ADVILCAPS 400MG CAPSULES 14 for sale in your medicine approved ars

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For warnings, the precautions and cons-indications, please see the instructions.


Painful conditions and / or fever
The usual dose is 1 capsule 400 mg per dose, repeat if necessary, not to exceed 3 capsules in 400 mg per day (1,200 mg per day).
The capsule is dosed at 400 mg reserved for pain or to a more intense or not relieved by a capsule dosed at 200 mg ibuprofen fever.
The elderly have an increased risk of adverse events, use the lowest dose possible during the shortest necessary duration to control symptoms.
Do not exceed the recommended dose or duration of treatment (3 days for fever, 5 days for pain).
The maximum dose is 3 capsules per day (1200 mg).

Swallow softgel, without chewing, with a full glass of water.
Soft capsules are preferably taken during a meal.

Systematic made it possible to avoid the oscillations of pain or fever.
They should be spaced at least 6 hours.

The duration of use is limited to:
3 days in case of fever,
5 days if pain

If pain persists for more than 5 days or fever more than 3 days or if they get worse or if you experience another disorder, inform your doctor.
If you feel that the effect of ADVILCAPS 400 mg soft capsules is too strong or too weak: Consult your doctor or pharmacist.

Warnings on drugs

Warning, the drug is not a product like any other. Read the package leaflet before ordering. Do not leave medicines out of reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Attention to incompatibilities on products in your.

Tell your pharmacist online treatments underway to identify possible incompatibilities. The checkout form contains a custom message field provided for this purpose.

Click here to find record of the drug at the site of the National Security Agency of Medicines and Health Products.

Pharmacovigilance : Report or a related adverse event (s) (s) (s) the use of a drug

How to manage joint pain (and those of osteoarthritis)?

EULAR recommendations *
1. hydiéno-dietary rules: weight loss, exercise
2. General management: use of analgesic, anti-arthritic slow-acting, and anti-inflammatory
3. Local ownership: joint injections (cortisone, hyaluronic acid)
4. Surgical Management
* European League Against Rheumatism

What advice micronutrition and herbal medicine for joint pain?

1 / Support for pain and inflammation daily

Stage 1: functional gene, morning stiffness, pain unlocking, blocking
Cartimotil Fort PILEJE the dosage of one capsule a day for 3 months
Food complementa combination of 3 excerpts: turmeric extract, boswellia and Laver
Stage 2: permanent pain, chronic, disabling
Fort Cartimotil the dosage of one capsule a day for 3 months and 4 capsules per day during inflammatory processes

+ Application CARTIMOSIL Gel on healthy skin, one to several times a day and massage with light circular movements. Massage Gel combines plant extracts and essential oils to target articular

2 / Treatment of protective cartilage background

Arthrobiane at a dose of 4 tablets per day for 3 months, renewable

Food complementa combination of drugs for osteoarthritis of slow action: glucosamine and chondroitin + Galangal



Non-steroidal anti-inflammatory drug


. Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon


ADVILCAPS 200 mg: soft capsule (light green); box of 16.

ADVILCAPS 400 mg: soft capsule; box of 14.

Pfizer Family Health Laboratory

p caps p caps
Ibuprofen 200 mg 400 mg
sorbitol + +

This drug is a non- steroidal anti-inflammatory drug ( NSAID ). It combats pain and lowers the fever. Its anti-inflammatory properties manifest in high doses.
It is used in the treatment of short duration of fever and pain (headaches, dental pain, muscle aches, painful periods ...).
The 400 mg capsules are also used in the treatment of the migraine crisis in adults, after at least medical advice.
This medication should not be used in the following cases:
WARNING (Contents)
Prolonged treatment or overdosage of NSAIDs may result in serious adverse reactions.
Certain situations must lead to continuation of treatment only after a medical opinion:
  • severe heartburn or black and foul-smelling stools that may indicate irritation or bleeding of the digestive tract;
  • rash without obvious cause;
  • asthma attack ;
  • unusual and intense fatigue, or a sharp and significant decrease in the volume of urine in a person suffering from heart failure , dehydration or diuretic treatment.
Precautions are necessary in the elderly or in case of a history of stomach or duodenal ulcer or haemorrhagic risk, especially digestive ( Crohn 's disease , ulcerative colitis ).
The use of NSAIDs is not recommended in children with varicella: it may increase the risk of infectious, exceptional but potentially serious complications.
NSAIDs have an inhibitory effect on ovulation and are likely to decrease fertility in women. This effect is reversible upon discontinuation of treatment.
Some doctors consider that anti-inflammatories can decrease the effectiveness of intrauterine devices (IUDs) and expose them to an unwanted pregnancy risk. This risk is highly controversial.
Conductor: This medication may be responsible, in rare cases, for dizziness or disturbances of vision.
This medication may interact with other medicines, including: Inform your doctor or pharmacist if you are taking a diuretic , an ACE inhibitor , an angiotensin II inhibitor , a beta-blocker, or a medicine containing ciclosporin.
Pregnancy :
Adverse effects to the unborn child have been demonstrated when NSAIDs are used during the last 4 months of pregnancy; the risk exists even with a single intake and even if the pregnancy is over term. The use of this medication is contraindicated during this period.
During the first 5 months, the effect of this medication is poorly understood: only your doctor can evaluate the possible risk of its use in your case.

