ASPIRIN 500MG TABLETS UPSA SPARKLING 20

ASPIRINE 500MG UPSA COMPRIMES EFFERVESCENTS 20 View larger

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UPSA BMS UPSA BMS

UPSA Aspirin is a drug indicated for the symptomatic treatment of pain of mild to moderate and / or febrile states.

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For warnings, the precautions and cons-indications, please see the instructions.

Description

Indications
UPSA Aspirin 500 mg 20 tablets is a drug indicated for the symptomatic treatment of mild to moderate and / or febrile states pain.
Dosage and route of administration

UPSA Aspirin 500 mg tablet is recommended for adults and children over 9 years. For children 9-13 years (30 to 40 kg), 1 tablet of 500 mg Aspirin UPSA, repeat if necessary after 6 hours. In all cases, do not exceed 4 tablets per day. For children 12 to 15 years (approximately 41 to 50 kg), 1 tablet of Aspirin 500 mg, repeated if necessary after 4 hours. In all cases, do not exceed 6 tablets per day. For adults and children over 15 years (about 50 kg), 1 tablet of 500 mg Aspirin repeat if needed after 4 hours. In all cases, do not exceed 6 tablets per day. Orally.

Composition and excipients known

Acetylsalicylic acid 500 MG. Excipients: Mannitol; Malic acid; POVIDONE; Sodium dioctylsulfosuccinate; CITRIC ACID; BAKING SODA; Disodium carbonate; Sodium saccharin; FLAVOUR LEMON; (ASCORBIC ACID; CITRAL; LEMON ESSENTIAL OIL; MALTODEXTRIN; SUCROSE; MODIFIED STARCH (E 1450)); QSP 1 effervescent tablet.

Cons-indications and warnings

Pregnancy more than 5 months; history of allergy or asthma triggered by taking sallicylés or substances near activity, such as nonsteroidal anti-inflammatory; history of allergy to other components of the tablet; peptic ulcer development; severe hepatic impairment; severe renal impairment; severe uncontrolled heart failure; risk of bleeding. Aspirin 500 mg is not recommended during pregnancy and lactation. It is essential to avoid overdose verifying the absence of acetylsalicylic acid in the composition of other drugs. Must not exceed the maximum recommended dose.

Packaging

Blister 20 tablets

Warnings on drugs

Warning, the drug is not a product like any other. Read the package leaflet before ordering. Do not leave medicines out of reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Attention to incompatibilities on products in your.

Tell your pharmacist online treatments underway to identify possible incompatibilities. The checkout form contains a custom message field provided for this purpose.

Click here to find record of the drug at the site of the National Security Agency of Medicines and Health Products.

Pharmacovigilance : Report or a related adverse event (s) (s) (s) the use of a drug

VIDAL OF THE FAMILY

ASPIRINE UPSA

Analgesic and antipyretic

. Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS (summary)

ASPIRINE UPSA 500 mg: effervescent tablet (white, orange flavoring); box of 20.
Refunded at 65%. - price: 1.46 euro (s).

ASPIRINE UPSA 1000 mg: split effervescent tablet (white, orange flavoring); box of 20.
Refunded at 65%. - price: 2,49 euro (s).

UPSA Laboratory

COMPOSITION (summary)
p cp p cp
Acetylsalicylic acid (aspirin) 500 mg 1,000 mg
Sodium 388 mg 460 mg
Lactose 1.6 g
aspartame + +

INDICATIONS (summary)
This medication contains aspirin, which has many properties: analgesic and antipyretic , but also high - dose anti-inflammatory , and blood thinning.
He is used :
  • to reduce the fever and in the treatment of various pains,
  • in the treatment of inflammatory rheumatism.
CONTRAINDICATIONS (summary)
This medication should not be used in the following cases:
WARNING (Contents)
Aspirin is not an innocuous drug. Overdosage or prolonged intake may cause serious complications.
The use of aspirin requires prior medical advice if there is a history of stomach ulcer or duodenal ulcer , even if it is old, renal insufficiency , G6PD deficiency , asthma , gout, and in women have an intrauterine device (IUD).
Avoid taking this medication during the week before dental extraction, operation or during abundant periods: increased risk of hemorrhage .
The use of aspirin in children should be prudent in the case of chicken pox or fever due to a virus (flu ...). Reye syndrome, rare but sometimes fatal, has been reported. This syndrome results in disorders of consciousness and vomiting. In case of fever due to a virus, and in the absence of medical advice, other antipyretics (paracetamol, for example) should be preferred.
This drug contains salt ( sodium ) in significant quantities.
DRUG INTERACTIONS (summary)
The interactions are of varying intensity depending on the doses of aspirin used. If you are being treated with any of the medicines listed below, do not take aspirin without the advice of your doctor or pharmacist.
Aspirin used at high doses (greater than 3 g / day) should not be combined with methotrexate (used at doses greater than 15 mg / week): increased risk of methotrexate toxicity.
Aspirin may interact with: Also tell your doctor or pharmacist if you are taking an antidiabetic , an antihypertensive medication from the family of ACE inhibitors or angiotensin II inhibitors , an antidepressant in the IRS family, a diuretic or a corticosteroid .
PREGNANCY AND BREAST-FEEDING (summary)
Pregnancy :
Adverse effects on the mother and the unborn child have been demonstrated when aspirin, like other NSAIDs , is used in the last 4 months of pregnancy; the risk exists even with a single intake and even if the pregnancy is over term.
Consequently, aside from certain very specific medical situations, aspirin can only be used on an ad hoc basis during the first 5 months, and its use is contraindicated from the 6th month.

