Pevaryl 1% Cream, a leading topical antifungal, effectively relieves fungal skin infections. Available in pharmacies for convenient, targeted application.
Pevaryl 1% Cream is an antifungal agent from the imidazole family, specially formulated to treat fungal skin infections. This product acts effectively against fungal infections, relieving the itching and discomfort associated with skin infections. Thanks to its active ingredient, econazole nitrate, this cream is designed to eliminate the fungi responsible for skin ailments. It is ideal for treating candidiasis, including genital and submammary intertrigiosis, as well as dermatophytes of the glabrous skin.
Pevaryl 1% is particularly indicated for skin infections in areas where humidity favors the proliferation of fungi, such as skin folds. By acting directly on the affected area, this cream helps reduce inflammation and redness, and prevents recurrence of infections thanks to its powerful, long-lasting antifungal action.
Used regularly, Pevaryl 1% significantly improves skin condition by progressively eliminating the fungi responsible. Its topical application enables rapid, targeted absorption, limiting the risk of undesirable effects while providing immediate skin comfort. With its creamy texture, Pevaryl is easy to apply, ensuring effective penetration into the affected areas for optimal healing.
This cream is also suitable for patients who need additional treatment to prevent recurrence in particularly sensitive areas such as nails and skin folds. Thanks to its moisturizing and soothing properties, it helps restore the skin's natural balance, while protecting it from external aggression.
In addition to its antifungal properties, Pevaryl 1% Cream helps improve daily comfort by facilitating the care routine for affected areas. Its easy-to-apply formula is ideal for users looking for a localized care product. The cream's light, creamy texture promotes even, pleasant application, without leaving an oily residue on the skin, enabling users to continue their activities without discomfort.
The versatility of Pevaryl 1% Cream makes it a preferred choice for those seeking a skin care solution for different everyday situations. Whether it's to soothe a sensitive skin area or to maintain optimal skin hygiene, this antifungal cream can easily be integrated into a personal skin care routine. Designed for everyday use, the product is distinguished by its ease of application and pleasant texture, enabling targeted care that doesn't disrupt daily habits or comfort.
To meet the needs of users faced with recurring skin discomfort, Pevaryl 1% Crème offers a quick and easy-to-use solution that can be easily integrated into everyday life. Its compact tube format makes it a practical ally for use in all circumstances. What's more, its targeted, localized action is compatible with other topical treatments, enabling effective overall skin care.
We also offer Pevaryl 1% Powder Powder bottle 30 g at the best price in our online pharmacy.
Apply Pevaryl 1% Cream to the affected area 2-3 times a day. Before each application, clean and dry the area well to promote absorption. Massage gently until completely absorbed. This treatment should be followed for 2 to 4 weeks, as recommended by your doctor or pharmacist.
Give your opinion on the advice for use and dosage of Pevaryl 1% Cream with our partner Verified opinions after your purchase.
Precautions for use:
Econazole Nitrate, Ethylene Glycol Stearates, Liquid Paraffin, Unsaturated Polyglycolysed Glycerides, Benzoic Acid, Butylated Hydroxyanisole, Purified Water.
Presentation:
Pevaryl 1% Cream comes in a 30 g tube, ideal for topical application and convenient to take along.
Pharmacovigilance Report an adverse drug reaction(s)
NOTICE
ANSM - Updated on : 09/02/2022
Product name
PEVARYL 1%, cream
Deconazole nitrate
Box
Please read this leaflet carefully before using this medicine, as it contains important information for you.
You must always use this medicine in strict accordance with the information provided in this leaflet or by your doctor or pharmacist.
- Keep this leaflet. You may need to read it again.
- Ask your pharmacist for advice and information.
- If you experience any side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. See section 4.
- You should contact your doctor if you do not feel any improvement or if you feel less well.
What does this leaflet contain?
1. What is PEVARYL 1% cream and what is it used for?
2. What do I need to know before using PEVARYL 1% cream?
3. How do I use PEVARYL 1% cream?
4. What are the possible side effects?
5. How should PEVARYL 1% cream be stored?
6. Package contents and other information.
1. WHAT IS PEVARYL 1% cream AND WHAT IS IT USED FOR?
Pharmacotherapeutic class: TOPICAL ANTIFUNGAL - IMIDAZOLES AND TRIAZOLES DERIVATIVES, ATC code: D01AC03.
This medicine contains an antifungal agent (active against fungi) of the imidazole family.
It is indicated for the treatment of certain skin mycoses (skin disorders caused by fungi).
Candidiasis :
- Treatment of non-macerated fold mycoses: genital, submammary, interdigital intertrigo, etc.
- Treatment of nail mycoses: onyxis, perionyxis. Associated systemic antifungal treatment is required.
