Cleanance Comedomed+ is an anti-blemish cream formulated by the Avène dermatological laboratory; it has been designed from the outset to target pimples and blackheads. It is perfectly suited for blemish-prone and acne-prone skin .
Avène Cleanance Comedomed+ Intensive Treatment is a dermatological innovation specially developed for oily, acne-prone skin. Tested on more than 4,600 patients, it directly targets microcomedones—the root cause of blemishes—to reduce pimples, blackheads, and post-acne marks. Thanks to a formula enriched with patented Comedoclastin™ and niacinamide, this treatment acts quickly and prevents the reappearance of blemishes, with proven anti-recurrence efficacy lasting up to 1 year. Its lightweight gel-cream texture leaves the skin clear, soothed, and long-lasting hydrated.
One of the key benefits of this treatment is its ability to significantly reduce blackheads. Its 25% concentration of Comedoclastin™ reduces sebum production, preventing pores from becoming clogged.
Combined with niacinamide, it limits the proliferation of microcomedones andslows the development of new blemishes. At the same time, its anti-inflammatory effect helps calm redness, reduce the size of pimples, and soothe sensitive areas. This dual purifying and soothing action helps maintain a more even skin texture that is visibly clearer and more radiant.
This treatment also acts as a sebum regulator, limiting excess shine and reducing the environment conducive to the growth of acne-causing bacteria. By providing long-lasting control over sebum secretion, it prevents clogged pores and helps prevent the appearance of new breakouts. Above all, it stands out for its unique ability to maintain anti-acne results for up to 12 months after treatment ends, offering long-lasting protection against recurrence.
Unlike many drying anti-acne treatments, Cleanance Comedomed+ provides continuous hydration for 24 hours. Its fresh, lightweight gel-cream texture respects the skin’s moisture balance and prevents any feeling of tightness. Enriched with Avène Thermal Spring Water, this treatment soothes irritation and strengthens the skin’s tolerance, even in skin weakened by medicated acne treatments.
This product is non-comedogenic and formulated for high dermatological tolerance, making it perfectly suited for acne-prone skin. It does not promote the formation of new breakouts and can be used safely by teenagers as young as 9 years old as well as adults. Its minimalist formula, free of occlusive agents, ensures effective care without aggravating clogged pores.
Cleanance Comedomed+ easily fits into a daily routine: apply it morning and night to clean, dry skin. Visible results within 5 hours have been demonstrated starting with the very first application. After 14 days, clinical results show up to a 54% reduction in blackheads, a 39% reduction in pimples, and a 43% reduction in post-acne marks. When used regularly, this treatment helps maintain clear, balanced skin that is long-term protected against breakouts.
For best results, it is recommended to thoroughly cleanse the skin before applying the cream and to incorporate it into a skincare routine tailored to the specific needs of acne-prone skin.
We also offerBioderma Sébium Global Cover Intense Purifying Tinted Treatment at the best price in our online pharmacy.
Apply this treatment twice daily, morning and evening, to clean, dry skin. Use it after cleansing your face with a cleanser from the Cleanance line. It can be used alone or in combination with a prescription acne treatment, depending on your needs and your dermatologist’s recommendations.
Share your feedback on the usage instructions and dosage of Avène Cleanance Comedomed+ Intensive Anti-Blemish Treatment with our partner Avis Vérifiés after your purchase.
Precautions for Use
Avene thermal spring water (avene aqua). Isopropyl alcohol. PEG-6. Glycerin. Niacinamide. Silybum marianum fruit extract. Silica. Polyacrylate-13. Polyisobutene. Polysorbate 20. Sorbitan isostearate. Water (aqua)
Product Details
30 ml pump bottle—convenient and hygienic—available at the best price in our online pharmacy.
In naturopathy, acne and skin imperfections are not considered merely superficial problems but are often seen as reflections of an internal imbalance. To support the effectiveness of this treatment, it’s a good idea to adopt a diet low in refined sugars and rich in colorful vegetables, which are sources of protective antioxidants. Omega-3s (found in flaxseeds, chia seeds, or canola oil) help reduce skin inflammation.
Caring for your liver with regular courses of detoxifying herbs such as Desmodium or milk thistle can also support the body’s detoxification process and help limit excess sebum production. Finally, paying attention to your sleep and engaging in regular physical activity helps regulate hormonal balance, which is often a factor in the development of skin imperfections.
This skincare routine thus becomes an effective ally for healthy skin, to be combined with a holistic, natural lifestyle to achieve visible and long-lasting results.
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