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ASPEGIC 20 500MG PACKS
Over-the-counter medication

ASPEGIC 20 500MG PACKS

Brand : Sanofi Aventis Sanofi Aventis
€3.00 EXCL. VAT €3.06 INCL. VAT
In stock
Reference : 3400931226895
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The Aspégic 500mg is an analgesic that relieves pain and antipyretic that lowers fever. This medicine contains aspirin, and is indicated in cases of pain and / or fever such as headaches, flu symptoms, dental pain, stiffness

ASPEGIC 500MG SACHETS 20  

For warnings, precautions for use and contraindications, please consult the instructions for use.

Description

Aspégic 500mg is an analgesic which   calms the pain , and an antipyretic which   lowers the fever . This medicine contains   aspirin , and is indicated for pain and / or fever   such as headache, flu-like illness, dental pain, body aches
It is also used in the   treatment of certain rheumatic affections.

Reserved for adults and children over 30kg.

Symptoms of influenza-like illness are very similar to those of the flu or other acute infectious diseases: fever, headache, discharge, nasal congestion, chills, fatigue, slight aches, sneezing. Although the effects felt are more pronounced than for a cold, they are less pronounced than for a real flu and usually last only a few days.

Composition

  • DL-Lysine acetylsalicylate corresponding to acetylsalicylic acid 500mg for one sachet
  • Excipients: glycine, tangerine flavor (including lactose), ammonium glycyrrhizate.

using advice

Dosage:

  • Children from 30 to 40 kg (around 9 to 13 years old) : 1 sachet per dose, to be renewed if necessary after 6 hours, without exceeding 4 sachets per day
  • Children 41 to 50 kg (around 12 to 15 years old) : 1 sachet per dose, to be renewed if necessary after 4 hours, without exceeding 6 sachets per day
  • Adults and children over 50kg (around 15 years) : 1 to 2 sachets of 500mg, to be renewed if necessary for 4 hours minimum, without exceeding 6 sachets per day
  • Elderly subjects : 1 to 2 sachets per dose, to be renewed if necessary after 4 hours, without exceeding 4 sachets per day.

Precautions for use

Contraindications:

  • Allergy to one of the components, pregnancy, ulcer and hemorrhagic disease, severe liver, kidney, heart disease, treatment with anticoagulants and methotrexate.

Oral use

Read the instructions carefully
.

Conditioning

Box of 20 sachets

Warnings on pain relievers

Attention, the drug is not a product like the others. Read the package leaflet carefully before ordering. Keep medicines out of the reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Beware of incompatibilities on your current products.

  • Please inform your online pharmacist of the treatments in progress in order to identify any incompatibilities. The order validation form contains a personalized message field provided for this purpose.
  • Click here to find the leaflet for this medication on the website of the National Agency for the Safety of Medicines and Health Products.

Pharmacovigilance Report an adverse drug reaction(s)

Download PDF leaflet

NOTICE

ANSM - Last updated: 31/07/2017

Name of the medicinal product

ASPEGIC 500 mg powder for oral solution in sachet-dose

DL-Lysine Acetylsalicylate

framed

Please read this leaflet carefully before you start taking this medicine because it contains important information for you.

You should always take this medication exactly as prescribed in this leaflet or by your doctor or pharmacist.

· Keep this leaflet. You might need to read it again.

· Ask your pharmacist for advice or information.

· If you experience any of the side effects, talk to your doctor, or your pharmacist. This also applies to any side effects not mentioned in this leaflet. See section 4.

· You should contact your doctor if you experience no improvement or feel less well after 3 days.

Do not use this medication for children.

What is in this leaflet?

1. What is ASPEGIC 500 mg powder for oral solution in sachet-dose and in which cases it is used?

2. What should I tell you before taking ASPEGIC 500 mg powder for oral solution in a sachet-dose?

3. How to take ASPEGIC 500 mg powder for oral solution in sachet-dose?

4. What are the possible side effects?

5. How to store ASPEGIC 500 mg powder for oral solution in a sachet-dose?

6. Package contents and other information.

1. WHAT IS ASPEGIC 500 mg powder for oral solution in a sachet-dose AND WHAT IT IS USED FOR?

Pharmacotherapeutic group: OTHER ANALGESICS AND ANTIPYRETICS - ATC code: N02BA01.

This medicine contains aspirin. Aspirin belongs to the family of non-steroidal anti-inflammatory drugs.

Aspirin can be used to calm pain (analgesic), lower fever (antipyretic) and / or decrease inflammation.

ASPEGIC 500 mg powder for oral solution in sachet-dose contains 500 mg of aspirin.