In the case of wool fold infections, oral antifungal treatment is required to treat a possible digestive and/or vaginal focus, and thus avoid any recurrence.
Dermatophytes :
- Treatment :
o Dermatophytes of hairless skin.
o Non-macerated genital and crural intertrigos.
- Treatment of ringworm. Associated systemic antifungal treatment is required.
Erythrasma.
2. WHAT DO I HAVE TO KNOW BEFORE USING PEVARYL 1% cream?
Never use PEVARYL 1% cream:
- if you are allergic to deconazole nitrate or any of the other ingredients listed in section 6.
Warnings and precautions
Talk to your doctor or pharmacist before using PEVARYL 1% cream.
Be careful with PEVARYL 1%, cream:
- in children,
- on large areas of skin,
- on damaged skin,
- in situations where the local docclusion phenomenon may recur (e.g. elderly subjects, bedsores, submammary lesions).
In such cases, it is essential to follow the recommendations and dosage indicated in the package leaflet, as the drug penetrates the skin more easily.
- You should stop using this product if you develop an allergy (recognizable by redness or pimples) or irritation.
- Do not apply to the eyes, nose or mucous membranes in general.
- Candidiasis: do not use soaps with acidic pH (pH favors Candida multiplication).
- This product contains benzoic acid and may cause local irritation. Benzoic acid may increase the risk of dicterus (yellowing of the skin and eyes) in neonates (up to 4 weeks of age).
- This medicine contains butylated hydroxyanisole (E320) and may cause local skin reactions (e.g. contact dermatitis) or irritation of the eyes and mucous membranes.
Children and adolescents
Not applicable.
Other medicinal products and PEVARYL 1%, cream
Tell your doctor or pharmacist if you are taking, have recently taken or may take any other medicines.
Tell your doctor if you are taking a blood-thinning medication, the antivitamins K (such as acenocoumarol, fluindione, warfarin), as PEVARYL may modify the action of antivitamins K in some people. You should therefore monitor your INR (blood tests) frequently. Depending on your situation, your doctor may also decide to modify the dose of your antivitamin K during or after treatment with PEVARYL.
PEVARYL 1% cream with food and drink
Not applicable.
Pregnancy and breast-feeding
In view of the limited but possible systemic passage of PEVARYL after dermal application, and in the light of clinical experience, PEVARYL 1% cream is not recommended for use during pregnancy or while breast-feeding, without the advice of your doctor.
Do not apply to the breasts while breast-feeding.
If you are pregnant or breastfeeding, think you may be pregnant or are planning to become pregnant, ask your doctor or pharmacist for advice before taking this medicine.
Driving and use of machinery
Not applicable.
PEVARYL 1% cream contains benzoic acid and butylated hydroxyanisole (E320).
3. HOW DO I USE PEVARYL 1% cream?
Always use this medicine exactly as instructed in this leaflet or as directed by your doctor or pharmacist. Check with your doctor or pharmacist if in doubt.
Dosage
Apply PEVARYL to the skin 2 to 3 times a day, up to a maximum of 3 applications per day. Treatment should be continued for 2 to 4 weeks.
Method of administration
For EXTERNAL USE ONLY: applied directly to the skin.
1. Clean affected area and surrounding area, then dry skin thoroughly before application.
2. Massage gently and evenly until the cream is completely absorbed.
Regular use of this medication throughout the treatment period is crucial to its success.
If there is no improvement, consult a doctor.
If you have accidentally swallowed PEVARYL 1% cream :
Consult a physician for treatment appropriate to the side effects that may occur.
If you accidentally squirt PEVARYL 1% cream into your eyes :
Wash with clean water or saline solution.
If this does not help, consult a physician.
If you have used more PEVARYL 1% cream than you should have
Not applicable.
If you forget to use PEVARYL 1%, cream
Not applicable.
If you stop using PEVARYL 1%, cream
Not applicable.
If you have any further questions about the use of this medicine, ask your doctor or pharmacist.
4. WHAT ARE THE POSSIBLE SIDE EFFECTS?
Like all medicines, this drug may cause undesirable effects, but they do not occur systematically in everyone.
Common side effects (1 to 10 out of 100 users) are :
- itching,
- burning sensation,
- pain at the application site.
Uncommon adverse reactions (1 to 10 out of 1,000 users) are :
- redness,
- discomfort
- swelling at the application site.
Undesirable effects for which the frequency is not determined are :
- allergy (hypersensitivity),
- swelling of the throat or face (angioedema),
- skin rash,
- urticaria,
- blisters,
- peeling skin (exfoliation).
Reporting side effects
If you experience any side effects, please tell your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: Agence nationale de sécurité du médicament et des produits de santé (ANSM) and the network of Regional Pharmacovigilance Centers.
