Medication capable of fighting viruses.


eczema
Skin disease manifested by pimples and itching. Eczema may be due to contact with an allergic substance (contact eczema) or be linked to a genetic predisposition (atopic eczema).


herpes
  • Viral disease due mainly to Herpes simplex 1 and 2 viruses. It manifests itself during outbreaks by a painful rash of fine vesicles. Between the flares, the virus remains present in the nervous ganglia. Type 1 virus is more likely to give lesions around the mouth, whereas type 2 virus preferably affects the genitals.
  • A family of viruses (herpesvirus) which includes Herpes simplex virus (HSV 1 and 2), varicella zoster virus (VZV), cytomegalovirus (CMV) and Epstein-Barr virus (EBV) of infectious mononucleosis .


allergic reaction
Reaction due to hypersensitivity of the organism to a drug. Allergic reactions can take a wide variety of aspects: urticaria, angioedema, eczema, eruption of pimples resembling measles, etc. Anaphylactic shock is a generalized allergic reaction that causes discomfort due to a sudden drop in blood pressure.


symptoms
Trouble felt by a person with an illness. The same symptom can translate different diseases and the same disease does not necessarily give the same symptoms in all the patients.


virus
A microscopic organism that penetrates the cells of the host, where it reproduces. Much smaller than bacteria, viruses are insensitive to antibiotics. They can sometimes be destroyed by antiviral substances.

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