He is used :

· In case of pain and / or fever such as headaches, flu-like conditions, dental pain, muscle pain in adults and children over 30 kg (approximately 9 to 15 years)

· In the treatment of certain rheumatic diseases in adults and children over 20 kg (about 6 years) after medical advice . Medical follow-up is necessary.

2. BEFORE YOU TAKE ASPEGIC 500 mg powder for oral solution in sachet-dose?

If your doctor has told you about an intolerance to some sugars, contact your doctor before taking this medicine.

Never take ASPEGIC 500 mg powder for oral solution in sachet-dose:

· If you are allergic (hypersensitive) to aspirin or any of the other ingredients of ASPEGIC 500 mg powder for oral solution in sachet-dose mentioned in section 6.

· If you are allergic (hypersensitive) to a drug of the same family as aspirin (non-steroidal anti-inflammatory drugs).

· If you have ever had asthma caused by taking aspirin or medication from the same family.

· If you are currently suffering from an ulcer of the stomach or duodenum.

· If you have any bleeding or if your doctor has identified a risk of bleeding in your area.

· If you have severe liver, kidney or heart disease.

· in pregnancy from the beginning of the 6th month (beyond 24 weeks of gestation) for doses of aspirin above 100 mg daily.

· If you are taking any other medicines, make sure that the combination with ASPEGIC 500 mg powder for oral solution in a sachet-dose is not contraindicated (see section '' Other medicines and ASPEGIC 500 mg powder for solution drinkable in sachet-dose '').

· If you have a mastocytosis (disease of the cells involved in allergic reactions) because there is a risk of severe allergic reactions.

IN CASE OF DOUBT, DO NOT HESITATE TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.

Warnings and Precautions

Before using ASPEGIC 500 mg powder for oral solution in sachet-dose

ASPEGIC 500 mg powder for oral solution in sachet-dose is available without a prescription. However, you should consult your doctor before taking this medication if you:

· rheumatic diseases,

· inherited red blood cell disease, also known as G6PD deficiency (as high doses of aspirin may cause destruction of red blood cells),

· history of stomach or duodenal ulcer or inflammation of the stomach (gastritis),

· history of digestive bleeding (vomiting of blood or presence of blood in the stool),

· kidney or liver disease,

· abundant rules,

· if you are already taking another anti-inflammatory or anticoagulant treatment (see "Other medicines and ASPEGIC 500 mg powder for oral solution in sachet-dose" for more details)

· viral disease, in particular varicella or influenza-like syndrome: cases of Reye's syndrome (rare, very severe disease, associating mainly neurological disorders and liver damage) have been observed in children with viral disease and receiving aspirin.

If your child is less than one month old, you should first consult your doctor before using any medicine containing aspirin, regardless of dosage.

During treatment in children

This dosage is suitable for adults and children over 30 kg (from about 9 years) in case of pain or fever and for adults and children over 20 kg (from of about 6 years) in case of rheumatism. For children of different weights, there are other aspirin presentations with a more appropriate dosage. Do not hesitate to ask your doctor or pharmacist for advice.

During treatment, consult your doctor immediately if you have:

· (see section "Before using ASPEGIC 500 mg powder for oral solution in a sachet-dose"),

· bleeding or pain in the abdomen,

· an asthma attack. This may be a sign of an allergy to aspirin or a nonsteroidal anti-inflammatory drug.

If prolonged administration of high doses of analgesics is required, you should not increase the doses of ASPEGIC 500 mg powder for oral solution in a sachet-dose in case of headaches.

Regular use of pain-relieving drugs can lead to kidney complications.

If you have to undergo an operation

Aspirin increases the risk of bleeding even at very low doses, even when taking this drug is several days old.

Tell your doctor, surgeon, anesthesiologist or dentist about the use of this medication if you are undergoing any operation or intervention, even a minor one.

Blood tests

Tell your doctor if you need to take a blood test because aspirin can alter the level of uric acid in the blood.

Children and Youth

Not applicable.

Other medicines and ASPEGIC 500 mg powder for oral solution in sachet-dose

Zone de Texte: This medicine contains aspirin. You should not take another medication containing aspirin or other medicines in the same family (also known as nonsteroidal anti-inflammatory drugs such as ibuprofen) at the same time. The combination of these medicines with ASPEGIC 500 mg powder for oral solution in a sachet-dose may lead to an overdose and increase the risk of adverse effects. Read carefully the leaflets for other medicines you are taking to make sure that these medicines do not contain aspirin or nonsteroidal anti-inflammatory drugs.

