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    5. NUROFENFEM 400MG TABLETS 12
    NUROFENFEM 400MG TABLETS 12
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    NUROFENFEM 400MG TABLETS 12

    Brand : Reckitt Reckitt
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    Nurofenfem 400 mg 12 tablets is a medicine indicated for adults and children over 30 kg (about 11-12 years), in treatment of acute fever and / or pain such as painful periods, pain head, flu symptoms, dental pain, body aches.

    Medicinal advice
    See delivery conditions

    NUROFENFEM 400MG TABLETS 12

    All medicines containing ibuprofen (nurofen, advil spedifen) on your online pharmacy without a prescription.

    For warnings, precautions for use and contraindications, please see the instructions for use Nurofenfem 400 mg .

    Description NurofenFem 400 mg 12 tablets

    Nurofenfem 400 mg 12 tablets is a medicine indicated for adults and children over 30 kg (about 11-12 years), for the short-term treatment of fever and / or pain such as painful periods, aches headache, flu-like conditions, dental pain, body aches.

    Composition

    • Ibuprofen lysinate: 684 mg per tablet, corresponding to 400 mg of ibuprofen per tablet.
    • Excipients: Core: povidone, sodium carboxymethyl starch (type A), magnesium stearate. Coating: hypromellose, talc, white Opaspray M-1-7111 B (hypromellose, titanium dioxide (E 171)). Black printing ink: shellac, black iron oxide (E172), propylene glycol (E1520).

    using advice

    Dosage : Suitable for adults and children over 30 kg (11-12 years old).

    • Oral use.
    • 1 400 mg tablet per dose, to be renewed if necessary after 6 hours. In all cases, do not exceed 3 tablets of 400 mg per day (i.e. 1,200 mg per day).
    • The duration of treatment is limited to 3 days in case of fever; 5 days in case of pain.
    • The tablets should be swallowed with a full glass of water, and preferably taken with a meal.
    • The 400 mg tablet is reserved for more intense pain or fever or not relieved by a 200 mg ibuprofene tablet.
    • The elderly with an increased risk of side effects, use the lowest possible dose for the shortest time necessary or symptom relief.

    Precautions for use

    Contraindications :

    • Beyond 5 completed months of pregnancy (24 weeks of amenorrhea),
    • History of allergy or asthma triggered by taking this drug or a related drug, including other non-steroidal anti-inflammatory drugs, acetylsalicylic acid (aspirin),
    • History of enlargement to the other constituents of the tablet,
    • History of gastrointestinal bleeding or ulcers related to previous NSAID treatments,
    • Ulcer or bleeding of the stomach or the intestine evolving or recurring,
    • Gastrointestinal hemorrhage, cerebral hemorrhage or other hemorrhage in progress,
    • Severe liver disease,
    • Severe kidney disease,
    • Severe heart disease,
    • Systemic lupus erythematosus

    Precautions :

    • In high doses, greater than 1200 mg / day, this drug has anti-inflammatory properties and can cause sometimes serious drawbacks which are those observed with non-steroidal anti-inflammatory drugs.
    • Medicines like Nurofenfem 400 mg may increase the risk of heart attack (myocardial infarction) or stroke. The risk is all the more important as the doses used are high and the duration of treatment extended.
    • Do not exceed the recommended doses or the duration of treatment.
    • If you have heart problems, if you have had a stroke or if you think you have risk factors for this type of pathology (for example in case of high blood pressure, diabetes, high cholesterol level or if you smoke), please speak with your doctor or pharmacist.
    • If you are a woman, Nurofenfem 400 mg tablet may affect your fertility. Its use is not recommended in women who wish to conceive a child. In women who are having trouble procreating or in whom reproductive tests are in progress, please tell your doctor or pharmacist before taking Nurofenfem.
    • Elderly people have a higher risk of side effects, especially for gastrointestinal bleeding, ulcers and perforations. Kidney, liver and heart functions should be closely monitored. The dosage should be as low as possible for the shortest time necessary to relieve symptoms.
    • This medicine passes into breast milk. As a precautionary measure, avoid using it while breastfeeding.
    • keep out of reach of children.
    • Do not use after the expiration date.
    • Store at a temperature below 25 ° C.

