BiCirkan 60 tablets Venous circulation



Order the drug without prescription BiCirkan in pharmacy. It is a venotonic and a vasosculoprotective which causes a vasoconstriction, increases the resistance of the vessels and decreases their permeability. It is indicated in disorders of the venous circulation and the hemorrhoidal crisis .

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Used for : hemorrhoidal crisis, venous circulation

contains: holly, ascorbic acid

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BiCirkan 60 tablets to improve venous circulation

For warnings, precautions for use and contraindications, please consult the instructions for use.

Description of BiCirkan 60 tablets Venous circulation

BiCirkan is a veinotonic and a vasosculoprotective agent which causes vasoconstriction, increases the resistance of the vessels and decreases their permeability .

A veinotonic is a drug recognized for its effectiveness against more or less serious circulatory problems located on the lower limbs such as hemorrhoids, heavy legs or phlebitis. It is a treatment for heavy legs. It is often extracted from plants.

Learn more about the different pathologies of venous circulation .

  • Heaviness in the legs or calves is a particular feeling of heaviness in the legs, generally greater at the end of the day, in case of high heat, when standing or sitting for a long time, or when the calf is compressed in clothes or shoes that are too tight.
  • Phlebalgia is pain specific to a venous path and can result in stitches in the path of the veins.
  • Lower extremity cramps appear in 30% of venous diseases and are characterized by a lasting and abnormal contraction of a leg muscle, reflecting poor drainage of oxygen-depleted blood.
  • Impatience is a feeling of numbness defined as an urge to move your legs during prolonged stationary stations, forcing you to get up.

Description of BiCirkan

It is indicated in disorders of venous circulation and hemorrhoidal crisis .

In case of chronic pathology, it is possible to combine this treatment with L28 LEHNING oral drops , homeopathic treatment for venous circulation disorders (varicose veins, varicose ulcers, hemorrhoids).

How to use BiCirkan

2 tablets per day in 2 taken with meals, i.e. 1 tablet in the morning and 1 tablet at noon

Some tips to improve your daily life :

  • Pass your legs under cold water . Cold water will " energize " your veins by avoiding venous stagnation.
  • Massage your legs ! In addition to being pleasant on a daily basis, massage also facilitates blood circulation . Massage your legs from the bottom up, in order to make the blood go up in the legs! Guaranteed effect!
  • Elevate your legs as much as possible throughout the day.
  • Avoid sitting or standing stations that do not encourage the rise of blood in the legs.

Composition of BiCirkan

Dry extract of holly, hesperidin methylchalcone, ascorbic acid
Excipients: hypromellose, microcrystalline cellulose, copovidone, crospovidone, talc, anhydrous colloidal silica, magnesium stearate. Coating: hypromellose, ethylcellulose, triethyl citrate, titanium dioxide (E 171), cochineal red lacquer (E 124)
Excipient with known effect: cochineal red lacquer

Precautions for using BiCirkan

Contraindications : Allergy to one of the constituents

Oral use

Read the instructions carefully

BiCirkan overview

Box of 60 film-coated tablets

Drug warnings

Please note, the non-prescription drug Bicirkan is not a product like any other. Read the instructions for the Bicirkan tablet carefully before ordering. Keep medicines out of the reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Beware of incompatibilities on your current treatments.

  • Please inform your online pharmacist of the treatments in progress in order to identify any incompatibilities. The order validation form contains a personalized message field provided for this purpose.
  • Click here to find the package leaflet for this medication on the website of the National Agency for the Safety of Medicines and Health Products.
  • Pharmacovigilance: Declare one or more undesirable effect (s) linked to the use of a Bicirkan drug.



Vasculoprotective and veinotonic

small holly, hesperidin methylchalcone, ascorbic acid

. Presentations . Composition . Indications . Warning . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon


BICIRKAN: tablet (pink); box of 30.

BICIRKAN: tablet (pink); box of 60.