Never take large doses of ASPEGIC 500 mg powder for oral solution in a sachet-dose (see section '' Dosage ''):

· If you are taking doses greater than 20 mg / week of methotrexate (a drug used to treat certain cancers and rheumatism).

· If you are taking an oral anticoagulant (a medicine used to thin the blood) and you have a history of stomach ulcer or duodenal ulcer.

Unless otherwise advised by your doctor, you should not take:

· high doses of ASPEGIC 500 mg powder for oral solution in sachet-dose (see paragraph '' Dosage '') if you already take:

o an oral anticoagulant or a heparin (medicines used to thin the blood),

o a non-steroidal anti-inflammatory drug or a corticosteroid (drugs used to treat a rheumatic disease, pain or inflammation).

· low doses of ASPEGIC 500 mg powder for oral solution in sachet-dose (50 to 375 mg per day) if you are already taking:

o an oral anticoagulant (drug used to thin the blood) and has a history of stomach or duodenal ulcer.

· ASPEGIC 500 mg powder for oral solution in a sachet-dose regardless of dose, if you are already taking a medication containing:

o ticlopidine or clopidogrel (medicines used to thin the blood),

o benzbromarone or probenecid (drugs used to treat gout),

o levothyroxine (medication used to treat insufficiency of thyroid gland secretion),

o pemetrexed (medication to treat certain cancers),

o anagrelide (a drug used to decrease the number of platelets in the blood),

o defibrotide (a drug used to treat a condition in which blood vessels in the liver are damaged and obstructed by blood clots),

o acetazolamide (a drug used to reduce eye pressure or the level of carbon dioxide in the blood),

o ticagrelor (medication used to prevent platelet aggregation).

Varicella vaccine : It is recommended to wait 6 weeks after vaccination before taking this medication.

Inform your doctor or pharmacist if you are taking, have recently taken or may take any other medicines.

ASPEGIC 500 mg powder for oral solution in sachet-dose with food, drink and alcohol

Alcohol use should be avoided during treatment due to increased risk of gastrointestinal injury.

Pregnancy, breast-feeding and fertility

If you are pregnant or breastfeeding, think you may be pregnant or plan a pregnancy, ask your doctor or pharmacist for advice before taking any medicine.

Pregnancy

Low doses, up to 100 mg daily :

Throughout pregnancy, if necessary, your specialist physician may prescribe aspirin at very low doses (less than or equal to 100 mg per day) in exceptional circumstances requiring specialized monitoring. If this is the case, it is very important to strictly follow your doctor's prescription, without exceeding the prescribed doses, and NOT to take ANY other medicine containing aspirin (including non-prescription drugs).

For doses above 100 mg per day:

· from 0 to 5 months of pregnancy (up to the 24th week of amenorrhea), your doctor should not prescribe this medicine unless absolutely necessary. In this case, the dose should be as low as possible and the treatment time should be as short as possible.

· from 6 months to the end of pregnancy (from the 25th week of amenorrhea), this medication is contraindicated, you should NEVER take this medication because its effects on your child can have serious consequences even fatal, especially on a cardiopulmonary and renal plan and this even with a single intake.

If you are taking this medication while you are pregnant, talk to your obstetrician gynecologist immediately so that appropriate monitoring is available.

feeding

Aspirin passes into breast milk, this medication is not recommended during breast-feeding.

Ask your doctor or pharmacist for advice before taking any medicine.

Fertility

It has been proven that this drug can decrease female fertility by acting on ovulation. This effect is reversible upon discontinuation of treatment.

Sport

Not applicable.

Driving and using machines

Not applicable.

ASPEGIC 500 mg powder for oral solution in sachet-dose contains lactose.

This medication contains a sugar (lactose) which decomposes into galactose and glucose. Its use is not recommended in patients with galactose intolerance, Lapp lactase deficiency or glucose or galactose malabsorption syndrome (rare hereditary diseases).

If your doctor has already told you that you have an intolerance to some sugars, contact your doctor before taking this medicine.

3. HOW TO TAKE ASPEGIC 500 mg powder for oral solution in sachet-dose?

In case of pain, in case of fever :

This presentation is reserved for adults and children from 30 kg (approximately 9 to 15 years).

The dosage of aspirin depends on the weight of the child; the ages are mentioned for information purposes.

If you do not know the weight of the child, weigh it to give it the best dose.

Aspirin exists in many dosages, allowing the treatment to be adapted to the weight of each child.

The recommended daily dose of aspirin is approximately 60 mg / kg / day, divided into 4 or 6 doses, approximately 15 mg / kg every 6 hours or 10 mg / kg every 4 hours .

