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ADVILCAPS 200MG 16 CAPSULES
Over-the-counter medication

ADVILCAPS 200MG 16 CAPSULES

Brand : GlaxoSmithKline GlaxoSmithKline
€3.41 EXCL. VAT €3.75 INCL. VAT
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Reference : 3400938162974
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ADVILCAPS 200 mg soft capsules is indicated for the acute treatment of fever and / or pain such as headaches, flu symptoms, toothache, menstrual pain and aches. ADVILCAPS is 200 mg for adults and children from 6 years.

ADVILCAPS 200 MG 16 CAPSULES

For warnings, precautions for use and contraindications, please consult the instructions for use.  

Description Advilcaps 200 mg

ADVILCAPS 200 mg soft capsule is indicated for the short-term treatment of fever and / or pain such as headache, flu-like conditions, dental pain, muscle aches and menstruation. ADVILCAPS 200 mg is reserved for adults and children from 6 years old.

Ibuprofen blocks the production and release of chemicals in the body that cause pain and inflammation. It can also reduce fever by adjusting the body's thermostat located in the brain.
Pain and fever are useful because they act as a warning signal. However, you must be very vigilant and consult a doctor if the pain persists or if the fever increases.

using advice

Dosage and route of administration

  • For children from 6 to 11 years old (approximately 20 to 30 kg), 1 ADVILCAPS 200 mg capsule, to be renewed if necessary after 6 hours. In any case, do not exceed 3 capsules per day.
  • For adults and children from 11-12 years old (around 30 kg), 1 to 2 capsules ADVILCAPS 200 mg to be renewed if necessary after 6 hours.

In any case, do not exceed 6 capsules per day.

Oral use.

Composition Advilcaps 200 mg

IBUPROFENE 200 MG. EXCIPIENTS: MACROGOL 600; POTASSIUM HYDROXIDE (50% SOLUTION); SORBITOL LIQUID; GELATINE; PURIFIED WATER ; PATENT BLUE V (E 131); QUINOLEINE YELLOW (E 104); WHITE OPACODE NSP-78-18022; ALCOHOL SDA 35A; PROPYLENE GLYCOL ; TITANIUM DIOXIDE (E 171); POLYVINYL ACETOPHTHALATE; PURIFIED WATER ; ISOPROPYLIC ALCOHOL ; MACROGOL 400; 28% AMMONIUM HYDROXIDE; QSP 1 SOFT CAPSULE.

Notable excipients
SORBITOL

Precautions for use

Contraindication and warning

  • Pregnancy of more than 5 months;
  • history of allergy or asthma triggered by taking ibuprofen or substances of close activity such as other non-steroidal anti-inflammatory drugs, aspirin;
  • hepatocellular insufficiency;
  • severe renal failure;
  • severe heart failure;
  • systemic lupus erythematosus;
  • history of bleeding or digestive perforation;
  • active peptic ulcer;
  • Allergy to Fructose.

ADVILCAPS 200 mg is a drug which requires special attention in subjects with a history of hypertension and / or heart failure, cases of fluid retention, hypertension and edema having been reported in association with treatment with NSAIDs. ADVILCAPS 200 mg is not recommended for subjects with gastrointestinal problems (ulcer, gastrointestinal perforation).

Conditioning

Blister 16 capsules.

Warnings on pain relievers

Attention, the drug Advilcaps 200 Mg is not a product like the others. Read the package leaflet carefully before ordering. Keep medicines out of the reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Beware of incompatibilities on your current products.

  • Please inform your online pharmacist of the treatments in progress in order to identify any incompatibilities. The order validation form contains a personalized message field provided for this purpose.
  • Click here to find the leaflet for this medication on the website of the National Agency for the Safety of Medicines and Health Products.

Pharmacovigilance Report an adverse drug reaction(s)

Download PDF leaflet

NOTICE

ANSM - Updated on: 16/07/2015

Name of the medicinal product

ADVILCAPS 200 mg soft capsule

Ibuprofen

framed

Read this leaflet carefully before you start using this medicine. It contains important information for your treatment.