Laboratory Pierre Fabre Medicine

p cp
Small holly, dry extract 80 mg
Hesperidin methylchalcone 200 mg
Ascorbic acid (vitamin C) 400 mg

It is a vascular protector and a veinotonic . It facilitates the circulation of the blood in the veins and combats the alteration of the capillary vessels .
It is used in the symptomatic treatment:
WARNING (Contents)
This drug is insufficient to prevent the risk of phlebitis in patients bedridden or plastered.
The treatment of venous insufficiency is based on specific measures such as the wearing of compression stockings.
Pains, anal bleeding that persist despite treatment may be due to a disease other than hemorrhoids and require medical advice. Similarly, any anal bleeding occurring in a person over 50 years of age should be the subject of a medical consultation.
The effect of this medication during pregnancy or lactation is not well known. The assessment of the possible risk associated with its use is individual: ask your pharmacist or doctor for advice.
This medication should be taken with a glass of water at the beginning of meals.

Usual dosage:

1 tablet in the morning and 1 tablet at noon.
TIPS (summary)
Regular physical activity and elevation of the foot of the bed facilitate the venous and lymphatic circulation.
Chronic constipation and excessive thrust are the main factors triggering hemorrhoid seizures. Diets high in dietary fiber, abundant drinks and regular physical exercise limit the risk.
Diarrhea, sometimes severe, requiring discontinuation of treatment.
Nausea, stomach pain.
Rarely: rash.

GLOSSARY (summary)

Abnormal dilation of a vein of the anus or rectum developing either externally or internally. It may cause bleeding.

Painful sensations in the legs. They manifest themselves, usually during bedtime, by a feeling of discomfort, an irrepressible need to move their legs.

venous insufficiency
Incapacity of the veins of the legs to bring the blood back to the heart.

The lymph, a colorless liquid that circulates in specific vessels and whose accumulation causes edema.

Inflammation of a deep vein with formation of a blood clot, usually affecting the legs. The severity of the phlebitis is related to the possibility of displacement of the clot which can migrate to the heart and then obstruct an artery of the lungs (pulmonary embolism). A paraphlebite, or superficial phlebitis, is the inflammation of a superficial vein; it is much less worrying.

symptomatic treatment
Treatment that suppresses or alleviates the symptoms of a disease without addressing its cause.

capillary vessels
Blood vessels thinner than hair (hence their name) that irrigate the cells.

Blood vessels: arteries and veins.

Refers to a drug that has the property of increasing the tone of the wall.

Click here to find the record of this drug on the website of the National Agency for the Safety of Medicines and Health Products.

Pharmacovigilance : Report an adverse effect (s) related to the use of a drug


ANSM - Last updated: 19/04/2017

Name of the medicinal product

BICIRKAN, film-coated tablet

Dry extract of Petit houx / hesperidin methyl chalcone / ascorbic acid


Please read this leaflet carefully before you start using this medicine because it contains important information for you.

You should always use this medication exactly as prescribed in this leaflet or by your doctor or pharmacist.

· Keep this leaflet. You might need to read it again.

· Ask your pharmacist for advice or information.

· If you experience any of the side effects, talk to your doctor, or your pharmacist. This also applies to any side effects not mentioned in this leaflet. See section 4.

· You should contact your doctor if you experience no improvement or feel worse after a few days in case of a hemorrhoidal attack or after 14 days in case of venous circulation problems.

Do not use this medication for children.

What is in this leaflet?

1. What is BICIRKAN, film-coated tablet and in which case it is used?

2. What information should I take before taking BICIRKAN film-coated tablets?

3. How to take BICIRKAN, film-coated tablet?

4. What are the possible side effects?

5. How to store BICIRKAN film-coated tablets?

6. Package contents and other information.

1. WHAT IS BICIRKAN, film-coated tablet AND WHAT IT IS USED FOR?

Pharmacotherapeutic group: ATC code

What is BICIRKAN, film-coated tablet?