Breastfeeding:
Aspirin passes into breast milk: it is not recommended for use in breastfeeding women.
DIRECTIONS FOR USE AND DOSAGE (summary)
1000 mg tablets are reserved for adults and children over 50 kg.
The tablets should be dissolved in a glass of water.
The drug should be taken at least 4 hours apart.

Usual dosage:

Isolated pain and fever:
  • Adult and children over 50 kg: 500 mg or 1 g (ie 1 or 2 500 mg tablets or 1 1000 mg tablet) per dose to be renewed if necessary after a minimum of 4 hours, without exceeding the dose of 3 g of aspirin per day (ie 6 tablets at 500 mg or 3 tablets at 1000 mg per day).
    In the elderly, it is preferable not to exceed the dose of 2 g of aspirin per day (4 tablets to 500 mg or 2 tablets to 1000 mg per day).
  • Child 30 to 50 kg: 60 mg per kg per day divided into 4 or 6 doses, ie 15 mg per kg every 6 hours or 10 mg per kg every 4 hours. For information :
    • 30 to 40 kg (approximately 9 to 13 years old): 1 500 mg tablet, to be renewed if necessary after 6 hours without exceeding 4 catches per day;
    • child of 41 to 50 kg (approximately 13 to 15 years): 1 tablet with 500 mg, to be renewed if necessary after 4 hours without exceeding 6 catches per day.
Without medical advice, the duration of treatment should not exceed 3 days in case of fever and 5 days in case of pain.
Rheumatic Pain:
The dosage is 3 to 6 g of aspirin per day in adults and 50 to 100 mg per kg per day in children under medical supervision.
TIPS (summary)
Many drugs contain aspirin or NSAIDs (such as ibuprofen or naproxen); be sure not to take multiple medicines containing these substances simultaneously, as a joint dose may increase the risk of adverse effects.
POSSIBLE ADVERSE EFFECTS (summary)
Gastritis , abdominal pain, bleeding from the nose or gums.
Rare and sometimes serious:
  • haemorrhage of the digestive tract: bloody vomiting, black stools, or more often imperceptible blood loss, responsible for the progressive onset of anemia ;
  • allergic: urticaria , edema , asthma .
Signs suggesting an overdose: ringing in the ears, sensation of hearing loss, headache.


GLOSSARY (summary)


NSAIDs
Abbreviation for non-steroidal anti-inflammatory drug. Family of anti-inflammatory drugs that are not derived from cortisone (steroids), and the best known of which is aspirin.


allergy
Skin reaction (itching, pimples, swelling) or general discomfort occurring after contact with a particular substance, use of a medication or ingestion of food. The main forms of allergy are eczema, urticaria, asthma, angioedema and allergic shock (anaphylactic shock). Food allergy can also result in digestive disorders.


anemia
Reduction in the level of hemoglobin in the blood, which usually results in a decrease in the number of red blood cells. Iron is essential for the synthesis of hemoglobin. Iron deficiency during pregnancy, a vegetarian diet, abundant or repeated haemorrhage (menstruation) is a common cause of anemia. Other causes, more rare, are related to vitamin deficiencies of group B.


analgesic
Medication that works against pain. Analgesics act either directly on the centers of pain in the brain or by blocking the transmission of pain to the brain.
Synonym: analgesic.


antecedent
Affection healed or always in evolution. The antecedent may be personal or family. The background is the history of a person's health.


antiplatelet agents
Medication that prevents the platelets from clumping and therefore the clots from forming. The oldest platelet antiaggregant is aspirin taken in small doses.
Anti-aggregants should not be confused with anticoagulants with a different mechanism of action.