Ibuprofen passes in very low amounts in breast milk: its use at the recommended doses is possible during breastfeeding.
In order to limit the occurrence of digestive disorders , this medication can be taken during meals with a large glass of water. However, in the case of acute pain, the fasting catch ensures a faster effect. Catches must be spaced at least 6 hours apart.
Capsules are not suitable for children under 6 years of age. They may clog the airways if the child swallows and the capsule passes into the trachea (false route).

Usual dosage:

Pain and fever:
  • Adult and child over 30 kg (about 11 years): 1 to 2 capsules to 200 mg or 1 capsule to 400 mg, to be renewed if necessary after a minimum period of 6 hours. Do not exceed 6 capsules at 200 mg or 3 capsules at 400 mg per day.
  • Child 20 to 30 kg (approximately 6 to 11 years): 1 capsule to 200 mg, to be renewed if necessary every 6 hours. Do not exceed 3 capsules at 200 mg per day.
In the absence of medical advice, the duration of treatment should be limited to 5 days in case of pain and 3 days in case of fever.
Migraine attack:
  • Adult: 1 capsule to 400 mg, to be taken at the beginning of the crisis. There is no need to take a capsule if the effect is insufficient. On the other hand, if the symptoms reappear, it is possible to take 1 additional capsule within a minimum delay of 8 hours between the 2 catches. Do not exceed 3 days of treatment.
TIPS (summary)
The 400 mg dosage is intended for use when ibuprofen 200 mg is insufficiently effective. It can nevertheless be used from the outset in the treatment of severe pain.
Taking this medication does not dispense with the usual measures to help cede the migraine attack: lie down in a dark room.
Do not exceed the recommended dosage or duration of treatment recommended by your doctor or pharmacist to limit side effects.
This medicinal product may be freely available in certain pharmacies; nevertheless, do not hesitate to ask your pharmacist for advice.
Nausea, vomiting, gastritis .

GLOSSARY (summary)

Abbreviation for non-steroidal anti-inflammatory drug. Family of anti-inflammatory drugs that are not derived from cortisone (steroids), and the best known of which is aspirin.

Skin reaction (itching, pimples, swelling) or general discomfort occurring after contact with a particular substance, use of a medication, or ingestion of food. The main forms of allergy are eczema, urticaria, asthma, angioedema and allergic shock (anaphylactic shock). Food allergy can also result in digestive disorders.

Reduction in the level of hemoglobin in the blood, which usually results in a decrease in the number of red blood cells. Iron is essential for the synthesis of hemoglobin. Iron deficiency during pregnancy, a vegetarian diet, abundant or repeated haemorrhage (menstruation) is a common cause of anemia. Other causes, more rare, are related to vitamin deficiencies of group B.

Affection healed or always in evolution. The antecedent may be personal or family. The background is the history of a person's health.

antiplatelet agents
Medication that prevents the platelets from clumping and therefore the clots from forming. The oldest platelet antiaggregant is aspirin taken in small doses.
Anti-aggregants should not be confused with anticoagulants with a different mechanism of action.

anti coagulants
Medication that prevents blood from coagulating and therefore prevents clots from forming in the blood vessels.
Anticoagulants are used to treat or prevent phlebitis, pulmonary embolism, certain infarcts. They also prevent the formation of clots in the heart during rhythm disorders such as atrial fibrillation or in the case of an artificial heart valve.
There are two main types of anticoagulants:
  • oral anticoagulants, which block the action of vitamin K (antivitamin K, or AVK) and whose effectiveness is controlled by a blood test: INR (formerly TP);
  • injectable anticoagulants derived from heparin, the efficacy of which can be controlled by the blood assay of anti-Xa activity, Howell's Time (TH) or Cephalin Kaolin Time (TCK) depending on the products used. A regular dosage of blood platelets is necessary throughout the life of a heparin derivative.