    Read the instructions before use.

    Route of administration: Oral route

    Conditioning

    Box of 12 film-coated tablets

    advice

    Obviously, pain relievers, commonly called pain relievers, appear to be a prime solution for quickly relieving pain. They are classified into 3 categories according to their power.

    • Level 1: aspirin, paracetamol, ibuprofen.
    • Level 2: (supplements or replaces level 1): codeine, dihydrocodeine, dextropropoxyphene and tramadol.
    • Level 3: morphine and opium derivatives.

    To avoid taking too much medication, concoct a small salad flavored with olive oil and it will relieve your pain! Olive oil contains oleocanthal an anti-inflammatory similar to pharmaceutical products, like ibuprofen.

    Good to know : many creams containing painkillers apply with a pleasant massage. You can also massage yourself with essential oils with beneficial properties, such as argan oil, sweet almond, apricot or wheat germ.

    Warnings on pain relievers

    Please note, the Nurofenfem 400 mg medication is not like any other product. Read the package leaflet carefully before ordering. Keep medicines out of the reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Beware of incompatibilities on your current products.

    • Please inform your online pharmacist of the treatments in progress in order to identify any incompatibilities. The order validation form contains a personalized message field provided for this purpose.
    • Click here to find the package leaflet for this Nurofenfem 400 mg medication on the website of the National Agency for the Safety of Medicines and Health Products.

    Pharmacovigilance Report an adverse drug reaction(s)

    Download PDF leaflet

    NOTICE

    ANSM - Last updated: 10/05/2017

    Name of the medicinal product

    NUROFENFEM 400 mg film-coated tablet

    framed

    Read this leaflet carefully before you start taking this medicine. It contains important information for your treatment.

    · This medication can be used in self-medication, ie used without consultation or prescription from a doctor.

    · If symptoms persist, worsen or new symptoms appear, seek advice from your pharmacist or doctor.

    · This leaflet is designed to help you use this medicine. Keep it, you may need to reread it.

    DO NOT LEAVE THIS MEDICINE FOR CHILDREN.

    Review summary

    In this notice :

    1. WHAT IS NUROFENFEM 400 mg film-coated tablet AND WHAT IT IS USED FOR?

    2. BEFORE YOU TAKE NUROFENFEM 400 mg film-coated tablet?

    3. HOW TO TAKE NUROFENFEM 400 mg film-coated tablet?

    4. WHAT ARE POSSIBLE SIDE EFFECTS?

    5. HOW TO STORE NUROFENFEM 400 mg film-coated tablet?

    6. ADDITIONAL INFORMATION

    1. WHAT IS NUROFENFEM 400 mg film-coated tablet AND WHAT IT IS USED FOR?

    Pharmacotherapeutic group

    ANTI-INFLAMMATORY ANTI-RHUMATISMAL NON-STEROID.

    Therapeutic indications

    This medicine contains a non-steroidal anti-inflammatory drug: ibuprofen. It is indicated in adults and children over 30 kg (approximately 11-12 years), in the treatment of short-term fever and / or pain such as headache, flu-like conditions, dental pain, aches, painful periods.

    2. BEFORE YOU TAKE NUROFENFEM 400 mg film-coated tablet?

    List of information needed before taking the medication

    Not applicable.

    Cons-indications

    Do not take NUROFENFEM 400 mg film-coated tablets in the following cases:

    · after 5 months of pregnancy (24 weeks of amenorrhea),

    · a history of allergy or asthma triggered by the use of this drug or a related drug, including other non-steroidal anti-inflammatory drugs, acetylsalicylic acid (aspirin),

    · antecedent allergy to the other constituents of the tablet,

    · history of gastrointestinal bleeding or ulcers associated with previous NSAID treatments,

    · ulceration or bleeding of the stomach or intestine in progress or recurrence,

    · gastrointestinal haemorrhage, cerebral hemorrhage or other ongoing hemorrhage,

    · severe liver disease,

    · severe kidney disease,

    · serious heart disease,

    · systemic lupus erythematosus.

    IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.

