Meningococcal B Vaccine Bexsero

Meningococcal B Vaccine Bexsero View larger


Bexsero is a vaccine against meningococcal B infections

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For warnings, precautions for use and cons-indications, see the manual of Bexsero.

Description Bexsero

Bexsero Meningococcal against invasive meningococcal serogroup B
Inert vaccine
- Protein multicomponent
Adjuvant: Aluminium hydroxide
Form and presentation

Suspension for injection.

Opalescent white liquid suspension.

Composition of Bexsero

One dose (0.5 ml) contains:

1. Antigens

NHBA recombinant fusion protein (heparin-binding antigen) Neisseria meningitidis Group B, (1, 2): 50 micrograms
NadA recombinant protein (adhesin A) Neisseria meningitidis group B (1, 2): 50 micrograms
FHbp recombinant fusion protein (factor binding protein H) Neisseria meningitidis group B (1, 2): 50 micrograms
Outer membrane vesicle (OMV) of Neisseria meningitidis group B strain NZ98 / 254 measured as a proportion of the total protein containing the antigen PorA P1.4 (2): 25 micrograms

(1) produced in E. coli cells, the recombinant DNA
(2) adsorbed onto aluminum hydroxide (0.5mg Al3 +)
2. Other Products

Sodium chloride
Water for injections


Bexsero is indicated for the active immunization of subjects from the age of 2 months against invasive disease caused by meningococcal group B Neisseria meningitidis

The impact of invasive disease in different age groups and epidemiologic variability of antigens of group B strains in different geographical areas must be taken into account during vaccination. See section Pharmacodynamics for information on protection against specific strains to group B. This vaccine should be used in accordance with official recommendations.

New: Opinion of the High Council of Public Health (10.25.13) on the place of Bexsero vaccine in the prevention of invasive meningococcal B.

Dosage Bexsero

The dosage includes primary and booster vaccination.

Please consult the manual to find the table Bexsero doses depending on age.

Administration mode

The vaccine is given by deep intramuscular injection, preferably in the anterolateral aspect of the thigh in infants or the deltoid muscle of the upper arm region in older subjects.
Separate injection sites must be used if more vaccines are administered simultaneously.
The vaccine must not be injected intravenously, subcutaneously or intradermally and should not be mixed with other vaccines in the same syringe.
For instructions on handling of the vaccine prior to administration, see the instructions for Bexsero.

Warnings on drugs

Warning, the drug is not a product like any other. Read the package leaflet before ordering. Do not leave medicines within reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Beware of incompatibilities on your current products.

Please tell your online pharmacist of current treatments to identify any incompatibilities. The order confirmation form contains a custom message field provided for this purpose.

Click here to find the instructions for this drug Bexsero on the website of the National Agency of Drug Safety and health products.

Pharmacovigilance Reporting an or effect (s) Adverse (s) bound (s) use of a medicament

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