Medicine that fights against inflammation. It can be either derived from cortisone (steroidal anti-inflammatory), or not derived from cortisone (nonsteroidal anti-inflammatory or NSAID).

Disease characterized by difficulty breathing, often resulting in wheezing. Asthma, permanent or occurring by crisis, is due to a narrowing and inflammation of the bronchi.

beta blockers
Family of drugs used primarily in cardiology. They block the action of adrenaline (and other related hormones) on the heart, vessels and bronchi.

inflammation of the intestine, which can cause ulcers and narrowing. It often becomes chronic and can be accompanied by persistent diarrhea and malnutrition.

Medication allowing increased kidney water removal. Most often, this loss of water follows the loss of salts caused by the drug (salidiuretic).
Diuretics are mainly used in the treatment of high blood pressure, while their mechanism of action in this disease is poorly understood. They are also prescribed in acute or chronic heart failure, edema and other rarer ailments.
These drugs cause loss of sodium and potassium (except for some of them called "potassium-sparing"). Their prolonged administration therefore requires regular blood potassium control, to avoid heart problems that may result from hypokalemia (lack of potassium in the blood). Lack of sodium is another possible but less frequent consequence of the prolonged use of diuretics; it is also detected by a blood test.

A part of the intestine into which food from the stomach penetrates.

skin rash
Appearance of pimples or plaques on the skin. These lesions can be due to a food, a drug, and translate an allergy or a toxic effect. Many viruses can also cause pimple eruptions: rubella, roseola and measles are the most common.

Inflammation of the stomach favored by stress, tobacco, alcohol and certain drugs such as aspirin or anti-inflammatory drugs.

Loss of blood from an artery or vein. Hemorrhage can be external, but also internal and go unnoticed.

angiotensin II inhibitor
These drugs are sometimes called sartans, for the names of the molecules belonging to this family end with sartan (losartan, candesartan, etc.).
This family of drugs blocks the action of angiotensin II, a substance that increases blood pressure and tires the heart.
Angiotensin II inhibitors are used to treat high blood pressure.

ACE inhibitor
This family of drugs blocks the action of an enzyme, which converts angiotensin I (naturally inactive substance) to angiotensin II. This last substance increases blood pressure and fatigue the heart.
ACE inhibitors are used to treat high blood pressure, heart failure or myocardial infarction.

heart failure
Inability of the heart to fulfill its function as a pump. The main symptoms of heart failure are fatigue and shortness of breath during an effort.

Hepatic insufficiency
Inability of the liver to perform its function, which is essentially the elimination of some waste, but also the synthesis of many biological substances essential to the body: albumin, cholesterol and coagulation factors (vitamin K, etc.).

renal failure
Inability of the kidneys to eliminate waste or medicinal substances. Advanced renal insufficiency does not necessarily result in a decrease in the amount of urine excreted. Only a blood test and creatinine dosage may reveal this disease.

lupus erythematosus
Skin disease causing redness of the central part of the face. There are two main forms: discoid lupus (only cutaneous) and disseminated lupus (associated with lesions of the deep organs).

Special headache usually affecting the right or left half of the head, often associated with a fear of light and noise.

blood count
The count measures the number of red blood cells (red blood cells), white blood cells (leukocytes) and platelets in the blood. The blood formula specifies the percentage of different white blood cells: neutrophils, eosinophils, basophils, lymphocytes, monocytes.
Abbreviation: NFS.

Accumulation of water or lymph causing localized swelling.

Quantity and distribution of the dose of a drug according to the age, weight and general condition of the patient.

allergic reaction
Reaction due to hypersensitivity of the organism to a drug. Allergic reactions can take a wide variety of aspects: urticaria, angioedema, eczema, eruption of pimples resembling measles, etc. Anaphylactic shock is a generalized allergic reaction that causes discomfort due to a sudden drop in blood pressure.

ulcerative colitis
Inflammatory disease of the rectum and colon, which evolves by flare-ups. Each flare is accompanied by fever, bloody stools.