anti coagulants
Medication that prevents blood from coagulating and therefore prevents clots from forming in the blood vessels.
Anticoagulants are used to treat or prevent phlebitis, pulmonary embolism, certain infarcts. They also prevent the formation of clots in the heart during rhythm disorders such as atrial fibrillation or in the case of an artificial heart valve.
There are two main types of anticoagulants:
  • oral anticoagulants, which block the action of vitamin K (antivitamin K, or AVK) and whose effectiveness is controlled by a blood test: INR (formerly TP);
  • injectable anticoagulants derived from heparin, the efficacy of which can be controlled by the blood assay of anti-Xa activity, Howell's Time (TH) or Cephalin Kaolin Time (TCK) depending on the products used. A regular dosage of blood platelets is necessary throughout the life of a heparin derivative.


antidepressant
Medication that works against depression. Some antidepressants are also used to combat obsessive-compulsive disorder, generalized anxiety, certain rebellious pain, enuresis, etc.
Depending on their mode of action and adverse effects, antidepressants are divided into different families: imipraminic antidepressants, serotonin reuptake inhibitors, selective or non-selective MAOIs. Finally, other antidepressants do not belong to any of these families, because they possess original properties.
The mode of action of antidepressants has two main aspects: the relief of moral suffering and the fight against inhibition which removes all will to action from the depressed. There may be a time lag between these two effects: moral suffering may persist, while the capacity for action reappears. During this short period, the risk of suicide in some depressed people can be increased. The physician takes it into account in its prescription (possible association with a tranquillizer) and it must imperatively be respected.


antidiabetic
Medicine intended to combat diabetes. There are two categories: oral antidiabetic agents (sulphonylurea, hypoglycaemic and biguanides, mainly) and insulin, which is used only as an injection.


antihypertensive
Medication that fights against excess blood pressure. The main ones are beta-blockers, diuretics, calcium channel blockers, ACE inhibitors, angiotensin II inhibitors and vasodilators.


anti-inflammatory
Medicine that fights against inflammation. It can be either derived from cortisone (steroidal anti-inflammatory), or not derived from cortisone (nonsteroidal anti-inflammatory or NSAID).


antipyretic
Medication used to lower the body temperature during bouts of fever.


asthma
Disease characterized by difficulty breathing, often resulting in wheezing. Asthma, permanent or occurring by crisis, is due to a narrowing and inflammation of the bronchi.


corticoid
Substance close to cortisone. The natural corticoids, necessary for the functioning of the organism, are made by the adrenal glands. Synthetic corticosteroids, chemical derivatives of cortisone, are used as powerful anti-inflammatory drugs.


diuretic
Medication allowing increased kidney water removal. Most often, this loss of water follows the loss of salts caused by the drug (salidiuretic).
Diuretics are mainly used in the treatment of high blood pressure, while their mechanism of action in this disease is poorly understood. They are also prescribed in acute or chronic heart failure, edema and other rarer ailments.
These drugs cause loss of sodium and potassium (except for some of them called "potassium-sparing"). Their prolonged administration therefore requires regular blood potassium control, to avoid heart problems that may result from hypokalemia (lack of potassium in the blood). Lack of sodium is another possible but less frequent consequence of the prolonged use of diuretics; it is also detected by a blood test.


duodenum
A part of the intestine into which food from the stomach penetrates.


G6PD
glucose-6-phosphate dehydrogenase deficiency, an enzyme normally present in the red blood cell. His congenital absence (deficiency) is responsible for a disease called favism; it prohibits the use of certain drugs.


Gastritis
Inflammation of the stomach favored by stress, tobacco, alcohol and certain drugs such as aspirin or anti-inflammatory drugs.


drop
Disease manifested by redness and sharp pain affecting a joint (that of the big toe most often), due to an accumulation of crystals of uric acid.


hemorrhage
Loss of blood from an artery or vein. Hemorrhage can be external, but also internal and go unnoticed.


angiotensin II inhibitors
These drugs are sometimes called sartans, for the names of the molecules belonging to this family end with sartan (losartan, candesartan, etc.).
This family of drugs blocks the action of angiotensin II, a substance that increases blood pressure and tires the heart.
Angiotensin II inhibitors are used to treat high blood pressure.


ACE inhibitors
This family of drugs blocks the action of an enzyme, which converts angiotensin I (naturally inactive substance) to angiotensin II. This last substance increases blood pressure and fatigue the heart.
ACE inhibitors are used to treat high blood pressure, heart failure or myocardial infarction.


heart failure
Inability of the heart to fulfill its function as a pump. The main symptoms of heart failure are fatigue and shortness of breath during an effort.


Hepatic insufficiency
Inability of the liver to perform its function, which is essentially the elimination of some waste, but also the synthesis of many biological substances essential to the body: albumin, cholesterol and coagulation factors (vitamin K, etc.).


renal failure
Inability of the kidneys to eliminate waste or medicinal substances. Advanced renal insufficiency does not necessarily result in a decrease in the amount of urine excreted. Only a blood test and creatinine dosage may reveal this disease.