· This medication can be used in self-medication, ie used without consultation or prescription from a doctor.

· If symptoms persist, worsen or new symptoms appear, seek advice from your pharmacist or doctor.

· This leaflet is designed to help you use this medicine. Keep it, you may need to reread it.

DO NOT LEAVE THIS MEDICINE FOR CHILDREN.

Review summary

In this notice :

1. WHAT IS ADVILCAPS 200 mg, soft capsule AND WHAT USE IS IT USED FOR?

2. BEFORE YOU TAKE ADVILCAPS 200 mg, soft capsule?

3. HOW TO TAKE ADVILCAPS 200 mg, soft capsule?

4. WHAT ARE POSSIBLE SIDE EFFECTS?

5. HOW TO STORE ADVILCAPS 200 mg, soft capsule?

6. ADDITIONAL INFORMATION

1. WHAT IS ADVILCAPS 200 mg, soft capsule AND WHAT USE IS IT USED FOR?

Pharmacotherapeutic group

ANALGESIC AND ANTIPYRETIC.

Therapeutic indications

This medicine contains a non-steroidal anti-inflammatory drug: ibuprofen.

It is indicated in adults and children over 20 kg (about 6 years), in the treatment of short-term fever and / or pain such as:

· headache,

· influenza States,

· dental pains,

· aches,

· painful periods.

2. BEFORE YOU TAKE ADVILCAPS 200 mg, soft capsule?

List of information needed before taking the medication

If your doctor has told you about an intolerance to some sugars, contact your doctor before taking this medicine.

Cons-indications

Do not take ADVILCAPS 200 mg, soft capsule in the following cases:

· after 5 months of pregnancy (24 weeks of amenorrhea),

· a history of allergy or asthma triggered by the use of this drug or a related drug, including other non-steroidal anti-inflammatory drugs, acetylsalicylic acid (aspirin),

· antecedent allergy to the other constituents of the capsule,

· history of gastrointestinal bleeding or ulcers associated with previous NSAID treatments,

· ulceration or bleeding of the stomach or intestine in progress or recurrence,

· gastrointestinal haemorrhage, cerebral hemorrhage or other ongoing hemorrhage,

· severe liver disease,

· severe kidney disease,

· serious heart disease,

· systemic lupus erythematosus,

· child under 6 years old because it can swallow and choke.

IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.

Precautions for use; special warnings

Take special care with ADVILCAPS 200 mg soft capsule:

In high doses, greater than 1200 mg / day, this drug has anti-inflammatory properties and can cause serious disadvantages that are observed with non-steroidal anti-inflammatory drugs.

Medications such as ADVILCAPS 200 mg, soft capsule may increase the risk of heart attack ("myocardial infarction") or stroke. Risk is higher the higher the doses used and the duration of prolonged treatment.

Do not exceed recommended dosage or treatment time.

If you have heart problems, have had a stroke, or if you think you have risk factors for this type of illness (eg high blood pressure, diabetes, high cholesterol, or please contact your doctor or pharmacist.

Special warnings

If you are a woman, ADVILCAPS 200 mg soft capsule can alter your fertility. Its use is not recommended in women who wish to conceive a child. In women with reproductive difficulties or in whom reproductive function tests are ongoing, please tell your doctor or pharmacist before taking ADVILCAPS 200 mg soft capsule.

Elderly patients have a higher risk of adverse effects, particularly for gastrointestinal haemorrhage, ulcers and perforations. Renal, hepatic and cardiac functions should be closely monitored. The dosage should be as low as possible for the shortest time needed to relieve symptoms.

The use of this medication is not recommended in patients with fructose intolerance (rare hereditary disease).