By reporting adverse reactions, you are helping to provide more information on drug safety.
5. HOW SHOULD PEVARYL 1% cream be used?
Keep out of sight and reach of children.
Do not use this medicine after the expiration date indicated on the box. The expiration date refers to the last day of that month.
Store at a temperature not exceeding 25°C.
Do not dispose of any medicine down the drain or in the household waste. Ask your pharmacist to dispose of any medicines you no longer use. These measures will help protect the environment.
6. CONTENTS AND OTHER INFORMATION
What PEVARYL 1% cream contains
- The active substance is :
Deconazole nitrate............................................................................................................ 1.0 g
per 100 g of cream.
- Other ingredients are :
Ethylene glycol stearates and macrogols 300 and 1500 (Tefose 63), liquid kerosene, unsaturated polyglycolysed glycerides (Labrafil M 1944 CS), benzoic acid, butylated hydroxyanisole (E320), purified water.
What PEVARYL 1% cream is and what it contains
This medicine comes in the form of a cream. Tube of 30 g.
Marketing authorization holder
KARO PHARMA AKTIEBOLAG
BOX 16184
103 24 STOCKHOLM
SWEDEN
Marketing authorization holder
ALLOGA FRANCE
ZAC DE CHAPOTIN SUD
69970 CHAPONNAY
Manufacturer
LUSOMEDICAMENTA - SOCIEDADE TECNICA FARMACEUTICA, S.A.
ESTRADA CONSIGLIERI PEDROSO 69 B, QUELUZ DE BAIXO,
2730-055 BARCARENA,
PORTUGAL.
Product names in member states of the European Economic Area
Not applicable.
The last date on which this leaflet was revised was :
November 2021
Other
Detailed information on this drug is available on the ANSM (France) website.
Ce médicament d'action locale contient un antifongique de la famille des imidazolés.
Il est utilisé dans le traitement de certaines maladies de la peau, des ongles et des muqueuses, dues à des champignons microscopiques (mycoses) : candidose, dermatophyties...
La solution pour application locale est réservée au traitement du pityriasis versicolor.
Les prix mentionnés ne tiennent pas compte des « honoraires de dispensation » du pharmacien.
| p 100 g (crème) | p 100 g (émulsion) | |
| Éconazole nitrate | 1 g | 1 g |
| Acide benzoïque | + | + |
| Butylhydroxyanisole | + | + |
| Butylhydroxytoluène | + | + |
| p 100 g (poudre) | p 100 g (solution) | |
| Éconazole nitrate | 1 g | 1 g |
| Propylèneglycol | + |
Ce médicament ne doit pas être utilisé en cas d'allergie aux antifongiques de la famille des imidazolés.
Évitez d'utiliser ce médicament de manière prolongée et sur des surfaces étendues ou profondément lésées, notamment chez l'enfant, sans l'avis de votre pharmacien ou de votre médecin.
Rincez abondamment en cas de contact accidentel avec les yeux.
Un traitement prolongé par éconazole peut interagir avec certains anticoagulants oraux (antivitamine K) et nécessiter un contrôle plus fréquent de l'INR.
Les médicaments contenant de l’éconazole peuvent être utilisés pendant la grossesse après avis de votre médecin ou de votre pharmacien.
La possibilité d'un effet du médicament chez le nourrisson est très improbable. Il peut être utilisé chez la femme qui allaite.
Le médicament doit être appliqué après lavage et séchage soigneux de la zone à traiter. La forme utilisée (crème, émulsion, solution, poudre) et la durée du traitement varient selon les cas. Suivre la prescription de votre médecin ou les conseils de votre pharmacien.
Crème, solution, émulsion : appliquer avec le bout des doigts, une petite quantité de produit ayant été déposé dans le creux de la main ou directement sur les lésions, puis masser pour faire pénétrer. Dans les plis de la peau, la crème doit être appliquée en petite quantité pour limiter le risque de macération.
Poudre : appliquer directement sur la zone à traiter ; elle peut être également utilisée dans les chaussures, source fréquente de recontamination en cas de mycose des pieds.
2 ou 3 applications par jour, pendant 2 à 4 semaines.
Dans le traitement du pityriasis versicolor : 2 applications par jour, pendant 2 semaines.
En cas de candidose, évitez d'utiliser des savons acides : ils favorisent la multiplication des champignons.
En cas de lésion importante des ongles des orteils, un meulage préalable par un pédicure facilite l'action du médicament.
Une transpiration excessive contribue au développement des lésions dues à des champignons. Le port de chaussettes en fibre naturelle (coton, laine) est recommandé. La même paire de chaussures ne doit pas être portée deux jours de suite.
Fréquents (1 à 10 % des personnes) : démangeaisons, sensation de brûlure, douleur au site d'application.