IRS
Abbreviation for inhibitor of serotonin reuptake. See this term.


edema
Accumulation of water or lymph causing localized swelling.


phenylketonuria
An inherited disease that is characterized by the absence of an enzyme and that leads to the accumulation in the blood of a toxic product. Screening is systematic at birth. Treatment is based on a specific diet during early childhood.


dosage
Quantity and distribution of the dose of a drug according to the age, weight and general condition of the patient.


salicylates
A family of drugs, the best known of which is acetylsalicylic acid (aspirin).


salt
Chemical substance of which the best known is sodium chloride, or table salt. The diet salt does not contain sodium; this is generally replaced by potassium.


sodium
An inorganic substance which can form salts, especially with chlorine (sodium chloride, or table salt).


overdose
Excessive intake of a drug may result in an increase in the intensity of adverse effects or even in the development of specific adverse effects.
This overdose may result from accidental or voluntary poisoning for suicide, so consult your local Poison Control Center (listed in the appendix to the book). However, in most cases, overdose is the result of an error in the understanding of the prescription, or the search for an increase in efficacy by exceeding the recommended dosage. Finally, untimely self-medication may lead to excessive absorption of the same substance contained in different drugs. Some drugs are particularly prone to this risk because they are (wrongly) considered to be harmless: vitamins A and D, aspirin, etc. Stopping or decreasing drug intake helps to remove the disorders associated with an overdose.


ulcer
Injury of skin, mucous membranes or cornea.
  • Leg ulcer: chronic wound due to poor circulation of blood.
  • Gastroduodenal ulcer: a localized wound in the mucosa of the stomach or duodenum due to excess acidity and very often to the presence of a bacterium (Helicobacter pylori). The ulcer is favored by stress, alcohol, smoking and certain medications (aspirin, NSAIDs, etc.).


urticaria
Eruption of pimples on the skin, whose origin is mostly allergic. The buds look like nettles and their color varies from pale pink to red.


virus
A microscopic organism that penetrates the cells of the host, where it reproduces. Much smaller than bacteria, viruses are insensitive to antibiotics. They can sometimes be destroyed by antiviral substances.

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NOTICE

ANSM - Last updated: 23/06/2017

Name of the medicinal product

ASPIRINE UPSA 500 mg, effervescent tablet

Acetylsalicylic acid

framed

Please read this leaflet carefully before you start taking this medicine because it contains important information for you.

You should always take this medication exactly as prescribed in this leaflet or by your doctor, pharmacist or nurse.

· Keep this leaflet. You might need to read it again.

· Ask your pharmacist for advice or information.

· If you experience any of the side effects, talk to your doctor, pharmacist or nurse. This also applies to any side effects not mentioned in this leaflet. See section 4.

· You should contact your doctor if you experience no improvement or if you feel less well after 3 days in case of fever or 5 days in case of pain.

What is in this leaflet?

1. What is ASPIRINE UPSA 500 mg, effervescent tablet and in which cases is it used?

2. What information should I take before taking ASPIRINE UPSA 500 mg, effervescent tablet?

3. How to take ASPIRINE UPSA 500 mg, effervescent tablet?

4. What are the possible side effects?

5. How to store ASPIRINE UPSA 500 mg, effervescent tablet?

6. Package contents and other information.

1. WHAT IS ASPIRINE UPSA 500 mg, effervescent tablet AND WHAT IT IS USED FOR?

Pharmacotherapeutic group: OTHER ANALGESICS AND ANTIPYRETICS-ANILIDES - ATC code: N02BA01

This medicine contains aspirin.

This medication is an analgesic (it calms the pain) and an antipyretic (it lowers the fever).

It is indicated :

· in case of pain and / or fever such as headaches, flu-like conditions, dental pain, body aches.

In this indication, this presentation is reserved for the adult and the child from 30 kg (about 9 to 15 years): read the instructions carefully, chapter "Posology".

· in the treatment of certain rheumatic affections.

In this indication, this presentation is reserved for adults and children from 20 kg.

For children of different weights, there are other aspirin presentations: ask your doctor or pharmacist for advice.

You should contact your doctor if you experience no improvement or feel less well after 3 days, in case of fever or 5 days in case of pain.

2. BEFORE YOU TAKE ASPIRINE UPSA 500 mg, effervescent tablet?

Do not take ASPIRINE UPSA 500 mg, effervescent tablet:

· If you are allergic to the active substance or to any of the other ingredients of this medication mentioned in section 6.

· In case of phenylketonuria (hereditary disease detected at birth), due to the presence of aspartame.

· In case of a history of asthma caused by the administration of aspirin or a related drug (including non-steroidal anti-inflammatory drugs).

· During the last trimester of pregnancy.

· In case of an ulcer of the stomach or the duodenum in evolution.

· If you have a hemorrhagic disease or bleeding risk.