    Precautions for use; special warnings

    Take special care with NUROFENFEM 400 mg film-coated tablet:

    In high doses, greater than 1200 mg / day, this drug has anti-inflammatory properties and can cause serious disadvantages that are observed with non-steroidal anti-inflammatory drugs.

    Medications such as NUROFENFEM 400 mg film-coated tablet may increase the risk of heart attack ("myocardial infarction") or stroke. The higher the dose, the longer the treatment time, the greater the risk.

    Do not exceed recommended dosage or treatment time.

    If you have heart problems, have had a stroke, or if you think you have risk factors for this type of illness (eg high blood pressure, diabetes, high cholesterol, or please contact your doctor or pharmacist.

    Special warnings

    If you are a woman, NUROFENFEM 400 mg film-coated tablet can alter your fertility. Its use is not recommended in women who wish to conceive a child. In women with reproductive difficulties or in whom breast function tests are ongoing, please tell your doctor or pharmacist before taking NUROFENFEM 400 mg film-coated tablets.

    Elderly patients have a higher risk of adverse effects, particularly for gastrointestinal haemorrhage, ulcers and perforations. Renal, hepatic and cardiac functions should be closely monitored. The dosage should be as low as possible for the shortest time needed to relieve symptoms.

    BEFORE YOU USE THIS MEDICINE, CONSULT YOUR DOCTOR IN CASE:

    · a history of asthma associated with chronic rhinitis, chronic sinusitis or polyps in the nose. The administration of this specialty may lead to an asthma attack, especially in patients who are allergic to acetylsalicylic acid (aspirin) or to a non-steroidal anti-inflammatory drug ( see section "Never take NUROFENFEM 400 mg film-coated tablets following cases " ),

    · coagulation disorders, and anticoagulant therapy. This medication may cause severe gastrointestinal symptoms,

    · digestive antecedents (hiatal hernia, digestive hemorrhage, old stomach or duodenal ulcer),

    · heart disease, liver or kidney disease,

    · of varicella. This medication is not recommended because of exceptional severe infections of the skin,

    · concomitant treatment with other drugs that increase the risk of peptic ulcer or haemorrhage, eg, oral corticosteroids, antidepressants (SSRIs, ie, Selective Serotonin Recapture Inhibitors), medicines preventing the formation of blood clots such as aspirin or anticoagulants such as warfarin. If you are in any of these conditions, talk to your doctor before taking NUROFENFEM 400 mg film-coated tablets ( see section "Take or use other medicines" ),

    · concomitant therapy with methotrexate at doses greater than 20 mg per week or with pemetrexed ( see section "Take or use other medicinal products" ).

    DURING TREATMENT, IN CASE OF:

    · of vision problems, PREVENT YOUR DOCTOR,

    · gastrointestinal haemorrhage (discharge from the mouth or stool, stool coloration in black), STOP TREATMENT AND IMMEDIATELY CONTACT AN EMERGENCY MEDICAL OR MEDICAL SERVICE,

    · of appearances of cutaneous or mucosal signs that resemble a burn (redness with bubbles or blisters, ulcerations), STOP THE TREATMENT AND CONTACT IMMEDIATELY A DOCTOR OR AN EMERGENCY MEDICAL SERVICE,

    · of allergy-related signs including asthma attack or sudden swelling of the face and neck ( see section "What are the possible side effects?" ), STOP TREATMENT AND CONTACT IMMEDIATELY A DOCTOR OR A MEDICAL SERVICE EMERGENCY.

    This medicine contains a non-steroidal anti-inflammatory drug: ibuprofen.

    You should not take other medicines containing non-steroidal anti-inflammatory drugs (including selective cyclooxygenase 2 inhibitors) and / or acetylsalicylic acid (aspirin) at the same time as this medication. Read carefully the instructions for other medicines you are taking to ensure that there are no nonsteroidal anti-inflammatory drugs and / or acetylsalicylic acid (aspirin).

    Interaction with other medicines

    Taking or using other medicines:

    PLEASE INDICATE YOUR DOCTOR OR YOUR PHARMACIST IF YOU TAKE OR RECENTLY TAKE ANY OTHER MEDICINE, EVEN IF ANY MEDICINE IS OBTAINED WITHOUT ORDER.

