150MG TABLETS 60 Endotelon

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Endotelon veinotonic is recommended in disorders of the venous circulation: heavy legs, pain, painful sensations called "impatient" at bedtime.

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The advice of your pharmacist

Partners with: Blood Energy Homeogum Sublingual Lozenge 40g

Used for : heavy legs, lymph edema, lymph edema

contains: grape seed, grape seed

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For warnings, precautions for use and against-indications, please see the instructions for use of Endotelon.

Description veinotonic Endotelon

Endotelon is a venotonic that increases the tonicity of venous walls, and a vasculoprotective which increases the resistance of small blood vessels.

Endotelon this drug is recommended in disorders of the venous circulation: heavy legs, pain, painful sensations called "impatient" at bedtime. It is also recommended in the treatment of lymphedema of the arm after radiosurgical treatment of a breast tumor, in addition to physical treatments such as elastic restraint.

Composition Endotelon

Purified extract standardized grape seed oligomeric proanthocyanidins in 150 mg for an enteric coated tablet

Excipients: microcrystalline cellulose, colloidal anhydrous silica, magnesium stearate, copolymer of methacrylic acid and ethyl acrylate (1: 1), sodium hydroxide, triethyl citrate, sucrose, gelatin, gum arabic, titanium dioxide ( E 171), talc, yellow iron oxide (E172), carnauba wax (powder).

Excipient with known effect: sucrose

Dosage of Endotelon

oral

1 tablet in the morning and 1 tablet in the evening, 20 days a month.

In lymphedema of the arm: 1 tablet in the morning and 1 tablet in the evening when administered continuously.

Cons-indications with Endotelon

Allergy to any component (oligomeric proanthocyanidins)

Not recommended for breastfeeding

Precautions

- Read the instructions carefully.
- Keep out of reach of children
- Not subject to prescription medication.

Conditioning :   box of 60 tablets of enteric coated Endotelon

Warnings about medications

Attention Endotelon the drug is not a product like any other. Read the medications manual Endotélonavant to order. Do not let drugs out of reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Beware of incompatibilities on your current products.

Tell your pharmacist Online ongoing treatment to identify any incompatibilities. The order confirmation form contains a custom message field provided for this purpose.

Click here to find the Endotelon notice from this medicine on the website of the National Agency of Drug Safety and health products.

Pharmacovigilance : Declare one or effect (s) undesirable (s) connected (s) to the use of a drug Endotelon

VIDAL OF THE FAMILY

Endotelon

Vasculoprotective and veinotonic

oligomers procyanidolic

. Presentations . Composition . Indications . Warning . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS (summary)

ENDOTELON 150 mg: Gastro - resistant tablet (yellow); box of 60.
-

Laboratory

COMPOSITION (summary)
p cp
Grape seeds, purified extract standardized in procyanidolic oligomers 150 mg
Sucrose +

INDICATIONS (summary)
It is a vascular protector and a veinotonic . It stimulates the circulation of blood in the veins and combats the alteration of capillary vessels .
It is used in the symptomatic treatment:
  • heavy legs, pain, impatience and other disorders related to poor venous or lymphatic circulation;
  • of the arm edema after surgical treatment and / or radiotherapy for breast cancer, usually in addition to lymphatic drainage.
WARNING (Contents)
This drug is insufficient to prevent the risk of phlebitis in patients bedridden or plastered.
The treatment of venous insufficiency is based on specific measures such as the wearing of compression stockings.
PREGNANCY AND BREAST-FEEDING (summary)
The effect of this medication during pregnancy or lactation is not well known. The assessment of the possible risk associated with its use is individual: ask your pharmacist or doctor for advice.
DIRECTIONS FOR USE AND DOSAGE (summary)
This medication should be taken with a glass of water apart from meals.

Usual dosage:

1 tablet at 150 mg, morning and evening.
TIPS (summary)
Regular physical activity and elevation of the foot of the bed facilitate the venous and lymphatic circulation.
POSSIBLE ADVERSE EFFECTS (summary)
Rarely: allergic reaction , nausea, diarrhea, stomach pain.
Exceptionally: headaches.