· If you have severe liver disease.

· If you have a serious kidney disease.

· If you have a serious heart disease.

· If you are taking methotrexate therapy at doses greater than 20 mg / week and when aspirin is used as a high-dose anti-inflammatory drug (≥ 1 g per dose and / or ≥ 3 g daily) treatment of rheumatic conditions, or in the treatment of fever or pain (≥ 500 mg per dose and / or <3 g daily) (see section "Other medicinal products and ASPIRINE UPSA 500 mg, effervescent tablet").

· If you are taking oral anticoagulant therapy and have a history of stomach or duodenal ulcer and when aspirin is used at high doses, as anti-inflammatory drugs (≥ 1 g per dose and / or ≥ 3 g per day), especially in the treatment of rheumatic conditions or in the treatment of fever or pain (≥ 500 mg per dose and / or <3 g daily) (see section "Other medicinal products and ASPIRINE UPSA 5 00 mg , effervescent tablet").

if in doubt, seek the advice of your doctor or pharmacist.

Warnings and Precautions

Talk to your doctor or pharmacist before taking ASPIRINE UPSA 500 mg, effervescent tablet.

· If other medicines are combined, to avoid a risk of overdose, check the absence of aspirin in the composition of other medicines.

· In case of headaches occurring during prolonged use and with high doses of aspirin, you should not increase the doses but take the advice of your doctor or pharmacist.

The regular use of analgesics, in particular several analgesics in combination, can lead to kidney damage.

· Reye syndromes (a rare but very severe disease mainly associated with neurological disorders and liver damage) have been observed in children with viral diseases and receiving aspirin.

Consequently :

o in the event of a viral illness such as chickenpox or an episode of influenza: do not administer aspirin to a child without the advice of a doctor,

o in the event of a conscious or behavioral disorder and vomiting in a child taking aspirin, tell a doctor immediately.

Aspirin should only be used after advice from your doctor :

o in case of treatment of a rheumatic disease,

o in the case of G6PD (red blood cell inheritance) deficiency, as high doses of aspirin may cause hemolysis (destruction of red blood cells),

o in the case of a history of stomach or duodenal ulcer, digestive hemorrhage or gastritis,

o in case of kidney or liver disease,

o in asthma: the onset of an asthma attack in some subjects may be related to an allergy to nonsteroidal anti-inflammatory drugs or aspirin. In this case, this drug is contraindicated,

o in case of abundant menstruation or contraception by IUD,

o in case of treatment by:

§ of oral anticoagulants, when aspirin is used at high doses in the treatment of fever or pain (≥ 500 mg per dose and / or <3 g daily) and in the absence of a history of ulcer stomach or duodenum,

§ of oral anticoagulants, when aspirin is used in low doses as an antiplatelet agent (50 to 375 mg per day) and in case of a history of stomach or duodenal ulcer,

§ nonsteroidal anti-inflammatory drugs, when aspirin is used in high doses as anti-inflammatory drugs (≥ 1 g per dose and / or ≥ 3 g per day), especially in the treatment of rheumatic diseases or in the treatment of fever or pain (≥ 500 mg per dose and / or <3 g per day),

§ glucocorticoids (except hydrocortisone as an alternative treatment), when aspirin is used at high doses as an anti-inflammatory drug (≥ 1 g per dose and / or ≥ 3 g per day), particularly in the treatment of rheumatic diseases,

§ heparins used in curative doses and / or in patients over 65 years of age, when aspirin is used at high doses as an anti-inflammatory drug (≥ 1 g per dose and / or ≥ 3 g per day) treatment of rheumatic conditions, or in the treatment of fever or pain (≥ 500 mg per dose and / or <3 g daily),

§ the drugs used in the treatment of gout,

§ acetazolamide,

§ anagrelide,

§ clopidogrel,

§ pemetrexed in subjects with low to moderate renal function,

§ ticagrelor,

§ ticlopidine,

§ uricosuric drugs (see section "Other medicines and ASPIRINE UPSA 500 mg, effervescent tablet").

· During treatment: in the case of gastrointestinal haemorrhage (blood rejection through the mouth, presence of blood in the stool, stool coloration in black), STOP TREATMENT AND CONTACT IMMEDIATELY MEDICAL OR EMERGENCY MEDICAL SERVICE .

This medicine contains aspirin. Other medicines contain it.

Make sure that you or your child do not take other medicines containing aspirin and / or nonsteroidal anti-inflammatory drugs, including medicines obtained without a prescription.

Do not combine them, so as not to exceed the recommended daily dose.

(see "Posology" and "Symptoms and Instructions for Overdose").

If the pain persists more than 5 days or the fever more than 3 days , or if there is insufficient efficacy or any other signs, do not continue treatment without the advice of your doctor.