    CERTAIN MEDICINAL PRODUCTS MAY NOT BE USED AT THE SAME TIME, WHILE OTHER MEDICINES REQUIRE SPECIFIC CHANGES (DOSE, FOR EXAMPLE).

    Always inform your doctor, dentist or pharmacist if you are taking any of the following medicines in addition to NUROFENFEM 400 mg film-coated tablet:

    · aspirin (acetylsalicylic acid) or other non-steroidal anti-inflammatory drugs

    · corticosteroids

    · oral anticoagulants such as warfarin, injectable heparin, antiplatelet agents or other thrombolytics such as ticlopidine

    · lithium

    · methotrexate

    · angiotensin converting enzyme inhibitors, diuretics, beta-blockers and angiotensin II antagonists

    · some antidepressants (selective serotonin reuptake inhibitors)

    · pemetrexed

    · ciclosporin, tacrolimus.

    Interactions with food and beverages

    Not applicable.

    Interactions with Herbal Medicines or Alternative Therapies

    Not applicable.

    Use during pregnancy and lactation

    Pregnancy and breast feeding

    ASK YOUR DOCTOR OR YOUR PHARMACIST BEFORE TAKING ALL MEDICINAL PRODUCTS.

    Pregnancy

    During the first trimester (12 weeks of gestation is 12 weeks after the 1st day of your last period), your doctor may, if necessary, to prescribe the drug.

    For 2.5 to 5 months of pregnancy (12 to 24 weeks of amenorrhea), this medication will only be used on the advice of your doctor and in brief dosage. Prolonged use of this medication is strongly discouraged.

    After 5 months of pregnancy (beyond 24 weeks of amenorrhea), you should NOT take this medication because its effects on your child can have serious consequences, especially on a cardiopulmonary level and renal, even with a single dose.

    If you are taking this medication when you are more than five months pregnant, please speak to your obstetrician gynecologist for appropriate monitoring.

    feeding

    This drug passes into breast milk. As a precaution, it should be avoided during breastfeeding.

    Sport

    Not applicable.

    Effects on ability to drive or use machines

    Driving and using machines:

    In rare cases, taking this medicine may cause dizziness and blurred vision.

    List of excipients with known effect

    Not applicable.

    3. HOW TO TAKE NUROFENFEM 400 mg film-coated tablet?

    Instructions for proper use

    The occurrence of adverse reactions can be minimized by using the lowest possible dose for the shortest duration necessary to alleviate the symptoms.

    Dosage, Mode and / or route (s) of administration, Frequency of administration and Duration of treatment

    Dosage

    ADULTS TO ADULT AND CHILD WEIGHT MORE THAN 30 KG (11-12 years).

    Painful and / or febrile conditions

    The usual dosage is 1 tablet at 400 mg per dose, to be renewed if necessary after 6 hours. In all cases, do not exceed 3 tablets at 400 mg per day (ie 1200 mg per day).

    The tablet dosed at 400 mg is reserved for pain or fever more intense or not relieved by a tablet dosed with 200 mg of ibuprofen.

    The elderly with an increased risk of adverse effects should use the lowest possible dose for the shortest time necessary to relieve symptoms.

    Administration mode

    Oral use.

    Swallow the tablet without chewing it, with a large glass of water.

    The tablets should be taken preferably during a meal.

    Frequency of Administration

    Regular intakes help prevent fever or pain. They should be spaced at least 6 hours.

    Duration of the treatment

    The duration of use is limited to:

    · 3 days in case of fever,

    · 5 days in case of pain

    If the pain persists more than 5 days or fever more than 3 days, if they worsen or in case of a new disorder, inform your doctor.

    If you feel that the effect of NUROFENFEM 400 mg film-coated tablets is too strong or too weak, talk to your doctor or pharmacist.

    Symptoms and Instructions for Overdose

    If you take more NUROFENFEM 400 mg film-coated tablets than you should:

    In case of accidental overdose, or intoxication, STOP TREATMENT AND QUICKLY CONSULT A DOCTOR.

    Instructions for omission of one or more doses

    If you forget to take NUROFENFEM 400 mg film-coated tablet:

    Do not take a double dose to make up for a missed dose.