Excessive intake of a drug may result in an increase in the intensity of adverse effects or even in the development of specific adverse effects.
This overdose may result from accidental or voluntary poisoning for suicide, so consult your local Poison Control Center (listed in the appendix to the book). However, in most cases, overdose is the result of an error in the understanding of the prescription, or the search for an increase in efficacy by exceeding the recommended dosage. Finally, untimely self-medication may lead to excessive absorption of the same substance contained in different drugs. Some drugs are particularly prone to this risk because they are (wrongly) considered to be harmless: vitamins A and D, aspirin, etc. Stopping or decreasing drug intake helps to remove the disorders associated with an overdose.

crisis management
As opposed to long-term treatment, short-term and episodic treatment in the context of seizure or outbreak diseases.

Enzymes dosed in the blood, which rate rises during some hepatitis. They are included in blood tests as SGOT and SGPT or ASAT and ALAT.

digestive disorders
Set of symptoms indicating irritation or malfunction of the digestive tract. One or more disorders may be present: nausea, vomiting, aerophagia, abdominal pain, heartburn, bloating, flatulence, diarrhea or constipation, etc. Antibiotics can promote candidiasis, often responsible for digestive disorders.

Injury of skin, mucous membranes or cornea.
  • Leg ulcer: chronic wound due to poor circulation of blood.
  • Gastroduodenal ulcer: a localized wound in the mucosa of the stomach or duodenum due to excess acidity and very often to the presence of a bacterium (Helicobacter pylori). The ulcer is favored by stress, alcohol, smoking and certain medications (aspirin, NSAIDs, etc.).

Symptom that can mean an impression of loss of balance (common sense) or, more strictly, a sense of rotation on oneself or the environment (medical sense).

Cliquez ici pour retrouver la notice de ce médicament sur le site de l'Agence Nationale de Sécurité du Médicament et des produits de santé.

Pharmacovigilance : Déclarer un ou des effet(s) indésirable(s) lié(s) à l'utilisation d'un médicament


ANSM - Last updated: 13/08/2015

Name of the medicinal product

ADVILCAPS 400 mg soft capsule



Read this leaflet carefully before you start using this medicine. It contains important information for your treatment.

· This medication can be used in self-medication, ie used without consultation or prescription from a doctor.

· If symptoms persist, worsen or new symptoms appear, seek advice from your pharmacist or doctor.

· This leaflet is designed to help you use this medicine. Keep it, you may need to reread it.


Review summary

In this notice :

1. WHAT IS ADVILCAPS 400 mg, soft capsule AND WHAT IT IS USED FOR?

2. BEFORE YOU TAKE ADVILCAPS 400 mg, soft capsule?

3. HOW TO TAKE ADVILCAPS 400 mg, soft capsule?


5. HOW TO STORE ADVILCAPS 400 mg, soft capsule?


1. WHAT IS ADVILCAPS 400 mg, soft capsule AND WHAT IT IS USED FOR?

Pharmacotherapeutic group


Therapeutic indications

This medicine contains a non-steroidal anti-inflammatory drug: ibuprofen.

It is indicated in adults and children from 30 kg (approximately 11-12 years), in the short-term treatment of fever and / or pain such as headache, flu-like conditions, dental pain , aches and pains.

It is indicated in adults , after at least medical advice , in the treatment of mild to moderate migraine attack, with or without aura.

2. BEFORE YOU TAKE ADVILCAPS 400 mg, soft capsule?

List of information needed before taking the medication

If your doctor has told you about an intolerance to some sugars, contact your doctor before taking this medicine.


Do not take ADVILCAPS 400 mg soft capsules in the following cases:

· after 5 months of pregnancy (24 weeks of amenorrhea),

· a history of allergy or asthma triggered by the use of this drug or a related drug, including other non-steroidal anti-inflammatory drugs, acetylsalicylic acid (aspirin),

· antecedent allergy to the other constituents of the soft capsule,

· history of gastrointestinal bleeding or ulcers associated with previous NSAID treatments,

· ulceration or bleeding of the stomach or intestine in progress or recurrence,

· gastrointestinal haemorrhage, cerebral hemorrhage or other ongoing hemorrhage,

· severe liver disease,

· severe kidney disease,

· serious heart disease,

· systemic lupus erythematosus.