Peu fréquents (moins de 1 personne sur 100) : rougeur, gêne, gonflement au site d'application.
Fréquence indéterminée : réaction allergique (éruption cutanée, urticaire, œdème de Quincke...).
Réaction cutanée (démangeaisons, boutons, gonflement) ou malaise général apparaissant après un contact avec une substance particulière, l'utilisation d'un médicament ou l'ingestion d'un aliment. Les principales formes d'allergie sont l'eczéma, l'urticaire, l'asthme, l'œdème de Quincke et le choc allergique (choc anaphylactique). L'allergie alimentaire peut également se traduire par des troubles digestifs.
Médicament qui détruit les champignons et levures microscopiques. Ceux-ci peuvent être présents sur la peau ou les muqueuses (tube digestif ou organes génitaux). La levure la plus courante est le Candida albicans.
Multiplication anormale d'une levure microscopique, Candida albicans le plus souvent. Il s'agit d'une complication fréquente et bénigne des traitements antibiotiques. Les principaux symptômes sont des troubles digestifs, une coloration marron ou noire de la langue, des taches blanches sur le palais ou la langue (muguet), des démangeaisons ou des brûlures de la vulve ou du gland.
Infection de la peau ou des ongles par un champignon microscopique (dermatophyte).
Apparition de boutons ou de plaques sur la peau. Ces lésions peuvent être dues à un aliment, à un médicament, et traduire une allergie ou un effet toxique. De nombreux virus peuvent également provoquer des éruptions de boutons : celles de la rubéole, de la roséole et de la rougeole sont les plus connues.
La fréquence d'un effet indésirable est décrite dans les documents officiels de la manière suivante :
Famille de médicaments qui regroupe des antifongiques, des antibiotiques et des antiparasitaires.
Mode de préparation de certaines tisanes ; ce procédé permet d'extraire les substances contenues dans les plantes en les faisant tremper de façon prolongée dans de l'eau froide. Cette technique diffère de l'infusion ou de la décoction.
Tissu (membrane) qui tapisse les cavités et les conduits du corps communiquant avec l'extérieur (tube digestif, appareil respiratoire, voies urinaires, etc.).
Affection due à des champignons microscopiques, favorisée par la prise d'antibiotiques.
Consultez l'article : Mycose de la peau, Mycose vaginale.
Enfant de un à 30 mois. Un enfant de moins de un mois est un nouveau-né.
Infection de la peau due à un champignon microscopique. Elle se manifeste par des taches qui paraissent brunes sur une peau blanche et blanches sur une peau bronzée. Après traitement, seule une exposition au soleil permet de faire disparaître les taches.
Réaction allergique touchant généralement le visage. L'œdème de Quincke se traduit par un gonflement parfois spectaculaire. Les paupières sont souvent les premières touchées. Dans les rares cas où l'œdème touche la gorge, des troubles respiratoires peuvent survenir et un traitement urgent est nécessaire.
Réaction due à l'hypersensibilité de l'organisme à un médicament. Les réactions allergiques peuvent prendre des aspects très variés : urticaire, œdème de Quincke, eczéma, éruption de boutons rappelant la rougeole, etc. Le choc anaphylactique est une réaction allergique généralisée qui provoque un malaise par chute brutale de la tension artérielle.
Consultez l'article : Peut-on être allergique aux médicaments ?
Éruption de boutons sur la peau, dont l'origine est le plus souvent allergique. Les boutons ressemblent à des piqûres d'orties et leur couleur varie du rose pâle au rouge. L'urticaire peut apparaître ou disparaître en quelques minutes, et provoque d'intenses démangeaisons ; elle peut être localisée ou généralisée à la totalité de la surface cutanée.
Dermatophytes, which cause mycosis, are ubiquitous filamentous fungi belonging to the genera Microsporum, Trichophyton and Epidermophyton. Well adapted to parasitic life, they have a strong affinity for keratin and cause various skin lesions in humans and animals known as dermatophytoses or dermatophyties. Dermatophytoses are the most common skin mycoses in humans. They cause superficial lesions on hairless skin, the palms…
Read the article on the blogCandida Albicans is a fungus that lives on the human body. It is found in the mouth, the intestines and on the skin. In fact, Candida Albicans is a yeast that can cause infections when it is out of balance with the healthy bacteria in the body. These common infections, such as thrush or vaginal fungus, are treated with antifungal…
Read the article on the blogIntertrigo is an inflammation of the skin that occurs in the folds of the skin, a condition that affects a large number of people throughout the world. How can it be prevented? What are the best methods treatment methods? Faced with these questions, many people feel overwhelmed. Why does this condition exist? Who is at risk? Let's take a detailed…
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