BEFORE YOU USE THIS MEDICINE, CONSULT YOUR DOCTOR IN CASE:

· a history of asthma associated with chronic rhinitis, chronic sinusitis or polyps in the nose. Administration of this medicinal product may lead to an asthma attack, especially in patients who are allergic to acetylsalicylic acid (aspirin) or to a non-steroidal anti-inflammatory drug ( see section "Do not take ADVILCAPS 200 mg, soft capsule following cases " ),

· coagulation disorders, and anticoagulant therapy. This medication may cause severe gastrointestinal symptoms,

· digestive antecedents (hiatal hernia, digestive hemorrhage, old stomach or duodenal ulcer),

· heart disease, liver or kidney disease,

· of varicella. This medication is not recommended because of exceptional severe infections of the skin,

· concomitant treatment with other drugs that increase the risk of peptic ulcer or haemorrhage, eg, oral corticosteroids, antidepressants (SSRIs, ie, Selective Serotonin Recapture Inhibitors), medicines preventing the formation of blood clots such as aspirin or anticoagulants such as warfarin. If you are in any of these conditions, consult your doctor before taking ADVILCAPS 200 mg soft capsule ( see section "Take or use other medicines" ),

· concomitant therapy with methotrexate at doses greater than 20 mg per week or with pemetrexed ( see section "Take or use other medicinal products" ).

DURING TREATMENT, IN CASE OF:

· of vision problems, PREVENT YOUR DOCTOR,

· gastrointestinal haemorrhage (discharge from the mouth or stool, stool coloration in black), STOP TREATMENT AND IMMEDIATELY CONTACT AN EMERGENCY MEDICAL OR MEDICAL SERVICE,

· of appearances of cutaneous or mucosal signs that resemble a burn (redness with bubbles or blisters, ulcerations), STOP THE TREATMENT AND CONTACT IMMEDIATELY A DOCTOR OR AN EMERGENCY MEDICAL SERVICE,

· of allergy-related signs including asthma attack or sudden swelling of the face and neck ( see section "What are the possible side effects?" ), STOP TREATMENT AND CONTACT IMMEDIATELY A DOCTOR OR A MEDICAL SERVICE EMERGENCY.

This medicine contains a non-steroidal anti-inflammatory drug: ibuprofen.

You should not take other medicines containing non-steroidal anti-inflammatory drugs (including selective cyclooxygenase 2 inhibitors) and / or acetylsalicylic acid (aspirin) at the same time as this medication. Read carefully the instructions for other medicines you are taking to ensure that there are no nonsteroidal anti-inflammatory drugs and / or acetylsalicylic acid (aspirin).

Interaction with other medicines

Taking or using other medicines:

PLEASE INDICATE YOUR DOCTOR OR YOUR PHARMACIST IF YOU TAKE OR RECENTLY TAKE ANY OTHER MEDICINE, EVEN IF ANY MEDICINE IS OBTAINED WITHOUT ORDER.

CERTAIN MEDICINAL PRODUCTS MAY NOT BE USED AT THE SAME TIME, WHILE OTHER MEDICINES REQUIRE SPECIFIC CHANGES (DOSE, FOR EXAMPLE).

Always inform your doctor, dentist or pharmacist if you are taking any of the following medications in addition to ADVILCAPS 200 mg soft capsule:

· aspirin (acetylsalicylic acid) or other non-steroidal anti-inflammatory drugs

· corticosteroids

· oral anticoagulants such as warfarin, injectable heparin, antiplatelet agents or other thrombolytics such as ticlopidine

· lithium

· methotrexate

· angiotensin converting enzyme inhibitors, diuretics, beta-blockers and angiotensin II antagonists

· some antidepressants (selective serotonin reuptake inhibitors)

· pemetrexed

· ciclosporin, tacrolimus.

Interactions with food and beverages

Not applicable.

Interactions with Herbal Medicines or Alternative Therapies

Not applicable.

Use during pregnancy and lactation

Pregnancy and breast feeding

ASK YOUR DOCTOR OR YOUR PHARMACIST BEFORE TAKING ALL MEDICINAL PRODUCTS.

Pregnancy

During the first trimester (12 weeks of gestation is 12 weeks after the 1st day of your last period), your doctor may, if necessary, to prescribe the drug.

For 2.5 to 5 months of pregnancy (12 to 24 weeks of amenorrhea), this medication will only be used on the advice of your doctor and in brief dosage. Prolonged use of this medication is strongly discouraged.