Aspirin increases the risk of haemorrhage at very low doses even when the dose is several days old. PREVENT YOUR DOCTOR, THE SURGER, THE ANESTHESIST OR YOUR DENTIST, in case a surgical gesture, even minor, is envisaged.

At high doses used in rheumatology, it is recommended to monitor the appearance of signs of overdose: ringing in the ears, loss of hearing or dizziness. If any of these symptoms appear: SEE IMMEDIATELY A DOCTOR.

Aspirin alters uricemia (amount of uric acid in the blood).

This medicine contains sodium. This medicine contains 388.5 mg sodium per effervescent tablet. To be taken into account in patients controlling their sodium dietary intake.

IN CASE OF DOUBT, DO NOT HESITATE TO ASK FOR THE OPINION OF YOUR PHYSICIAN OR YOUR PHARMACIST.

Children and Youth

This medicine is reserved for adults and children over 30 kg in case of pain, in case of fever, and to adults and children over 20 kg in case of rheumatic disease. However it is necessary to remember that if your child is less than 1 month, medical advice is essential before using aspirin.

Ask your doctor or pharmacist for advice:

· in case of pain or in case of fever: take a dose more suitable for children under 30 kg (about 9 years),

· in case of rheumatic disease: take a dosage more suitable for children under 20 kg.

Other medications and ASPIRINE UPSA 500 mg, effervescent tablet

Inform your doctor or pharmacist if you are taking, have recently taken or may take any other medicines.

When aspirin is used at high doses as an anti-inflammatory drug (≥ 1 g per dose and / or ≥ 3 g per day), especially in the treatment of rheumatic conditions or in the treatment of fever or pain (≥ 500 mg per dose and / or <3 g per day), this medication should not be used in combination:

· with methotrexate used at doses greater than 20 mg / week,

· with oral anticoagulants and in case of a history of stomach or duodenal ulcer.

This medication MUST BE AVOIDED in association with:

· of oral anticoagulants, when aspirin is used at high doses in the treatment of fever or pain (≥ 500 mg per dose and / or <3 g daily) and in the absence of a history of ulcer stomach or duodenum,

· of oral anticoagulants, when aspirin is used in low doses as an antiplatelet agent (50 to 375 mg per day) and in case of a history of stomach or duodenal ulcer,

· nonsteroidal anti-inflammatory drugs, when aspirin is used in high doses as anti-inflammatory drugs (≥ 1 g per dose and / or ≥ 3 g per day), especially in the treatment of rheumatic diseases or in the treatment of fever or pain (≥ 500 mg per dose and / or <3 g per day),

· glucocorticoids (except hydrocortisone as an alternative treatment), when aspirin is used at high doses as an anti-inflammatory drug (≥ 1 g per dose and / or ≥ 3 g per day), particularly in the treatment of rheumatic diseases,

· heparins used in curative doses and / or in patients over 65 years of age, when aspirin is used at high doses as an anti-inflammatory drug (≥ 1 g per dose and / or ≥ 3 g per day) treatment of rheumatic conditions, or in the treatment of fever or pain (≥ 500 mg per dose and / or <3 g daily),

· the drugs used in the treatment of gout,

· acetazolamide,

· anagrelide

· clopidogrel,

· pemetrexed in subjects with low to moderate renal function,

· ticagrelor,

· ticlopidine,

· uricosuric drugs (see section "Warnings and Precautions").

In order to avoid possible interactions between several medicines, you should systematically report any other treatment in progress to your doctor or pharmacist.

ASPIRINE UPSA 500 mg, effervescent tablet with food and beverages

Not applicable.

Pregnancy, breast-feeding and fertility

If you are pregnant or breastfeeding, think you may be pregnant or plan a pregnancy, ask your doctor or pharmacist for advice before taking this medication .

Pregnancy and breast feeding

Pregnancy

· During the FIRST AND SECOND QUARTERS of your pregnancy, your doctor may be required to prescribe this medication on an ad hoc basis.

· In the THIRD QUARTER of your pregnancy, you should NOT take this medication to YOURSELF, as its effects on your child can have serious consequences, especially on the cardiopulmonary and renal planes, even with single take.

However, in very special cases , your cardiologist or gynecologist may prescribe aspirin at very low doses that are not those used in the treatment of fever or pain. In this case, strictly observe the prescription of your doctor.

feeding

Aspirin passes into breast milk, this medication is not recommended during breast-feeding.

Fertility

Not applicable.

Driving and using machines

ASPIRINE UPSA 500 mg, effervescent tablet has no effect on the ability to drive and use machines ..

ASPIRINE UPSA 500 mg, effervescent tablet contains aspartame (E951) and sodium (388.5 mg per tablet).