    Risk of withdrawal syndrome

    Not applicable.

    4. WHAT ARE POSSIBLE SIDE EFFECTS?

    Description of adverse reactions

    Like all medicines, NUROFENFEM 400 mg film-coated tablets are likely to have side effects, although not everybody gets them.

    Medications such as NUROFENFEM 400 mg film-coated tablet may increase the risk of heart attack (myocardial infarction) or stroke.

    May cause allergic reactions:

    · rash: rash on the skin, itching, edema, aggravation of chronic urticaria,

    · respiratory, asthma crisis,

    · general: sudden swelling of the face and neck (angioedema).

    In rare cases, gastrointestinal hemorrhage may occur ( see section "Take special precautions with NUROFENFEM 400 mg film-coated tablet" ). This is all the more frequent when the dosage used is high.

    Exceptionally, there may be headaches accompanied by nausea, vomiting and neck stiffness.

    Very rarely, bullous manifestations of the skin or mucous membranes (burning sensation accompanied by redness with bubbles, blisters, ulcerations) may occur.

    Exceptionally, severe skin infections have been observed in cases of chicken pox.

    In all these cases, you should stop treatment immediately and notify your doctor.

    During treatment, there may be:

    · digestive disorders: stomach upset, vomiting, nausea, diarrhea, constipation,

    · unusual dizziness, headache, rare visual disturbances, significant decrease in urine, renal insufficiency.

    In all cases, you should tell your doctor.

    · Exceptionally, there have been changes in liver function or blood counts (decreased white blood cells or red blood cells) that may be severe.

    If you notice any side effects not listed in this leaflet, or if any of the side effects gets serious, contact your doctor or pharmacist.

    5. HOW TO STORE NUROFENFEM 400 mg film-coated tablet?

    Keep out of the reach and sight of children.

    Expiration date

    Do not use NUROFENFEM 400 mg film-coated tablets after the expiry date which is stated on the carton.

    The expiry date refers to the last day of the month.

    Storage conditions

    Store at a temperature not exceeding 25 ° C.

    If necessary, warnings against visible signs of deterioration

    Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist what to do with unused medications. These measures will help protect the environment.

    6. ADDITIONAL INFORMATION

    Full list of active substances and excipients

    What contains NUROFENFEM 400 mg film-coated tablet?

    The active substance is:

    Ibuprofen ................................................. .................................................. 400 mg

    In the form of ibuprofen lysinate ........................................... .................................................. ...... 684 mg

    For a film-coated tablet.

    The other components are:

    Core: povidone, sodium carboxymethyl starch (type A), magnesium stearate.

    Pelletizing: hypromellose, talc, OPASPRAY white M-1-7111 B (hypromellose, titanium dioxide (E171)).

    Black printing ink : shellac, black iron oxide (E172), propylene glycol (E1520).

    Pharmaceutical form and content

    What is NUROFENFEM 400 mg film-coated tablets and contents of the pack?

    This drug is in the form of film-coated tablet. Box of 10, 12 or 15.

    Name and address of the marketing authorization holder and the holder of the manufacturing authorization responsible for the release of the lots, if different

    Holder

    RECKITT BENCKISER HEALTHCARE France

    38 RUE VICTOR BASCH

    CS 11018

    91305 MASSY CEDEX

    exploiting

    RECKITT BENCKISER HEALTHCARE France

    38 RUE VICTOR BASCH

    CS 11018

    91305 MASSY CEDEX

    Maker

    RECKITT BENCKISER HEALTHCARE INTERNATIONAL LIMITED

    NOTTINGHAM SITE

    THANE ROAD, NOTTINGHAM

    NOTTINGHAMSHIRE, NG 90 2 DB

    UK

    Names of the medicinal product in the Member States of the European Economic Area

    Not applicable.

    Date of approval of the notice

    The last date on which this leaflet was approved is {date}.

    AMM under exceptional circumstances

    Not applicable.

    Internet Information

    Detailed information on this medicine is available on the Afssaps website (France).

    Information for health professionals only

    Not applicable.

    Other

    ADVICE / HEALTH EDUCATION

    "WHAT TO DO IN THE EVENT OF FEVER":

    The normal temperature of the body is variable from one individual to another and between 36.5 ° C and 37.5 ° C. An increase of more than 0.8 ° C is considered a fever.