Precautions for use; special warnings

Take special care with ADVILCAPS 400 mg soft capsule:

In high doses, greater than 1200 mg / day, this drug has anti-inflammatory properties and can cause serious disadvantages that are observed with non-steroidal anti-inflammatory drugs.

Drugs such as ADVILCAPS 400 mg, soft capsule may increase the risk of heart attack ("myocardial infarction") or stroke. The risk is higher the higher the doses prolonged treatment.

Do not exceed recommended dosage or treatment time.

If you have heart problems, have had a stroke, or if you think you have risk factors for this type of illness (eg high blood pressure, diabetes, high cholesterol, or please contact your doctor or pharmacist.

Special warnings

If you are a woman, ADVILCAPS 400 mg, soft capsule can impair your fertility. Its use is not recommended in women who wish to conceive a child. In women with reproductive difficulties or in whom breast function tests are ongoing, please talk to your doctor or pharmacist before taking ADVILCAPS 400 mg soft capsule.

Elderly patients have a higher risk of adverse effects, particularly for gastrointestinal haemorrhage, ulcers and perforations. Renal, hepatic and cardiac functions should be closely monitored. The dosage should be as low as possible for the shortest time needed to relieve symptoms.

The use of this medication is not recommended in patients with fructose intolerance (rare hereditary disease).


· a history of asthma associated with chronic rhinitis, chronic sinusitis or polyps in the nose. Administration of this specialty may lead to an asthma attack, especially in some people who are allergic to acetylsalicylic acid (aspirin) or to a non-steroidal anti-inflammatory drug ( see section "Do not take ADVILCAPS 400 mg, soft capsule following cases " ),

· coagulation disorders, and anticoagulant therapy. This medication may cause severe gastrointestinal symptoms,

· digestive antecedents (hiatal hernia, digestive hemorrhage, old stomach or duodenal ulcer),

· heart disease, liver or kidney disease,

· of varicella. This medication is not recommended because of exceptional severe infections of the skin,

· concomitant treatment with other drugs that increase the risk of peptic ulcer or haemorrhage, eg, oral corticosteroids, antidepressants (SSRIs, ie, Selective Serotonin Recapture Inhibitors), medicines preventing the formation of blood clots such as aspirin or anticoagulants such as warfarin. If you are in any of these conditions, talk to your doctor before taking ADVILCAPS 400 mg, soft capsule ( see section "Take or use other medicines" ),

· concomitant therapy with methotrexate at doses greater than 20 mg per week or with pemetrexed ( see section "Take or use other medicinal products" ).


· of vision problems, PREVENT YOUR DOCTOR,

· gastrointestinal haemorrhage (discharge from the mouth or stool, stool coloration in black), STOP TREATMENT AND IMMEDIATELY CONTACT AN EMERGENCY MEDICAL OR MEDICAL SERVICE,

· of appearances of cutaneous or mucosal signs that resemble a burn (redness with bubbles or blisters, ulcerations), STOP THE TREATMENT AND CONTACT IMMEDIATELY A DOCTOR OR AN EMERGENCY MEDICAL SERVICE,

· of allergy-related signs including asthma attack or sudden swelling of the face and neck ( see section "What are the possible side effects?" ), STOP TREATMENT AND CONTACT IMMEDIATELY A DOCTOR OR A MEDICAL SERVICE EMERGENCY.

This medicine contains a non-steroidal anti-inflammatory drug: ibuprofen .

You should not take other medicines containing non-steroidal anti-inflammatory drugs (including selective cyclooxygenase 2 inhibitors) and / or acetylsalicylic acid (aspirin) at the same time as this medication. Read carefully the instructions for other medicines you are taking to ensure that there are no nonsteroidal anti-inflammatory drugs and / or acetylsalicylic acid (aspirin).

Interaction with other medicines

Taking or using other medicines:



Always inform your doctor, dentist or pharmacist if you are taking any of the following medications in addition to ADVILCAPS 400 mg soft capsule:

· aspirin (acetylsalicylic acid) or other non-steroidal anti-inflammatory drugs

· corticosteroids

· oral anticoagulants such as warfarin, injectable heparin, antiplatelet agents or other thrombolytics such as ticlopidine

· lithium

· methotrexate

· angiotensin converting enzyme inhibitors, diuretics, beta-blockers and angiotensin II antagonists

· some antidepressants (selective serotonin reuptake inhibitors)

· pemetrexed

· ciclosporin, tacrolimus.

Interactions with food and beverages

Not applicable.