3. HOW TO TAKE ASPIRINE UPSA 500 mg, effervescent tablet?

Always take this medication exactly as prescribed in this leaflet or as directed by your doctor, pharmacist or nurse. Check with your doctor, pharmacist or nurse if in doubt.

Dosage

In case of pain, in case of fever:

This presentation is reserved for adults and children from 30 kg (approximately 9 years)

· For adults and children weighing more than 50 kg (from about 15 years old):

The maximum recommended daily dose is 3 g of aspirin, or 6 effervescent tablets per day.

The usual dosage is 1 500 mg effervescent tablet, to be renewed if necessary after 4 hours minimum. In case of pain or fever more intense, 2 tablets effervescent to 500 mg, to renew if necessary after 4 hours minimum, without exceeding 6 effervescent tablets per day.

· For the elderly :

The maximum recommended daily dose is 2 g aspirin, or 4 effervescent tablets per day.

The usual dosage is 1 500 mg effervescent tablet, to be renewed if necessary after 4 hours minimum. In case of pain or fever more intense, 2 tablets effervescent to 500 mg, to renew if necessary after 4 hours minimum, without exceeding 4 effervescent tablets per day.

· In children between 30 and 50 kg (approximately 9 to 15 years):

The dosage of aspirin depends on the weight of the child; the ages are mentioned for information purposes.

If you do not know the weight of the child, weigh it to give it the best dose.

Aspirin exists in many dosages, allowing the treatment to be adapted to the weight of each child.

The recommended daily dose of aspirin is approximately 60 mg / kg / day, divided into 4 or 6 doses, approximately 15 mg / kg every 6 hours or 10 mg / kg every 4 hours .

o For children weighing 30 to 40 kg (approximately 9 to 13 years), the dosage is 1 effervescent tablet per dose, to be renewed if necessary after 6 hours, without exceeding 4 effervescent tablets per day.

o For children weighing 41 to 50 kg (approximately 12 to 15 years), the dosage is 1 effervescent tablet per dose, to be renewed if necessary after 4 hours, without exceeding 6 effervescent tablets per day.

In case of rheumatic affections:

This presentation is reserved for adults and children from 20 kg.

It is necessary to follow the recommendations of your doctor.

IN CASE OF DOUBT, ASK FOR ADVICE TO YOUR DOCTOR OR YOUR PHARMACIST.

Method and route of administration

Oral use.

Drink immediately after dissolving the effervescent tablet in a large glass of water.

In addition, if your child has a fever greater than 38.5 ° C, you can improve the effectiveness of the drug treatment by:

· discover your child,

· make the drink,

· do not leave your child in a place too hot.

Frequency of Administration

In case of pain, in case of fever :

Systematic catches help to avoid oscillations of pain or fever.

· In adults and children over 15 years of age: catches must be spaced at least 4 hours apart.

· In children (30 to 50 kg, approximately 9 to 15 years of age), they should be regularly spaced, including at night, preferably 6 hours , and at least 4 hours: recommended dosage.

In case of rheumatic affections :

The spacing between sockets must be at least 4 hours.

Duration of treatment

In case of pain, in case of fever:

The duration of treatment is limited:

· to 5 days in case of pain,

· at 3 days in case of fever.

If the pain persists more than 5 days or fever more than 3 days, if it worsens, do not continue treatment without the advice of your doctor or pharmacist.

In case of rheumatic affections:

Follow your doctor's advice.

If you take more ASPIRINE UPSA 500 mg, effervescent tablet than you should

During the course of the treatment, it is possible that there may be ringing in the ears, a feeling of hearing loss, headache, dizziness, usually as an overdose of aspirin.

TREATMENT AND PREVENTION OF A DOCTOR MUST BE INTERRUPTED.

In case of accidental poisoning (especially frequent in young children), CONSULT IMMEDIATELY A DOCTOR.

If you forget to take ASPIRINE UPSA 500 mg, effervescent tablet

Do not take (or give your child) double dose to compensate for the single dose you have forgotten to take (or give to your child).

If you stop taking ASPIRINE UPSA 500 mg, effervescent tablet

Not applicable.

4. WHAT ARE POSSIBLE SIDE EFFECTS?

Like all medicines, this medicine may cause side effects, although not everybody gets them.

Immediately stop treatment and tell your doctor if:

· digestive haemorrhages (see section "Warnings and Precautions"). These are all the more frequent because the dosage used is high,

· allergic reactions such as rash, asthma attack, angioedema (facial urticaria with respiratory discomfort),

· headache, dizziness: these signs usually reflect an overdose of aspirin.

· Reye syndrome (onset of consciousness or behavioral disorder and vomiting) in a child with viral disease and receiving aspirin (see section "Warnings and Precautions").

Tell your doctor if you have abdominal pain, nosebleeds or gums.

Cases of stomach ulcers have been reported.