BICIRKAN is a combination of three active substances: small holly extract, hesperidin methyl chalcone and ascorbic acid (vitamin C).

BICIRKAN belongs to a group of medicines acting on the permeability of the capillary vessels (cardiovascular system).

This drug is a veinotonic and a vasculoprotective (it increases the tone of the veins and the resistance of the vessels and decreases their permeability).

In which cases is it used?

BICIRKAN is used in adults to treat:

· disorders of the venous circulation: heavy legs, swollen, painful, painful sensations (so-called impatience of the first decubitus) at bedtime.

· the functional signs related to the hemorrhoid crisis (dilation and inflammation of the veins in the anus).

2. BEFORE YOU TAKE BICIRKAN, film-coated tablet?

Do not take BICIRKAN, film-coated tablets:

· If you are allergic (hypersensitive) to the active ingredients (small holly solids, hesperidin methyl chalcone and / or ascorbic acid) or to any of the other ingredients of this medication mentioned in section 6 .

· If you have iron storage problems (thalassemia, hemochromatosis, sideroblastic anemia) due to the presence of ascorbic acid (vitamin C) in the composition of this drug.

Warnings and Precautions

Special warnings

· In case of diarrhea: stop your treatment and tell your doctor (see section 4 What are the possible side effects?)

· Venous circulation disorders: If the discomfort and / or fragility of the vessels does not improve after 15 days of treatment, consult your doctor.

· Hemorrhoidal attack: The administration of this product does not provide specific treatment for other anal diseases. If hemorrhoidal problems persist after a few days of treatment, it is essential to consult your doctor.

Precautions for use

Venous circulation disorders:

This medication is effective when combined with a healthy lifestyle.

Avoid sun exposure, heat, prolonged standing, overweight.

Walking and possibly wearing adapted stockings promote blood circulation.

This medication contains a coloring agent called red cochineal A (E124) which can cause allergic reactions.

Ascorbic acid (vitamin C) can influence the results of biological tests, such as blood glucose, bilirubin, measurement of transaminase activity, lactates and other tests.

Children and Youth

Not applicable.

Other medicines and BICIRKAN, film-coated tablet

Inform your doctor or pharmacist if you are taking, have recently taken or may take any other medicines.

BICIRKAN, film-coated tablet with food and beverages and alcohol

Not applicable.

Pregnancy, breastfeeding and fertility

If you are pregnant or breastfeeding, think you may be pregnant or plan a pregnancy, ask your doctor for advice or pharmacist before taking this medication.

As a precaution, it is preferable to avoid the use of BICIRKAN during pregnancy and it should not be used during breastfeeding.


Not applicable.

Driving and using machines

Not applicable.

BICIRKAN, film-coated tablet contains: cochineal red (E124)

This medicine contains cochineal red (E124) and may cause allergic reactions.

3. HOW TO TAKE BICIRKAN, film-coated tablet?

Always take this medication exactly as prescribed in this leaflet or as directed by your doctor or pharmacist. Check with your doctor or pharmacist if in doubt.


The recommended dose is 2 tablets per day, 1 tablet in the morning and 1 tablet at lunchtime, during meals.

Method and route of administration

This medication is taken orally.

Swallow the tablet as it is with a glass of water.

Usual duration of treatment:

· In venous circulation disorders: If the discomfort and / or fragility of the vessels does not improve after 15 days of treatment, consult your doctor.

· In the hemorrhoidal crisis: treatment should be short-lived. If hemorrhoidal problems persist after a few days of treatment (not more than one week), it is essential to consult your doctor.

Use in children and adolescents

Not applicable .

If you take more BICIRKAN film-coated tablets than you should:

Excessive doses of ascorbic acid (constituent of BICIRKAN) can lead to hemolytic anemia in G6PD-deficient subjects.

Consult your doctor or pharmacist.