After 5 months of pregnancy (beyond 24 weeks of amenorrhea), you should NOT take this medication because its effects on your child can have serious consequences, especially on a cardiopulmonary level and renal, even with a single dose.

If you are taking this medication when you are more than five months pregnant, please speak to your obstetrician gynecologist for appropriate monitoring.

feeding

This drug passes into breast milk. As a precaution, it should be avoided during breastfeeding.

Sport

Not applicable.

Effects on ability to drive or use machines

Driving and using machines:

In rare cases, taking this medicine may cause dizziness and blurred vision.

List of excipients with known effect

Important information about some of the ingredients of ADVILCAPS 200 mg soft capsule:

This medicine contains sorbitol (E420).

3. HOW TO TAKE ADVILCAPS 200 mg, soft capsule?

Instructions for proper use

The occurrence of adverse reactions can be minimized by using the lowest possible dose for the shortest duration necessary to alleviate the symptoms.

Dosage, Mode and / or route (s) of administration, Frequency of administration and Duration of treatment

Dosage

ADULT TO ADULT AND CHILD FROM 20 KG (approx. 6 years).

Painful and / or febrile conditions

In children, the usual dosage is 20 to 30 mg / kg / day in 3 doses per day (not to exceed 30 mg / kg / day).

In children from 20 to 30 kg (approximately 6 to 11 years): 1 capsule (200 mg), to be renewed if necessary after 6 hours. In all cases, do not exceed 3 capsules per day (600 mg).

In adults and children over 30 kg (approximately 11-12 years): 1 to 2 capsules (200 mg to 400 mg), to be renewed if necessary after 6 hours. In all cases, do not exceed 6 capsules per day (1200 mg).

The elderly with an increased risk of adverse effects should use the lowest possible dose for the shortest time necessary to relieve symptoms.

Do not exceed the recommended doses or the duration of treatment (3 days in case of fever, 5 days in case of pain).

The maximum dosage is 6 capsules per day (1200 mg).

Method and route of administration

Oral use.

Swallow the soft capsule, without chewing it, with a large glass of water.

Soft capsules should be taken preferably during a meal.

Frequency of Administration

Systematic catches help to avoid oscillations of pain or fever.

They should be spaced at least 6 hours.

Duration of treatment

The duration of use is limited to:

· 3 days in case of fever,

· 5 days in case of pain

If the pain persists more than 5 days or the fever more than 3 days, or if they worsen or in the event of another disorder, inform your doctor.

If you feel that the effect of ADVILCAPS 200 mg, soft capsule is too strong or too weak, talk to your doctor or pharmacist.

Symptoms and Instructions for Overdose

If you take more ADVILCAPS 200 mg, soft capsule than you should:

In case of accidental overdose or intoxication, STOP TREATMENT AND IMMEDIATELY CONSULT YOUR DOCTOR.

Instructions for omission of one or more doses

If you forget to take ADVILCAPS 200 mg, soft capsule:

Do not take a double dose to make up for the single dose that you have forgotten to take.

Risk of withdrawal syndrome

Not applicable.

4. WHAT ARE POSSIBLE SIDE EFFECTS?

Description of adverse reactions

Like all medicines, ADVILCAPS 200 mg, Soft Capsule is likely to have side effects, although not everyone is subject to it.

Drugs such as ADVILCAPS 200 mg, soft capsule may increase the risk of heart attack (myocardial infarction) or stroke.

May cause allergic reactions:

· rash: rash on the skin, itching, edema, aggravation of chronic urticaria,

· respiratory, asthma crisis,

· generalized: abrupt swelling of the face and neck with respiratory discomfort (angioedema).

In rare cases, gastrointestinal hemorrhage may occur ( see section "Take special precautions with ADVILCAPS 200 mg soft capsule" ). This is all the more frequent when the dosage used is high.

Exceptionally, there may be headaches accompanied by nausea, vomiting and neck stiffness.

Very rarely, bullous manifestations of the skin or mucous membranes (burning sensation accompanied by redness with bubbles, blisters, ulcerations) may occur.

Exceptionally, severe skin infections have been observed in cases of chicken pox.