GLOSSARY (summary)


enteric
Qualifies certain tablets or capsules in which the active substance is protected from the acidity of the stomach.


impatience
Painful sensations in the legs. They manifest themselves, usually during bedtime, by a feeling of discomfort, an irrepressible need to move their legs.


venous insufficiency
Incapacity of the veins of the legs to bring the blood back to the heart.


lymphatic
The lymph, a colorless liquid that circulates in specific vessels and whose accumulation causes edema.


edema
Accumulation of water or lymph causing localized swelling.


phlebitis
Inflammation of a deep vein with formation of a blood clot, usually affecting the legs. The severity of the phlebitis is related to the possibility of displacement of the clot which can migrate to the heart and then obstruct an artery of the lungs (pulmonary embolism). A paraphlebite, or superficial phlebitis, is the inflammation of a superficial vein; it is much less worrying.


allergic reaction
Reaction due to hypersensitivity of the organism to a drug. Allergic reactions can take a wide variety of aspects: urticaria, angioedema, eczema, eruption of pimples resembling measles, etc. Anaphylactic shock is a generalized allergic reaction that causes discomfort due to a sudden drop in blood pressure.


symptomatic treatment
Treatment that suppresses or alleviates the symptoms of a disease without addressing its cause.


capillary vessels
Blood vessels thinner than hair (hence their name) that irrigate the cells.


vascular
Blood vessels: arteries and veins.


veinotonic
Refers to a drug that has the property of increasing the tone of the wall.

Cliquez ici pour retrouver la notice de ce médicament sur le site de l'Agence Nationale de Sécurité du Médicament et des produits de santé.

Pharmacovigilance : Déclarer un ou des effet(s) indésirable(s) lié(s) à l'utilisation d'un médicament

NOTICE

ANSM - Last updated: 27/04/2017

Name of the medicinal product

ENDOTELON 150 mg gastro-resistant coated tablet

Grape seed extract

framed

Read this leaflet carefully before you start taking this medicine. It contains important information for your treatment.

If you have any further questions, ask your doctor or pharmacist.

· Keep this leaflet, you may need to read it again.

· If you need more information and advice, ask your pharmacist.

· If symptoms worsen or persist, consult your doctor.

· If you notice any side effects not listed in this leaflet, or if you experience any of the effects listed as serious, please tell your doctor or pharmacist.

What is in this leaflet?

1. What is ENDOTELON and when is it used?

2. What information should be known before taking ENDOTELON?

3. How to take ENDOTELON?

4. What are the possible side effects?

5. How to store ENDOTELON?

6. Package contents and other information.

1. WHAT IS ENDOTELON AND IN WHAT CASES IS IT USED?

VASCULOPROTECTOR / MEDICAMENT ACTING ON CAPILLAIRES.

(C05CX: cardiovascular system).

This drug is a veinotonic ( it increases the tonicity of the venous walls ) and a vasculoprotector ( it increases the resistance of the small blood vessels ).

It is used for:

- Relieve symptoms due to venous circulation disorders (heavy legs, pain, painful sensations called "impatience" at bedtime).

- treat lymphatic edema of the arm (infiltration of lymph in the arm support tissue) to treat after a radiosurgical treatment of a breast tumor, in addition to physical treatments such as elastic restraints.

2. BEFORE YOU TAKE ENDOTELON?

If your doctor has told you about an intolerance to some sugars, contact your doctor before taking this medicine.

Do not take Endotelon

· if you are allergic to procyanidolic oligomers (grape seed compounds) or any of the other ingredients of this medication. You can find the list of components in section 6.

· If you are breast-feeding, unless your doctor tells you otherwise.

Take special care with ENDOTELON 150 mg, coated gastro-resistant tablet:

Special warnings

If you are taking Endotelon for venous or lymphatic circulation disorders, you should combine this treatment with a healthy lifestyle. It is important to follow the following recommendations to promote venous circulation:

· avoid exposing yourself to sunlight or heat,

· Avoid standing prolonged,

· avoid overweight

· make regular long walks,

· wear suitable stocking stockings.