    In adults and children over 30 kg (11-12 years of age): if the disorder is too troublesome, you can take a medication containing ibuprofen at the indicated dosage.

    With this medication, the fever should drop rapidly. However:

    · if other signs appear (such as a rash),

    · if the fever persists for more than 3 days or if it worsens,

    · if the headache becomes violent, or in case of vomiting,

    CONSULT YOUR DOCTOR IMMEDIATELY.

    "WHAT TO DO IN CASE OF PAIN":

    · In the absence of improvement after 5 days of treatment,

    · If the pain returns regularly,

    · If accompanied by fever,

    · If she wakes you up at night,

    CONSULT YOUR DOCTOR IMMEDIATELY .

    VIDAL OF THE FAMILY

    NUROFENFEM

    Non-steroidal anti-inflammatory drug

    ibuprofen

    . Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

    PRESENTATIONS (summary)

    NUROFENFEM 400 mg: tablet; box of 12.
    -

    Laboratory Reckitt Benckiser Healthcare France

    COMPOSITION (summary)
    p cp
    Ibuprofen lysinate 684 mg
    Ibuprofen 400 mg

    INDICATIONS (summary)
    This drug is a non- steroidal anti-inflammatory drug ( NSAID ). It combats pain and lowers the fever. Its anti-inflammatory properties manifest in high doses.
    It is used in the treatment of fever and pain (headaches, dental pain, aches, painful periods ...).
    CONTRAINDICATIONS (summary)
    This medication should not be used in the following cases:
    WARNING (Contents)
    Prolonged treatment or overdosage of NSAIDs may result in serious adverse reactions.
    Some situations should lead to further treatment only after medical advice:
    • severe heartburn or black and foul-smelling stools that may indicate irritation or bleeding of the digestive tract;
    • rash without obvious cause;
    • asthma attack ;
    • unusual and intense fatigue, or a sharp and significant decrease in the volume of urine in a person suffering from heart failure , dehydration or diuretic treatment.
    The use of NSAIDs is not recommended in children with varicella: it may increase the risk of infectious, exceptional but potentially serious complications.
    Precautions are necessary in cases of haemorrhagic risk, especially digestive ( Crohn 's disease , ulcerative colitis ).
    NSAIDs have an inhibitory effect on ovulation and are likely to decrease fertility in women. This effect is reversible upon discontinuation of treatment.
    Some doctors consider that anti-inflammatories can decrease the effectiveness of intrauterine devices (IUDs) and expose them to an unwanted pregnancy risk. This risk is highly controversial.
    Conductor: This medication may be responsible, in rare cases, for dizziness or disturbances of vision.
    DRUG INTERACTIONS (summary)
    This medication may interact with other medicines, including: Inform your doctor or pharmacist if you are taking a diuretic , an ACE inhibitor , an angiotensin II inhibitor , a beta-blocker, or a medicine containing ciclosporin.
    PREGNANCY AND BREAST-FEEDING (summary)
    Pregnancy :
    Adverse effects to the unborn child have been demonstrated when NSAIDs are used during the last 4 months of pregnancy; the risk exists even with a single intake and even if the pregnancy is over term. The use of this medication is contraindicated during this period.
    During the first 5 months, the effect of this medication is poorly understood: only your doctor can evaluate the possible risk of its use in your case.

    Breastfeeding:
    This medication passes into breast milk: as a precaution, it is not recommended during breast-feeding.
    DIRECTIONS FOR USE AND DOSAGE (summary)
    In order to limit the occurrence of digestive disorders , this medication can be taken during meals. However, in the case of acute pain, the fasting catch ensures a faster effect.
    The tablets should be swallowed as they are with a large glass of water, without being chewed.