For children weighing 30 to 40 kg (approximately 9 to 13 years), the dosage is 1 sachet per dose, to be renewed if necessary after 6 hours, without exceeding 4 sachets per day .

For children weighing 41 to 50 kg (approximately 12 to 15 years), the dosage is 1 sachet per dose, to be renewed if necessary after 4 hours, without exceeding 6 sachets per day .

For adults and children weighing more than 50 kg (from about 15 years):

· the maximum recommended daily dose is 3 g of aspirin, ie 6 sachets per day.

· The usual dosage is from 1 sachet to 500 mg, to be renewed if necessary after 4 hours minimum.

· In case of severe pain or fever , 2 sachets to 500 mg, to be renewed if necessary after 4 hours minimum, without exceeding 6 sachets per day.

For the elderly :

· the recommended maximum daily dose is 2 g of aspirin, ie 4 sachets per day.

· The usual dosage is from 1 sachet to 500 mg, to be renewed if necessary after 4 hours minimum.

· In more severe pain or fever , 2 sachets at 500 mg, to be renewed if necessary after 4 hours minimum, not to exceed 4 sachets per day.

In case of rheumatic diseases, after medical advice :

This presentation is reserved for adults and children over 20 kg (about 6 years).

Your doctor will tell you how much to take.

Method and route of administration

This medication is used orally.

Pour the contents of the sachet into a glass and add a small amount of drink (eg water, milk, fruit juice).

Frequency of Administration

Taken at regular intervals, avoid peaks of fever or pain.

In adults : catches should be regularly spaced at least 4 hours apart.

In children : catches should be regularly spaced, including at night , preferably 6 hours and at least 4 hours.

In case of rheumatic affections: the spacing between catches must be at least 4 hours.

Duration of treatment

The duration of treatment is limited:

· at 5 days in case of pain,

· at 3 days in case of fever.

In case of rheumatic diseases, your doctor will tell you how long you should take this medication.

Stop treatment and see your doctor immediately:

· if the pain persists more than 5 days or the fever lasts more than 3 days,

· if the pain or fever get worse,

· if you find that the treatment is not effective enough,

· or if any new signs occur (eg stiff neck, diarrhea, vomiting ...).

If you take more ASPEGIC 500 mg powder for oral solution in a sachet-dose than you should:

Consult your doctor immediately (especially if it is a child who has taken this medication accidentally).

Overdose can be fatal, especially in children. The main symptoms of poisoning are: ringing in the ears, a feeling of hearing loss, headaches, dizziness, or even more severe fever, severe hypoglycemia (lowering of sugar levels in the blood), rapid fall in blood pressure, accelerated breathing and loss of consciousness (coma).

If these signs occur, you should immediately stop treatment and go to a hospital for treatment.

Lung edema not associated with heart failure can occur in acute and chronic overdose with aspirin (see 4. What are the side effects?). This edema can be fatal in case of overdose.

If you forget to take ASPEGIC 500 mg powder for oral solution in sachet-dose:

Do not take a double dose to make up for the single dose that you have forgotten to take.

If you stop taking ASPEGIC 500 mg powder for oral solution in sachet-dose:

Not applicable.

4. WHAT ARE POSSIBLE SIDE EFFECTS?

Like all medicines, ASPEGIC 500 mg powder for oral solution in sachet-dose may cause side effects, although not everybody gets them.

· Ulceration of the esophagus, stomach, and intestine, perforation of digestive ulcer, perforation of the intestine.

These reactions may or may not be associated with visible or non-visible gastrointestinal bleeding (black stools, stool blood, or oral rejection), regardless of the dose of aspirin, and in patients with or without warning signs or of serious gastrointestinal history. High doses increase the risk of bleeding.

· Life-threatening bleeding (hemorrhage)

· Cerebral haemorrhage (bleeding in the brain) that can be life-threatening, especially in the elderly. If this happens, tell your doctor immediately.

· Decrease in the number of platelets in the blood.

· Destruction of red blood cells (haemolytic anemia) in patients with G6PD deficiency.

· Abnormally low levels of certain blood cells (pancytopenia, bicytopenia, aplastic anemia), depletion of blood cell production (medullary insufficiency), abnormally low levels of certain white blood cells that can lead to serious infections (leucopenia, neutropenia, agranulocytosis).

· Allergic reaction: pimples and / or redness on the skin, hives, abrupt swelling of the face or neck, which can lead to difficulty breathing (angioedema), abrupt malaise with a significant drop in blood pressure (anaphylactic shock).

· Rash in round red patches with itching and burning sensation, leaving colored spots and appearing in the same places when the drug is resumed.