If you forget to take BICIRKAN, film-coated tablet:

Do not take a double dose to make up for the single dose you have forgotten to take.

If you stop taking BICIRKAN, film-coated tablet:

Not applicable.

If you have any further questions on the use of this medication, ask your doctor or pharmacist.


Like all medicines, this medicine may cause side effects, although not everybody gets them.

The following side effects may occur:

· Common (1 to 10 patients out of 100)

Diarrhea, sometimes severe, rapidly improving upon cessation of treatment (see section 2 Warnings).

Abdominal pain.

· Uncommon (1 to 10 of 1000 patients)

Nausea, erythema (redness of the skin), pruritus (itching), muscle spasms, pain in the extremities (hands and / or feet), insomnia (difficulty falling asleep), dyspepsia (functional digestive disorder).

· Rare (up to 1 in 1000 patients)

Nervousness, dizziness, coldness of the extremities (coldness of hands and / or feet), venous pain (increased sensitivity of the veins), gastrointestinal disorders, aphthous stomatitis (inflammation of the oral cavity with the presence of vesicles) alanine aminotransferase (increase of a liver biological parameter).

· Not known (frequency can not be determined from available data):

Stomach ache.

Erythema maculopapular (redness of the skin) and urticaria (red plaques in relief associated with itching)

Colitis (inflammation of the colon) reversible upon cessation of treatment.

Declaration of side effects

If you experience any side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly through the national reporting system:

National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Centers for Pharmacovigilance - Website:

By reporting adverse reactions, you are helping to provide more information about the safety of the drug.

5. HOW TO STORE BICIRKAN, film-coated tablet?

Keep this medicine out of the reach and sight of children.

Do not use this medicine after the expiry date which is stated on the package after EXP. The expiry date refers to the last day of that month.

Store at a temperature not exceeding 30 ° C in the outer carton and away from moisture.

Do not throw any medicines into drains or rubbish. Ask your pharmacist to remove any medications you are no longer using. These measures will help protect the environment.


What BICIRKAN contains, film-coated tablet

· The active substances are:

Dry Holly Extract ............................................. .................................................. .... .80.00 mg

Hesperidin methyl chalcone ..................................... .......... ............................................ 200.00 mg

Ascorbic acid (vitamin C) ............................................ ............................................... 400.00 mg

For a film-coated tablet.

· The other components are:

Bare tablet : hypromellose, microcrystalline cellulose, copovidone, crospovidone, talc, anhydrous colloidal silica, magnesium stearate.

Lamination : hypromellose, ethylcellulose, triethylcitrate, titanium dioxide (E171), cochineal red lacquer (E124) (see section 2: BICIRKAN contains : red cochineal (E124))

What is BICIRKAN film-coated tablets and contents of the pack

This drug is in the form of film-coated tablet.

Each box contains 30, 60, 90, 120 or 180 film-coated tablets.

Not all pack sizes may be marketed.

Marketing Authorization Holder


45 place Abel Gance

92100 Boulogne


Marketing Authorization Operator


45 place Abel Gance

92100 Boulogne

la France



45 place Abel Gance

92100 Boulogne


Names of the medicinal product in the Member States of the European Economic Area

Not applicable.

The last date on which this leaflet was revised is:

[to be completed later by the holder]


Detailed information on this medicine is available on the ANSM website (France).

Health Education Council:

Traffic disorders

Avoid sitting or standing too long, slightly elevating your feet, avoiding sun exposure, heat, ensuring a healthy and balanced diet, and regular physical activity (walking, cycling, etc.) , avoid overweight, avoid tight clothing, wearing socks or stockings as well as showering his legs with cold water promote blood circulation.


Drink 1.5 to 2L of water per day, consume high-fiber foods to avoid constipation (fruits, green vegetables, whole grains), avoid fats, coffee, alcohol and spicy foods , exercise regularly to stimulate blood flow, avoid wearing too heavy objects.

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