Taking other medicines

If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Pregnancy

If you are pregnant, you should use this medicine only on the advice of your doctor.

If you discover that you are pregnant during treatment, consult your doctor as he alone can judge the need to continue.

Ask your doctor or pharmacist for advice before taking any medicine.

feeding

Treatment is not advisable if you are breastfeeding.

Ask your doctor or pharmacist for advice before taking any medicine.

Driving and using machines

Procyanidolic oligomers have no effect on the ability to drive and use machines.

Important information about some of the ingredients of this medication

This medicine contains a sugar (sucrose).

Its use is not recommended in patients with fructose intolerance, glucose-galactose malabsorption syndrome or sucrase / isomaltase deficiency (rare hereditary diseases).

3. HOW TO TAKE ENDOTELON?

Dosage

In vein-lymphatic insufficiency: 2 tablets per day, in discontinuous administration (20 days per month).

In the lymphoedema of the arm: 2 tablets per day, in continuous administration.

Administration mode

This medication is taken orally.

Frequency of Administration

Take your tablets preferably outside meals. You will distribute the daily dose: 1 tablet in the morning and 1 tablet in the evening.

Duration of treatment

IN ALL CASES, COMPLY WITH THE ORDER OF YOUR DOCTOR STRICTLY.

If you forget to take ENDOTELON:

Take your tablet as soon as possible and continue your treatment as normal.

Do not take a double dose to make up for the missed dose.

4. WHAT ARE POSSIBLE SIDE EFFECTS?

Like all medicines, Endotelon can cause side effects, although not everybody gets them.

· Undesirable effects rarely occur:

· Allergic symptoms: urticaria, rash with or without itching, photosensitivity (skin reaction when exposed to the sun), eczema. These effects are rare and disappear when treatment is discontinued.

· stomach upset, nausea, diarrhea.

· Undesirable effects very rarely occur:

· swelling of the face, lips, tongue and / or larynx resulting in difficulty breathing or swallowing,

· swelling of the hands and feet, severe itching of the skin.

· headache.

Declaration of side effects:

If you experience any side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Centers of Pharmacovigilance - Website: www.ansm.sante.fr .

By reporting adverse reactions, you are helping to provide more information about the safety of the drug.

5. HOW TO STORE ENDOTELON?

Keep out of the reach and sight of children.

Do not use ENDOTELON 150 mg enteric coated tablets after the expiry date which is stated on the carton.

No special storage conditions.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist what to do with unused medications. These measures will help protect the environment.

6. PACKAGE CONTENTS AND OTHER INFORMATION

What ENDOTELON 150 mg contains, gastro-resistant coated tablet

The active substance is :

Grape (purified seed extract from) .......................................... ............................................... 150 mg

quantified as procyanidolic oligomers for a coated tablet.

The other components are :

Microcrystalline cellulose, anhydrous colloidal silica, magnesium stearate, methacrylic acid / ethyl acrylate copolymer, sodium hydroxide, triethyl citrate, sucrose, gelatin, gum arabic, titanium dioxide (E171), talc, yellow iron (E 172), carnauba wax.

What is ENDOTELON 150 mg Gastro-resistant coated tablets and contents of the pack

This medication is in the form of an enteric coated tablet.

Box of 20, 40 or 60 tablets. Not all pack sizes may be marketed.

Marketing Authorization Holder

CHEPLAPHARM Arzneimittel GmbH

Bahnhofstr. 1a

17498 MESEKENHAGEN

GERMANY

Marketing Authorization Operator

Cheplapharm France

105 rue Anatole France

92300 Levallois-Perret

la France

Maker

SANOFI WINTHROP INDUSTRIE

1 RUE DE LA VIERGE

AMBARES AND LAGRAVE

33565 CARBON BLANC CEDEX

or

SANOFI SPA

SS 17 KM22,

66019 SCOPPITO

ITALY

Names of the medicinal product in the Member States of the European Economic Area

Not applicable.

The last date on which this leaflet was revised is:

[to be completed later by the holder]

<{MM / YYYY}> <{YYYY month}.>

Other

Detailed information on this medicine is available on the ANSM website (France).

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