Interactions with Herbal Medicines or Alternative Therapies

Not applicable.

Use during pregnancy and lactation

Pregnancy and breast feeding



During the first trimester (12 weeks of gestation is 12 weeks after the 1st day of your last period), your doctor may, if necessary, to prescribe the drug.

For 2.5 to 5 months of pregnancy (12 to 24 weeks of amenorrhea), this medication will only be used on the advice of your doctor and in brief dosage. Prolonged use of this medication is strongly discouraged.

After 5 months of pregnancy (beyond 24 weeks of amenorrhea), you should NOT take this medication because its effects on your child can have serious consequences, especially on a cardiopulmonary level and renal, even with a single dose.

If you are taking this medication when you are more than five months pregnant, please speak to your obstetrician gynecologist for appropriate monitoring.


This drug passes into breast milk. As a precaution, it should be avoided during breastfeeding.


Not applicable.

Effects on ability to drive or use machines

Driving and using machines:

In rare cases, taking this medicine may cause dizziness and blurred vision.

List of excipients with known effect

Important information about some of the ingredients of ADVILCAPS 400 mg soft capsule:

This medicine contains sorbitol (E420) and maltitol (E965).

3. HOW TO TAKE ADVILCAPS 400 mg, soft capsule?

Instructions for proper use

The occurrence of adverse reactions can be minimized by using the lowest possible dose for the shortest duration necessary to alleviate the symptoms.

Dosage, Mode and / or route (s) of administration, Frequency of administration and Duration of treatment


Painful and / or febrile conditions


The usual dosage is 1 capsule to 400 mg per dose, to be renewed if necessary every 6 to 8 hours, not to exceed 3 capsules to 400 mg per day (ie 1200 mg per day).

The capsule dosed at 400 mg is reserved for pain or fever more intense or not relieved by a capsule dosed with 200 mg of ibuprofen.

The elderly with an increased risk of adverse effects should use the lowest possible dose for the shortest time necessary to relieve symptoms.

Do not exceed the recommended doses or the duration of treatment (3 days in case of fever, 5 days in case of pain).

The maximum dosage is 3 capsules per day (1200 mg).

In the event of a migraine attack


1 capsule to 400 mg as soon as possible from the beginning of the crisis.

If a patient is not relieved after the first dose, a second dose should not be taken during the same course. However the crisis can be treated with another treatment that is not a nonsteroidal anti-inflammatory or aspirin.

If the pain reappears a second dose can be taken as long as it meets an 8 hour interval between the 2 doses.

If in doubt, ask your doctor or pharmacist for advice.

Administration mode

Oral use.

Swallow the capsule, without chewing it, with a large glass of water.

The capsules should be taken preferably during a meal.

Frequency of Administration

Systematic catches help to avoid oscillations of pain or fever.

They should be spaced at least 6 hours.

Duration of the treatment

The duration of use is limited to:

· 3 days in case of fever,

· 3 days in case of migraine,

· 5 days in case of pain

If the pain persists more than 5 days or fever more than 3 days, if they worsen or in case of a new disorder, inform your doctor.

In case of a migraine attack the duration of treatment should not exceed 3 days.

If symptoms persist or if new symptoms appear, seek the advice of your pharmacist or doctor.

If you feel that the effect of ADVILCAPS 400 mg, soft capsule is too strong or too weak: talk to your doctor or pharmacist.

Symptoms and Instructions for Overdose

If you take more ADVILCAPS 400 mg, soft capsule than you should:

In case of accidental overdose or intoxication, STOP TREATMENT AND IMMEDIATELY CONSULT YOUR DOCTOR.

Instructions for omission of one or more doses

If you forget to take ADVILCAPS 400 mg, soft capsule:

Do not take a double dose to make up for the single dose that you have forgotten to take.

Risk of withdrawal syndrome

Not applicable.


Description of adverse reactions

Like all medicines, ADVILCAPS 400 mg, soft capsule is likely to have side effects, although not everyone is subject to it.

Medications such as ADVILCAPS 400 mg, soft capsule may increase the risk of heart attack (myocardial infarction) or stroke.

May cause allergic reactions :

· rash: rash on the skin, itching, edema, aggravation of chronic urticaria,

· respiratory, asthma crisis,

· general: abrupt swelling of the face and neck with respiratory gene (angioedema).