· Ringing in the ears, sensation of hearing loss, headache and dizziness. This may be an overdose,

· Reye Syndrome (onset of consciousness or behavioral disorder and vomiting) in a child with viral disease and receiving aspirin (see section 2 "Warnings and Precautions").

· Inflammation of blood vessels may be associated with involvement of joints, kidney, skin and gastrointestinal tract.

· Increased liver enzymes, liver damage (mainly liver cells).

· Chronic liver disease (chronic hepatitis),

· Acute inflammation of the pancreas during an allergic reaction related to acetylsalicylic acid.

· Edema (swelling due to fluid build-up in tissues) if you are taking high doses of ASPEGIC 500 mg powder for oral solution in a sachet-dose .

· Lung edema not related to heart failure in long-term use and in the context of an allergic reaction to aspirin.

· Localized pain in the chest that can radiate to the left shoulder and jaw of allergic origin (Kounis syndrome).

· Kidney disease (renal failure).

In all cases, stop treatment immediately and seek prompt medical attention.

Other possible side effects:

· Abdominal pain.

· Bleeding (nose, gums), small red spots on the skin (purpura).

· Inflammation of the esophagus, stomach, duodenum and colon.

· Presence of blood in the sperm (hematospermia).

In these cases, you should consult your doctor.

Declaration of side effects

If you experience any side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Centers of Pharmacovigilance - Website: www.ansm.sante.fr

By reporting adverse reactions, you are helping to provide more information about the safety of the drug.

5. HOW TO STORE ASPEGIC 500 mg powder for oral solution in a sachet-dose?

Keep this medicine out of the reach and sight of children.

Do not use this medicine after the expiry date which is stated on the carton. The expiry date refers to the last day of that month.

Store at a temperature not exceeding 25 ° C and keep the sachets in the outer carton, protected from moisture.

Do not throw any medicines into drains or rubbish. Ask your pharmacist to remove any medications you are no longer using. These measures will help protect the environment.

6. PACKAGE CONTENTS AND OTHER INFORMATION

What ASPEGIC 500 mg contains, powder for oral solution in sachet-dose

· The active substances are:

DL-Lysine Acetylsalicylate ............................................. .............................................. 900 mg

(Corresponding amount of acetylsalicylic acid ............................................ ............ 500 mg)

For a sachet-dose.

· The other components are: glycine, mandarin aroma, ammonium glycyrrhizate.

What is ASPEGIC 500 mg powder for oral solution in sachet-dose and contents of the pack

Powder for oral solution. Box of 10, 15, 20, 30 and 50 of sachets-dosages.

Not all pack sizes may be marketed.

Marketing Authorization Holder

SANOFI AVENTIS FRANCE

82 AVENUE RASPAIL

94250 GENTILLY

Marketing Authorization Operator

SANOFI AVENTIS FRANCE

82 AVENUE RASPAIL

94250 GENTILLY

Maker

SANOFI WINTHROP INDUSTRIE

196 AVENUE DU MARECHAL JUNE

45200 AMILLY

Names of the medicinal product in the Member States of the European Economic Area

Not applicable.

The last date on which this leaflet was revised is:

{month YYYY}.

Other

Detailed information on this medicine is available on the ANSM website (France).

Health Education Council:

WHAT TO DO IN CASE OF FEVER

A child is considered to have a fever when the temperature exceeds 38 ° C.

Fever is a natural and frequent reaction of the body to fight infections, it is very rare that it is the only sign of a serious illness or that it leads to complications.

What has to be done :

Generally it is only above 38.5 ° C that treatment is envisaged; however this should not be systematic, especially if the fever is well supported by the child.

1) Before giving a medication for fever, always:

· remove blankets and superfluous layers of clothing,

· present often to drink to the child,

· do not overheat the room (about 18-20 ° C).

These 3 simple measures are sufficient in many cases to lower the fever.

Other measures exist (warm baths, ice packs, wet wraps ...), they are not necessarily more effective and will be considered only if they do not increase the child's evil being.

2) Secondly, the child may be given a fever medication (medication called antipyretic).

Read carefully the paragraph "What to know before taking ASPEGIC 500 mg powder for oral solution in a sachet-dose".

How should a fever medicine be used?

· respect the doses and delays between catches,

· give only one medication (do not combine or alter medications differently without medical advice),

· check that the child does not otherwise receive the same medicine (syrup, sachets, suppositories ...) or under another brand name.

If the fever persists for several days, if new signs (in particular stiffness of the neck, diarrhea, vomiting ...) or indicating that the fever is badly supported (child slaughtered, losing its reactivity ...), you must not do not hesitate to consult a doctor.