    Usual dosage:

    • Adult and child over 30 kg (about 11 years): 1 tablet at 400 mg per dose, to be renewed if necessary after 6 hours, without exceeding 3 tablets at 400 mg per day.
    In the absence of medical advice, the duration of treatment should be limited to 5 days in case of pain and 3 days in case of fever.
    TIPS (summary)
    This medicinal product may be freely available in certain pharmacies; nevertheless, do not hesitate to ask your pharmacist for advice.
    400 mg ibuprofen is to be used when ibuprofen 200 mg is insufficiently effective. It can nevertheless be used from the outset in the treatment of severe pain.
    Do not exceed the recommended dosage or duration of treatment recommended by your doctor or pharmacist to limit side effects.
    POSSIBLE ADVERSE EFFECTS (summary)
    Nausea, vomiting, gastritis .
    Rarely:

    GLOSSARY (summary)


    NSAIDs
    Abbreviation for non-steroidal anti-inflammatory drug. Family of anti-inflammatory drugs that are not derived from cortisone (steroids), and the best known of which is aspirin.


    allergy
    Skin reaction (itching, pimples, swelling) or general discomfort occurring after contact with a particular substance, use of a medication, or ingestion of food. The main forms of allergy are eczema, urticaria, asthma, angioedema and allergic shock (anaphylactic shock). Food allergy can also result in digestive disorders.


    anemia
    Reduction in the level of hemoglobin in the blood, which usually results in a decrease in the number of red blood cells. Iron is essential for the synthesis of hemoglobin. Iron deficiency during pregnancy, a vegetarian diet, abundant or repeated haemorrhage (menstruation) is a common cause of anemia. Other causes, more rare, are related to vitamin deficiencies of group B.


    antecedent
    Affection healed or always in evolution. The antecedent may be personal or family. The background is the history of a person's health.


    antiplatelet agents
    Medication that prevents the platelets from clumping and therefore the clots from forming. The oldest platelet antiaggregant is aspirin taken in small doses.
    Anti-aggregants should not be confused with anticoagulants with a different mechanism of action.


    anti coagulants
    Medication that prevents blood from coagulating and therefore prevents clots from forming in the blood vessels.
    Anticoagulants are used to treat or prevent phlebitis, pulmonary embolism, certain infarcts. They also prevent the formation of clots in the heart during rhythm disorders such as atrial fibrillation or in the case of an artificial heart valve.
    There are two main types of anticoagulants:
    • oral anticoagulants, which block the action of vitamin K (antivitamin K, or AVK) and whose effectiveness is controlled by a blood test: INR (formerly TP);
    • injectable anticoagulants derived from heparin, the efficacy of which can be controlled by the blood assay of anti-Xa activity, Howell's Time (TH) or Cephalin Kaolin Time (TCK) depending on the products used. A regular dosage of blood platelets is necessary throughout the life of a heparin derivative.


    anti-inflammatory
    Medicine that fights against inflammation. It can be either derived from cortisone (steroidal anti-inflammatory), or not derived from cortisone (nonsteroidal anti-inflammatory or NSAID).


    asthma
    Disease characterized by difficulty breathing, often resulting in wheezing. Asthma, permanent or occurring by crisis, is due to a narrowing and inflammation of the bronchi.


    beta blockers
    Family of drugs used primarily in cardiology. They block the action of adrenaline (and other related hormones) on the heart, vessels and bronchi.


    Crohn
    inflammation of the intestine, which can cause ulcers and narrowing. It often becomes chronic and can be accompanied by persistent diarrhea and malnutrition.


    diuretic
    Medication allowing increased kidney water removal. Most often, this loss of water follows the loss of salts caused by the drug (salidiuretic).
    Diuretics are mainly used in the treatment of high blood pressure, while their mechanism of action in this disease is poorly understood. They are also prescribed in acute or chronic heart failure, edema and other rarer ailments.
    These drugs cause loss of sodium and potassium (except for some of them called "potassium-sparing"). Their prolonged administration therefore requires regular blood potassium control, to avoid heart problems that may result from hypokalemia (lack of potassium in the blood). Lack of sodium is another possible but less frequent consequence of the prolonged use of diuretics; it is also detected by a blood test.


    duodenum
    A part of the intestine into which food from the stomach penetrates.


    skin rash
    Appearance of pimples or plaques on the skin. These lesions can be due to a food, a drug, and translate an allergy or a toxic effect. Many viruses can also cause pimple eruptions: rubella, roseola and measles are the most common.


    gastritis
    Inflammation of the stomach favored by stress, tobacco, alcohol and certain drugs such as aspirin or anti-inflammatory drugs.


    hemorrhage
    Loss of blood from an artery or vein. Hemorrhage can be external, but also internal and go unnoticed.


    angiotensin II inhibitor
    These drugs are sometimes called sartans, for the names of the molecules belonging to this family end with sartan (losartan, candesartan, etc.).
    This family of drugs blocks the action of angiotensin II, a substance that increases blood pressure and tires the heart.
    Angiotensin II inhibitors are used to treat high blood pressure.