In rare cases, gastrointestinal haemorrhage may occur ( see section "Take special precautions with ADVILCAPS 400 mg soft capsule" ). This is all the more frequent when the dosage used is high.

Exceptionally, there may be headaches accompanied by nausea, vomiting and neck stiffness.

Exceptionally, severe skin infections have been observed in cases of chicken pox.

Very rarely, bullous manifestations of the skin or mucous membranes (burning sensation accompanied by redness with bubbles, blisters, ulcerations) may occur.

In all these cases, you should stop treatment immediately and notify your doctor.

During treatment, there may be:

· digestive disorders: stomach upset, vomiting, nausea, diarrhea, constipation,

· unusual dizziness, headache, rare visual disturbances, significant decrease in urine, renal insufficiency.

In all cases, you should tell your doctor.

· Exceptionally, there have been changes in liver function or blood counts (decreased white blood cells or red blood cells) that may be severe.

Declaration of side effects

If you experience any side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Centers of Pharmacovigilance. www.ansm.sante.fr . By reporting adverse reactions, you are helping to provide more information about the safety of the drug.

5. HOW TO STORE ADVILCAPS 400 mg, soft capsule?

Keep out of the reach and sight of children.

Expiration date

Do not use ADVILCAPS 400 mg, soft capsule after the expiry date stated on the carton.

Storage conditions

Store at a temperature not exceeding 25 ° C.

If necessary, warnings against visible signs of deterioration

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist what to do with unused medications. These measures will help protect the environment.


Full list of active substances and excipients

What does ADVILCAPS 400 mg contain, soft capsule?

The active substance is:

Ibuprofen ................................................. .................................................. ................................ 400.00 mg

For a soft capsule.

The other components are:

Macrogol 600, 50% solution of potassium hydroxide.

Capsule envelope : partially dehydrated liquid sorbitol *, gelatin, purified water.

Ink for printing : OPACODE NSP-78-17827 (alcohol SDA 35A (ethanol and ethyl acetate), propylene glycol, black iron oxide (E172), polyvinyl acetate phthalate, purified water, isopropyl alcohol, macrogol 400, aluminum to 28%).

Partially dehydrated liquid sorbitol contains sorbitol, maltitol, 1,4-sorbitan, sorbitans and purified water.

Pharmaceutical form and content

What is ADVILCAPS 400 mg, soft capsule and contents of the pack?

This medication is in the form of a soft capsule.

Box of 8, 9, 10, 12 or 14.

Not all pack sizes may be marketed.

Name and address of the marketing authorization holder and the holder of the manufacturing authorization responsible for the release of the lots, if different



23-25, avenue du Docteur


75014 PARIS



23-25 ​​rue du Docteur Lannelongue

75014 PARIS




04011 APRILIA (LT)


Names of the medicinal product in the Member States of the European Economic Area

Not applicable.

Date of approval of the notice

The last date on which this leaflet was approved is {date}.

AMM under exceptional circumstances

Not applicable.

Internet Information

Detailed information on this medicine is available on the Afssaps website (France).

Information for health professionals only

Not applicable.




The normal temperature of the body is variable from one individual to another and between 36.5 ° C and 37.5 ° C. An increase of more than 0.8 ° C is considered a fever.

In adults and children over 30 kg (approximately 11-12 years of age) : If the condition is too troublesome, you can take a medicine containing ibuprofen at the indicated dosage.

With this medication, the fever should drop rapidly. Nevertheless :

· if other signs appear (such as a rash),

· if the fever persists for more than 3 days or if it worsens,

· if the headache becomes violent, or in case of vomiting,



· In the absence of improvement after 5 days of treatment,

· If the pain returns regularly,

· If accompanied by fever,

· If she wakes you up at night,



· Headache for a few hours to 3 days (without pain between seizures).

· At least 5 crises in your life

· Headache having at least 2 of the following characteristics:

o Located on one side of the head;

o Pulsatile (taps in the head);

o Intensity of moderate or severe pain;

o Pain aggravated by physical activities (climbing or descending stairs for example).

· The headache is accompanied by at least one of the following signs:

o nausea and / or vomiting;

o discomfort to light (photophobia) and / or noise (phonophobia).

A positive answer to 3 or 4 of these questions means that you are probably or certainly migraineous.


· Are you relieved significantly 2 hours after taking?

· Is this drug well tolerated?

· Do you use a single medication intake?

· If you are taking this medication, you may be able to resume your usual activities

· 2 hours near the plug?

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