WHAT TO DO IF PAINFUL

You should consult a doctor:

· if you do not feel any improvement after 5 days of treatment,

· if the pains return regularly,

· if accompanied by fever,

· if they awaken your child at night.

VIDAL OF THE FAMILY

aspegic

Analgesic and antipyretic

lysine acetylsalicylate

. Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS (summary)

ASPÉGIC Infant 100 mg: powder for oral solution (mandarin flavoring); box of 20 bags.
Refunded at 65%. - price: 1,38 euro (s).

ASPÉGIC Enfant 250: powder for oral solution (mandarin flavoring); box of 20 bags.
Refunded at 65%. - price: 1.44 euro (s).

ASPÉGIC 500: powder for oral solution (mandarin flavoring); box of 20 bags.
Refunded at 65%. - price: 1,69 euro (s).

ASPÉGIC 500: powder for oral solution (mandarin flavoring); box of 30 bags.
-

ASPÉGIC Adult 1000: powder for oral solution (mandarin flavoring); box of 15 sachets.
-

ASPÉGIC Adult 1000: powder for oral solution (mandarin flavoring); box of 20 bags.
Refunded at 65%. - price: 3,06 euro (s).

ASPÉGIC Adult 1000: powder for oral solution (mandarin flavoring); box of 30 bags.
-

Laboratory Sanofi-Aventis France

COMPOSITION (summary)
p sachet p sachet
Lysine Acetylsalicylate 180 mg 450 mg
or acetylsalicylic acid (aspirin) 100 mg 250 mg

p sachet p sachet
Lysine Acetylsalicylate 900 mg 1.8 g
or acetylsalicylic acid (aspirin) 500 mg 1,000 mg
Lactose + +

INDICATIONS (summary)
This medication contains aspirin which has many properties: analgesic and antipyretic , but also high - dose anti-inflammatory , and blood thinning.
He is used :
  • to reduce the fever and in the treatment of various pains,
  • in the treatment of inflammatory rheumatism.
CONTRAINDICATIONS (summary)
This medication should not be used in the following cases:
WARNING (Contents)
Aspirin is not an innocuous drug. Overdosage or prolonged intake may cause serious complications.
The use of aspirin requires prior medical advice if there is a history of stomach ulcer or duodenal ulcer , even if it is old, renal insufficiency , G6PD deficiency , asthma , gout, and in women have an intrauterine device (IUD).
Avoid taking this medication during the week before dental extraction, operation or during abundant periods: increased risk of hemorrhage .
The use of aspirin in children should be prudent in case of chicken pox or fever due to a virus (flu ...). Reye syndrome, rare but sometimes fatal, has been reported. This syndrome results in disorders of consciousness and vomiting. In case of fever due to a virus, and in the absence of medical advice, other antipyretics (paracetamol, for example) should be preferred.
DRUG INTERACTIONS (summary)
The interactions are of varying intensity depending on the doses of aspirin used. If you are being treated with any of the medicines listed below, do not take aspirin without the advice of your doctor or pharmacist.
Aspirin used at high doses (greater than 3 g / day) should not be combined with methotrexate (used at doses greater than 15 mg / week): increased risk of methotrexate toxicity.
Aspirin may interact with: Also tell your doctor or pharmacist if you are taking an antidiabetic , an antihypertensive medication from the family of ACE inhibitors or angiotensin II inhibitors , an antidepressant in the IRS family, a diuretic or a corticosteroid .
PREGNANCY AND BREAST-FEEDING (summary)
Pregnancy :
Adverse effects on the mother and the unborn child have been demonstrated when aspirin, like other NSAIDs , is used in the last 4 months of pregnancy; the risk exists even with a single intake and even if the pregnancy is over term.
Consequently, aside from certain very specific medical situations, aspirin can only be used on an ad hoc basis during the first 5 months, and its use is contraindicated from the 6th month.

Breastfeeding:
Aspirin passes into breast milk: it is not recommended for use in breastfeeding women.
DIRECTIONS FOR USE AND DOSAGE (summary)
This medication is taken preferably during meals. The effect will be faster if taken on an empty stomach. The catch must be spaced at least 4 hours apart.
Pour the contents of the sachet into a glass and add water, milk or fruit juice.
The 100 mg sachets are reserved for children from 6 to 22 kg.
The 250 mg sachets are reserved for children from 15 to 50 kg.
The 500 mg sachets are reserved for adults and children from 30 kg.
The 1000 mg sachets are reserved for adults and children up to 50 kg.