In all these cases, you should stop treatment immediately and notify your doctor.

During treatment, there may be:

· digestive disorders: stomach upset, vomiting, nausea, diarrhea, constipation,

· dizziness, headache, rare visual disturbances, significant decrease in urine, renal insufficiency.

In all these cases, you should tell your doctor.

Exceptionally, there have been changes in liver function or blood counts (decreased white blood cells or red blood cells) that may be severe.

If you notice any side effects not listed in this leaflet, or if any of the side effects gets serious, contact your doctor or pharmacist.

5. HOW TO STORE ADVILCAPS 200 mg, soft capsule?

Keep out of the reach and sight of children.

Expiration date

Do not use after the expiry date stated on the carton.

Storage conditions

Store at a temperature not exceeding 25 ° C.

If necessary, warnings against visible signs of deterioration

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist what to do with unused medications. These measures will help protect the environment.

6. ADDITIONAL INFORMATION

Full list of active substances and excipients

What does ADVILCAPS 200 mg contain, soft capsule?

The active substance is:

Ibuprofen ................................................. .................................................. ..................................... 200 mg

For a soft capsule.

The other components are:

Macrogol 600, potassium hydroxide (50% solution).

Envelope of the capsule:

Liquid sorbitol partially dehydrated, gelatin, purified water, patent blue V (E 131), quinoline yellow (E 104).

Ink for printing:

OPACODE WHITE NSP-78-18022: SDA 35A alcohol, propylene glycol, titanium dioxide (E171), polyvinyl acetophthalate, purified water, isopropyl alcohol, macrogol 400, 28% ammonium hydroxide.

Pharmaceutical form and content

What is ADVILCAPS 200 mg, soft capsule and contents of the pack?

This medicine is in the form of a soft capsule, light green in color with "200" printed in white.

Box of 8, 10, 12, 16, 20, 24 or 30.

Not all pack sizes may be marketed.

Name and address of the marketing authorization holder and the holder of the manufacturing authorization responsible for the release of the lots, if different

Holder

PFIZER FAMILY HEALTH

23-25, avenue du Docteur Lannelongue

75014 PARIS

exploiting

PFIZER FAMILY HEALTH

23-25 ​​rue du Docteur Lannelongue

75014 PARIS

Maker

PFIZER CONSUMER MANUFACTURING ITALY SRL

VIA NETTUNENSE, 90

04011 APRILIA - LT

ITALY

Names of the medicinal product in the Member States of the European Economic Area

Not applicable.

Date of approval of the notice

The last date on which this leaflet was approved is {date}.

AMM under exceptional circumstances

Not applicable.

Internet Information

Detailed information on this medicine is available on the Afssaps website (France).

Information for health professionals only

Not applicable.

Other

ADVICE / HEALTH EDUCATION

"WHAT TO DO IN THE EVENT OF FEVER":

The normal temperature of the body is variable from one individual to another and between 36.5 ° C and 37.5 ° C.

An increase of more than 0.8 ° C is considered a fever.

In adults and children over 20 kg (approx. 6 years): If the disorder is too troublesome, you can take a medication containing ibuprofen at the indicated dosage.

With this medication, the fever should drop rapidly. However:

· if other signs appear (such as a rash),

· if the fever persists for more than 3 days or if it worsens,

· if the headache becomes violent, or in case of vomiting,

CONSULT YOUR DOCTOR IMMEDIATELY.

"WHAT TO DO IN CASE OF PAIN":

· In the absence of improvement after 5 days of treatment,

· If the pain returns regularly,

· If accompanied by fever,

· If she wakes you up at night,

CONSULT YOUR DOCTOR IMMEDIATELY.