    ACE inhibitor
    This family of drugs blocks the action of an enzyme, which converts angiotensin I (naturally inactive substance) to angiotensin II. This last substance increases blood pressure and fatigue the heart.
    ACE inhibitors are used to treat high blood pressure, heart failure or myocardial infarction.


    heart failure
    Inability of the heart to fulfill its function as a pump. The main symptoms of heart failure are fatigue and shortness of breath during an effort.


    Hepatic insufficiency
    Inability of the liver to perform its function, which is essentially the elimination of some waste, but also the synthesis of many biological substances essential to the body: albumin, cholesterol and coagulation factors (vitamin K, etc.).


    renal failure
    Inability of the kidneys to eliminate waste or medicinal substances. Advanced renal insufficiency does not necessarily result in a decrease in the amount of urine excreted. Only a blood test and creatinine dosage may reveal this disease.


    lupus erythematosus
    Skin disease causing redness of the central part of the face. There are two main forms: discoid lupus (only cutaneous) and disseminated lupus (associated with lesions of the deep organs).


    blood count
    The count measures the number of red blood cells (red blood cells), white blood cells (leukocytes) and platelets in the blood. The blood formula specifies the percentage of different white blood cells: neutrophils, eosinophils, basophils, lymphocytes, monocytes.
    Abbreviation: NFS.


    edema
    Accumulation of water or lymph causing localized swelling.


    dosage
    Quantity and distribution of the dose of a drug according to the age, weight and general condition of the patient.


    allergic reaction
    Reaction due to hypersensitivity of the organism to a drug. Allergic reactions can take a wide variety of aspects: urticaria, angioedema, eczema, eruption of pimples resembling measles, etc. Anaphylactic shock is a generalized allergic reaction that causes discomfort due to a sudden drop in blood pressure.


    ulcerative colitis
    Inflammatory disease of the rectum and colon, which evolves by flare-ups. Each flare is accompanied by fever, bloody stools.


    overdose
    Excessive intake of a drug may result in an increase in the intensity of adverse effects or even in the development of specific adverse effects.
    This overdose may result from accidental or voluntary poisoning for suicide, so consult your local Poison Control Center (listed in the appendix to the book). However, in most cases, overdose is the result of an error in the understanding of the prescription, or the search for an increase in efficacy by exceeding the recommended dosage. Finally, untimely self-medication may lead to excessive absorption of the same substance contained in different drugs. Some drugs are particularly prone to this risk because they are (wrongly) considered to be harmless: vitamins A and D, aspirin, etc. Stopping or decreasing drug intake helps to remove the disorders associated with an overdose.


    transaminases
    Enzymes dosed in the blood, which rate rises during some hepatitis. They are included in blood tests as SGOT and SGPT or ASAT and ALAT.


    digestive disorders
    Set of symptoms indicating irritation or malfunction of the digestive tract. One or more disorders may be present: nausea, vomiting, aerophagia, abdominal pain, heartburn, bloating, flatulence, diarrhea or constipation, etc. Antibiotics can promote candidiasis, often responsible for digestive disorders.


    ulcer
    Injury of skin, mucous membranes or cornea.
    • Leg ulcer: chronic wound due to poor circulation of blood.
    • Gastroduodenal ulcer: a localized wound in the mucosa of the stomach or duodenum due to excess acidity and very often to the presence of a bacterium (Helicobacter pylori). The ulcer is favored by stress, alcohol, smoking and certain medications (aspirin, NSAIDs, etc.).


    dizziness
    Symptom that can mean an impression of loss of balance (common sense) or, more strictly, a sense of rotation on oneself or the environment (medical sense).

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