Usual dosage:

Isolated pain, fever:
  • Adult and children over 50 kg: 500 mg or 1 g (ie 1 or 2 sachets to 500 mg or 1 sachet to 1000 mg) per dose to be renewed if necessary after a minimum period of 4 hours, without exceeding the dose of 3 g of aspirin per day (ie 6 sachets to 500 mg or 3 sachets to 1000 mg per day).
    In the elderly, it is preferable not to exceed the dose of 2 g of aspirin per day (4 sachets to 500 mg or 2 sachets to 1000 mg per day).
  • Child: 60 mg / kg / day, divided into 4 or 6 doses, ie 15 mg per kg every 6 hours or 10 mg / kg every 4 hours. For information :
    • Child 6 to 8 kg (approximately 3 to 9 months): 1 sachet to 100 mg per dose, to be renewed if necessary after 6 hours, not to exceed 4 sachets per day
    • Child 9 to 11 kg (approximately 9 to 24 months): 1 sachet to 100 mg per dose, to be renewed if necessary after 4 hours, not to exceed 6 sachets per day;
    • Child 12 to 16 kg (approximately 18 months to 5 years): 2 sachets to 100 mg per dose, to be renewed if necessary after 6 hours, not to exceed 8 sachets per day;
    • Children 15 to 20 kg (approximately 3 to 7 years): 1 sachet to 250 mg per dose, to be renewed if necessary after 6 hours, not to exceed 4 sachets per day
    • Child 21-27 kg (approximately 6 to 10 years): 1 sachet at 250 mg per dose, to be renewed if necessary after 4 hours, not to exceed 6 sachets per day;
    • 30 to 40 kg (approximately 9 to 13 years old): 1 sachet to 500 mg, to be renewed if necessary after 6 hours, not to exceed 4 sachets per day;
    • infant from 41 to 50 kg (approximately 13 to 15 years): 1 sachet to 500 mg, to be renewed if necessary after 4 hours, not to exceed 6 sachets per day.
Without medical advice, the duration of treatment should not exceed 3 days in case of fever and 5 days in case of pain.
Rheumatic Pain:
The dosage is 3 to 6 g of aspirin per day in adults and 50 to 100 mg per kg per day in children under medical supervision.
TIPS (summary)
Many drugs contain aspirin or NSAIDs (such as ibuprofen or naproxen); be sure not to take multiple medicines containing these substances simultaneously, as a joint dose may increase the risk of adverse effects.
POSSIBLE ADVERSE EFFECTS (summary)
Gastritis , abdominal pain, bleeding from the nose or gums.
Rare and sometimes serious:
  • hemorrhage of the digestive tract: bloody vomiting, black stools, or more often imperceptible blood loss responsible for the progressive onset of anemia ;
  • allergic: urticaria , edema , asthma .
signs suggesting an overdose : ringing in the ears, sensation of hearing loss, headache.


GLOSSARY (summary)


NSAIDs
Abbreviation for non-steroidal anti-inflammatory drug. Family of anti-inflammatory drugs that are not derived from cortisone (steroids), and the best known of which is aspirin.


allergy
Skin reaction (itching, pimples, swelling) or general discomfort occurring after contact with a particular substance, use of a medication, or ingestion of food. The main forms of allergy are eczema, urticaria, asthma, angioedema and allergic shock (anaphylactic shock). Food allergy can also result in digestive disorders.


anemia
Reduction in the level of hemoglobin in the blood, which usually results in a decrease in the number of red blood cells. Iron is essential for the synthesis of hemoglobin. Iron deficiency during pregnancy, a vegetarian diet, abundant or repeated haemorrhage (menstruation) is a common cause of anemia. Other causes, more rare, are related to vitamin deficiencies of group B.


analgesic
Medication that works against pain. Analgesics act either directly on the centers of pain in the brain or by blocking the transmission of pain to the brain.
Synonym: analgesic.


antecedent
Affection healed or always in evolution. The antecedent may be personal or family. The background is the history of a person's health.


antiplatelet agents
Medication that prevents the platelets from clumping and therefore the clots from forming. The oldest platelet antiaggregant is aspirin taken in small doses.
Anti-aggregants should not be confused with anticoagulants with a different mechanism of action.


anti coagulants
Medication that prevents blood from coagulating and therefore prevents clots from forming in the blood vessels.
Anticoagulants are used to treat or prevent phlebitis, pulmonary embolism, certain infarcts. They also prevent the formation of clots in the heart during rhythm disorders such as atrial fibrillation or in the case of an artificial heart valve.
There are two main types of anticoagulants:
  • oral anticoagulants, which block the action of vitamin K (antivitamin K, or AVK) and whose effectiveness is controlled by a blood test: INR (formerly TP);
  • injectable anticoagulants derived from heparin, the efficacy of which can be controlled by the blood assay of anti-Xa activity, Howell's Time (TH) or Cephalin Kaolin Time (TCK) depending on the products used. A regular dosage of blood platelets is necessary throughout the life of a heparin derivative.