VIDAL OF THE FAMILY

ADVILCAPS

Non-steroidal anti-inflammatory drug

ibuprofen

. Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS (summary)

ADVILCAPS 200 mg: soft capsule (light green); box of 16.
-

ADVILCAPS 400 mg: soft capsule; box of 14.
-

Pfizer Family Health Laboratory

COMPOSITION (summary)
p caps p caps
Ibuprofen 200 mg 400 mg
sorbitol + +

INDICATIONS (summary)
This drug is a non- steroidal anti-inflammatory drug ( NSAID ). It combats pain and lowers the fever. Its anti-inflammatory properties manifest in high doses.
It is used in the treatment of short duration of fever and pain (headaches, dental pain, muscle aches, painful periods ...).
The 400 mg capsules are also used in the treatment of the migraine crisis in adults, after at least medical advice.
CONTRAINDICATIONS (summary)
This medication should not be used in the following cases:
WARNING (Contents)
Prolonged treatment or overdosage of NSAIDs may result in serious adverse reactions.
Some situations should lead to further treatment only after medical advice:
  • severe heartburn or black and foul-smelling stools that may indicate irritation or bleeding of the digestive tract;
  • rash without obvious cause;
  • asthma attack ;
  • unusual and intense fatigue, or a sharp and significant decrease in the volume of urine in a person suffering from heart failure , dehydration or diuretic treatment.
Precautions are necessary in the elderly or in case of a history of stomach or duodenal ulcer or haemorrhagic risk, especially digestive ( Crohn 's disease , ulcerative colitis ).
The use of NSAIDs is not recommended in children with varicella: it may increase the risk of infectious, exceptional but potentially serious complications.
NSAIDs have an inhibitory effect on ovulation and are likely to decrease fertility in women. This effect is reversible upon discontinuation of treatment.
Some doctors consider that anti-inflammatories can decrease the effectiveness of intrauterine devices (IUDs) and expose them to an unwanted pregnancy risk. This risk is highly controversial.
Conductor: This medication may be responsible, in rare cases, for dizziness or disturbances of vision.
DRUG INTERACTIONS (summary)
This medication may interact with other medicines, including: Inform your doctor or pharmacist if you are taking a diuretic , an ACE inhibitor , an angiotensin II inhibitor , a beta-blocker, or a medicine containing ciclosporin.
PREGNANCY AND BREAST-FEEDING (summary)
Pregnancy :
Adverse effects to the unborn child have been demonstrated when NSAIDs are used during the last 4 months of pregnancy; the risk exists even with a single intake and even if the pregnancy is over term. The use of this medication is contraindicated during this period.
During the first 5 months, the effect of this medication is poorly understood: only your doctor can evaluate the possible risk of its use in your case.

Breastfeeding:
Ibuprofen passes in very low amounts in breast milk: its use at the recommended doses is possible during breastfeeding.
DIRECTIONS FOR USE AND DOSAGE (summary)
In order to limit the occurrence of digestive disorders , this medication can be taken during meals with a large glass of water. However, in the case of acute pain, the fasting catch ensures a faster effect. Catches must be spaced at least 6 hours apart.
Capsules are not suitable for children under 6 years of age. They may clog the airways if the child swallows and the capsule passes into the trachea (false route).

Usual dosage:

Pain and fever:
  • Adult and child over 30 kg (about 11 years): 1 to 2 capsules to 200 mg or 1 capsule to 400 mg, to be renewed if necessary after a minimum period of 6 hours. Do not exceed 6 capsules at 200 mg or 3 capsules at 400 mg per day.
  • Child 20 to 30 kg (approximately 6 to 11 years): 1 capsule to 200 mg, to be renewed if necessary every 6 hours. Do not exceed 3 capsules at 200 mg per day.
In the absence of medical advice, the duration of treatment should be limited to 5 days in case of pain and 3 days in case of fever.
Migraine attack:
  • Adult: 1 capsule to 400 mg, to be taken at the beginning of the crisis. There is no need to take a capsule if the effect is insufficient. On the other hand, if the symptoms reappear, it is possible to take 1 additional capsule within a minimum delay of 8 hours between the 2 catches. Do not exceed 3 days of treatment.
TIPS (summary)
The 400 mg dosage is intended for use when ibuprofen 200 mg is insufficiently effective. It can nevertheless be used from the outset in the treatment of severe pain.
Taking this medication does not dispense with the usual measures to help cede the migraine attack: lie down in a dark room.
Do not exceed the recommended dosage or duration of treatment recommended by your doctor or pharmacist to limit side effects.
This medicinal product may be freely available in certain pharmacies; nevertheless, do not hesitate to ask your pharmacist for advice.
POSSIBLE ADVERSE EFFECTS (summary)
Nausea, vomiting, gastritis .
Rarely:

GLOSSARY (summary)


NSAIDs
Abbreviation for non-steroidal anti-inflammatory drug. Family of anti-inflammatory drugs that are not derived from cortisone (steroids), and the best known of which is aspirin.


allergy
Skin reaction (itching, pimples, swelling) or general discomfort occurring after contact with a particular substance, use of a medication, or ingestion of food. The main forms of allergy are eczema, urticaria, asthma, angioedema and allergic shock (anaphylactic shock). Food allergy can also result in digestive disorders.


anemia
Reduction in the level of hemoglobin in the blood, which usually results in a decrease in the number of red blood cells. Iron is essential for the synthesis of hemoglobin. Iron deficiency during pregnancy, a vegetarian diet, abundant or repeated haemorrhage (menstruation) is a common cause of anemia. Other causes, more rare, are related to vitamin deficiencies of group B.


antecedent
Affection healed or always in evolution. The antecedent may be personal or family. The background is the history of a person's health.


antiplatelet agents
Medication that prevents the platelets from clumping and therefore the clots from forming. The oldest platelet antiaggregant is aspirin taken in small doses.
Anti-aggregants should not be confused with anticoagulants with a different mechanism of action.


anti coagulants
Medication that prevents blood from coagulating and therefore prevents clots from forming in the blood vessels.
Anticoagulants are used to treat or prevent phlebitis, pulmonary embolism, certain infarcts. They also prevent the formation of clots in the heart during rhythm disorders such as atrial fibrillation or in the case of an artificial heart valve.
There are two main types of anticoagulants:
  • oral anticoagulants, which block the action of vitamin K (antivitamin K, or AVK) and whose effectiveness is controlled by a blood test: INR (formerly TP);
  • injectable anticoagulants derived from heparin, the efficacy of which can be controlled by the blood assay of anti-Xa activity, Howell's Time (TH) or Cephalin Kaolin Time (TCK) depending on the products used. A regular dosage of blood platelets is necessary throughout the life of a heparin derivative.


anti-inflammatory
Medicine that fights against inflammation. It can be either derived from cortisone (steroidal anti-inflammatory), or not derived from cortisone (nonsteroidal anti-inflammatory or NSAID).


asthma
Disease characterized by difficulty breathing, often resulting in wheezing. Asthma, permanent or occurring by crisis, is due to a narrowing and inflammation of the bronchi.


beta blockers
Family of drugs used primarily in cardiology. They block the action of adrenaline (and other related hormones) on the heart, vessels and bronchi.


Crohn
inflammation of the intestine, which can cause ulcers and narrowing. It often becomes chronic and can be accompanied by persistent diarrhea and malnutrition.


diuretic
Medication allowing increased kidney water removal. Most often, this loss of water follows the loss of salts caused by the drug (salidiuretic).
Diuretics are mainly used in the treatment of high blood pressure, while their mechanism of action in this disease is poorly understood. They are also prescribed in acute or chronic heart failure, edema and other rarer ailments.
These drugs cause loss of sodium and potassium (except for some of them called "potassium-sparing"). Their prolonged administration therefore requires regular blood potassium control, to avoid heart problems that may result from hypokalemia (lack of potassium in the blood). Lack of sodium is another possible but less frequent consequence of the prolonged use of diuretics; it is also detected by a blood test.


duodenum
A part of the intestine into which food from the stomach penetrates.


skin rash
Appearance of pimples or plaques on the skin. These lesions can be due to a food, a drug, and translate an allergy or a toxic effect. Many viruses can also cause pimple eruptions: rubella, roseola and measles are the most common.


gastritis
Inflammation of the stomach favored by stress, tobacco, alcohol and certain drugs such as aspirin or anti-inflammatory drugs.


hemorrhage
Loss of blood from an artery or vein. Hemorrhage can be external, but also internal and go unnoticed.


angiotensin II inhibitor
These drugs are sometimes called sartans, for the names of the molecules belonging to this family end with sartan (losartan, candesartan, etc.).
This family of drugs blocks the action of angiotensin II, a substance that increases blood pressure and tires the heart.
Angiotensin II inhibitors are used to treat high blood pressure.