Declaration of side effects

If you experience any side effects, talk to your doctor, pharmacist or nurse. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Centers of Pharmacovigilance - Website: www.ansm.sante.fr

By reporting adverse reactions, you are helping to provide more information about the safety of the drug.

5. HOW TO STORE ASPIRINE UPSA 500 mg, effervescent tablet?

Keep this medicine out of the reach and sight of children.

Do not use this medicine after the expiry date which is stated on the package. The expiry date refers to the last day of that month.

Store at a temperature below 25 ° C and away from moisture.

Do not throw any medicines into drains or rubbish. Ask your pharmacist to remove any medications you are no longer using. These measures will help protect the environment.

6. PACKAGE CONTENTS AND OTHER INFORMATION

What ASPIRINE UPSA 500 mg contains: effervescent tablet

· The active substance is:

Acetylsalicylic acid ................................................ .................................................. ..... 500.0 mg

For an effervescent tablet.

· The other components are:

Sodium bicarbonate, anhydrous citric acid, anhydrous monosodium citrate, anhydrous sodium carbonate, aspartame, polyvidone, polyvinylpyrrolidone, orange flavor.

What is ASPIRINE UPSA 500 mg, effervescent tablet and contents of the pack

This medication is in the form of an effervescent tablet. Box of 20 or 32.

Marketing Authorization Holder

UPSA SAS

3, RUE JOSEPH MONIER

92500 RUEIL MALMAISON

Marketing Authorization Operator

UPSA SAS

3, RUE JOSEPH MONIER

92500 RUEIL MALMAISON

Maker

UPSA SAS

304, AVENUE OF DOCTOR JEAN BRU

47000 AGEN

or

UPSA SAS

979, AVENUE DES PYRENEES

47520 THE PASSAGE

Names of the medicinal product in the Member States of the European Economic Area

Not applicable.

The last date on which this leaflet was revised is:

[to be completed later by the holder]

{month YYYY}.

Other

Detailed information on this medicine is available on the ANSM website (France).

Health Education Council:

The normal body temperature varies from person to person and ranges from 36 ° C to 37 ° C. A rise in temperature above 38 ° C may be considered a fever.

This medication is intended for adults and children up to 30 kg in case of pain and / or fever such as headaches, flu-like conditions, dental pain, aches; and is intended for the adult and the child from 20 kg in the treatment of certain rheumatic affections.

If the disorders that the fever causes are too troublesome, you can take this drug that contains paracetamol in accordance with the indicated dosages.

To avoid any risk of dehydration, consider drinking frequently.

With this medication, the fever should drop rapidly. However :

· if other unusual signs appear,

· if the fever persists for more than 3 days or if it worsens,

· if the headache becomes violent, or in case of vomiting.

CONSULT YOUR DOCTOR IMMEDIATELY.

WHAT TO DO IF PAIN:

The intensity of the perception of pain and the ability to resist it vary from person to person.

· If there is no improvement after 5 days of treatment,

· if the pain is violent, unexpected and occurs suddenly (including severe pain in the chest) and / or reverses regularly,

· if accompanied by other signs such as general malaise, fever, unusual swelling of the painful area, decreased strength in a limb,

· if it wakes you up at night.

CONSULT YOUR DOCTOR IMMEDIATELY.

Historically specialists in the fight against pain and self-medication, the UPSA laboratories (Scientific Applied Pharmacology Union) were created in Agen in 1935 by Dr Camille Bru.
Built in Bristol-Myers Squibb in 1994, the UPSA Company has given way since the UPSA brand. Through the brand UPSA, Bristol-Myers Squibb is currently the only company of the drug to provide a full range of three orders of analgesics, aspirin to morphine.
This diversity allows to apply to all patients - from infants to the elderly - and suggest treatments adapted to all types of pain. Cough, cold, flu symptoms, digestion, shape, sleep disorders: through its range of self-medication, UPSA develops and makes available drugs for pain daily.
Because health moves, the UPSA brand is in constant pursuit of innovation. The pharmaceutical development center based on the site UPSA Agen allows it to adapt to the changing needs of patients with whom she has forged a relationship of trust. Leader of family medication, UPSA brand is constantly trying to help them in their daily health, the quality and accessibility of its products. These values ​​are of UPSA, in France as in Europe, the health everyday ally.

Aspirin Pharmacy Online: Order your aspirin in your medicine bio online.


Aspirin is the active ingredient of different drugs as Aspégic®, Aspro®, etc. On Care and nature, your pharmacy online pharmacy, so you will find different packages and dosages of aspirin. Aspirin has four properties. Low or medium dose (500 mg to 2 g per day) is an analgesic (relieves pain) and an antipyretic (fever calm). At higher, and under medical advice dose, an anti-inflammatory. Aspirin is also used to prevent the formation of blood clots.

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