ACE inhibitor
This family of drugs blocks the action of an enzyme, which converts angiotensin I (naturally inactive substance) to angiotensin II. This last substance increases blood pressure and fatigue the heart.
ACE inhibitors are used to treat high blood pressure, heart failure or myocardial infarction.


heart failure
Inability of the heart to fulfill its function as a pump. The main symptoms of heart failure are fatigue and shortness of breath during an effort.


Hepatic insufficiency
Inability of the liver to perform its function, which is essentially the elimination of some waste, but also the synthesis of many biological substances essential to the body: albumin, cholesterol and coagulation factors (vitamin K, etc.).


renal failure
Inability of the kidneys to eliminate waste or medicinal substances. Advanced renal insufficiency does not necessarily result in a decrease in the amount of urine excreted. Only a blood test and creatinine dosage may reveal this disease.


lupus erythematosus
Skin disease causing redness of the central part of the face. There are two main forms: discoid lupus (only cutaneous) and disseminated lupus (associated with lesions of the deep organs).


migraine
Special headache usually affecting the right or left half of the head, often associated with a fear of light and noise.


blood count
The count measures the number of red blood cells (red blood cells), white blood cells (leukocytes) and platelets in the blood. The blood formula specifies the percentage of different white blood cells: neutrophils, eosinophils, basophils, lymphocytes, monocytes.
Abbreviation: NFS.


edema
Accumulation of water or lymph causing localized swelling.


dosage
Quantity and distribution of the dose of a drug according to the age, weight and general condition of the patient.


allergic reaction
Reaction due to hypersensitivity of the organism to a drug. Allergic reactions can take a wide variety of aspects: urticaria, angioedema, eczema, eruption of pimples resembling measles, etc. Anaphylactic shock is a generalized allergic reaction that causes discomfort due to a sudden drop in blood pressure.


ulcerative colitis
Inflammatory disease of the rectum and colon, which evolves by flare-ups. Each flare is accompanied by fever, bloody stools.


overdose
Excessive intake of a drug may result in an increase in the intensity of adverse effects or even in the development of specific adverse effects.
This overdose may result from accidental or voluntary poisoning for suicide, so consult your local Poison Control Center (listed in the appendix to the book). However, in most cases, overdose is the result of an error in the understanding of the prescription, or the search for an increase in efficacy by exceeding the recommended dosage. Finally, untimely self-medication may lead to excessive absorption of the same substance contained in different drugs. Some drugs are particularly prone to this risk because they are (wrongly) considered to be harmless: vitamins A and D, aspirin, etc. Stopping or decreasing drug intake helps to remove the disorders associated with an overdose.


crisis management
As opposed to long-term treatment, short-term and episodic treatment in the context of seizure or outbreak diseases.


transaminases
Enzymes dosed in the blood, which rate rises during some hepatitis. They are included in blood tests as SGOT and SGPT or ASAT and ALAT.


digestive disorders
Set of symptoms indicating irritation or malfunction of the digestive tract. One or more disorders may be present: nausea, vomiting, aerophagia, abdominal pain, heartburn, bloating, flatulence, diarrhea or constipation, etc. Antibiotics can promote candidiasis, often responsible for digestive disorders.


ulcer
Injury of skin, mucous membranes or cornea.
  • Leg ulcer: chronic wound due to poor circulation of blood.
  • Gastroduodenal ulcer: a localized wound in the mucosa of the stomach or duodenum due to excess acidity and very often to the presence of a bacterium (Helicobacter pylori). The ulcer is favored by stress, alcohol, smoking and certain medications (aspirin, NSAIDs, etc.).


dizziness
Symptom that can mean an impression of loss of balance (common sense) or, more strictly, a sense of rotation on oneself or the environment (medical sense).

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