antidepressant
Medication that works against depression. Some antidepressants are also used to combat obsessive-compulsive disorder, generalized anxiety, certain rebellious pain, enuresis, etc.
Depending on their mode of action and adverse effects, antidepressants are divided into different families: imipraminic antidepressants, serotonin reuptake inhibitors, selective or non-selective MAOIs. Finally, other antidepressants do not belong to any of these families, because they possess original properties.
The mode of action of antidepressants has two main aspects: the relief of moral suffering and the fight against inhibition which removes all will to action from the depressed. There may be a time lag between these two effects: moral suffering may persist, while the capacity for action reappears. During this short period, the risk of suicide in some depressed people can be increased. The physician takes it into account in its prescription (possible association with a tranquillizer) and it must imperatively be respected.


antidiabetic
Medicine intended to combat diabetes. There are two categories: oral antidiabetic agents (sulphonylurea, hypoglycaemic and biguanides, mainly) and insulin, which is used only as an injection.


antihypertensive
Medication that fights against excess blood pressure. The main ones are beta-blockers, diuretics, calcium channel blockers, ACE inhibitors, angiotensin II inhibitors and vasodilators.


anti-inflammatory
Medicine that fights against inflammation. It can be either derived from cortisone (steroidal anti-inflammatory), or not derived from cortisone (nonsteroidal anti-inflammatory or NSAID).


antipyretic
Medication used to lower the body temperature during bouts of fever.


asthma
Disease characterized by difficulty breathing, often resulting in wheezing. Asthma, permanent or occurring by crisis, is due to a narrowing and inflammation of the bronchi.


corticoid
Substance close to cortisone. The natural corticoids, necessary for the functioning of the organism, are made by the adrenal glands. Synthetic corticosteroids, chemical derivatives of cortisone, are used as powerful anti-inflammatory drugs.


diuretic
Medication allowing increased kidney water removal. Most often, this loss of water follows the loss of salts caused by the drug (salidiuretic).
Diuretics are mainly used in the treatment of high blood pressure, while their mechanism of action in this disease is poorly understood. They are also prescribed in acute or chronic heart failure, edema and other rarer ailments.
These drugs cause loss of sodium and potassium (except for some of them called "potassium-sparing"). Their prolonged administration therefore requires regular blood potassium control, to avoid heart problems that may result from hypokalemia (lack of potassium in the blood). Lack of sodium is another possible but less frequent consequence of the prolonged use of diuretics; it is also detected by a blood test.


duodenum
A part of the intestine into which food from the stomach penetrates.


G6PD
glucose-6-phosphate dehydrogenase deficiency, an enzyme normally present in the red blood cell. His congenital absence (deficiency) is responsible for a disease called favism; it prohibits the use of certain drugs.


Gastritis
Inflammation of the stomach favored by stress, tobacco, alcohol and certain drugs such as aspirin or anti-inflammatory drugs.


drop
Disease manifested by redness and sharp pain affecting a joint (that of the big toe most often), due to an accumulation of crystals of uric acid.


hemorrhage
Loss of blood from an artery or vein. Hemorrhage can be external, but also internal and go unnoticed.


angiotensin II inhibitors
These drugs are sometimes called sartans, for the names of the molecules belonging to this family end with sartan (losartan, candesartan, etc.).
This family of drugs blocks the action of angiotensin II, a substance that increases blood pressure and tires the heart.
Angiotensin II inhibitors are used to treat high blood pressure.


ACE inhibitors
This family of drugs blocks the action of an enzyme, which converts angiotensin I (naturally inactive substance) to angiotensin II. This last substance increases blood pressure and fatigue the heart.
ACE inhibitors are used to treat high blood pressure, heart failure or myocardial infarction.


heart failure
Inability of the heart to fulfill its function as a pump. The main symptoms of heart failure are fatigue and shortness of breath during an effort.


Hepatic insufficiency
Inability of the liver to perform its function, which is essentially the elimination of some waste, but also the synthesis of many biological substances essential to the body: albumin, cholesterol and coagulation factors (vitamin K, etc.).


renal failure
Inability of the kidneys to eliminate waste or medicinal substances. Advanced renal insufficiency does not necessarily result in a decrease in the amount of urine excreted. Only a blood test and creatinine dosage may reveal this disease.


IRS
Abbreviation for inhibitor of serotonin reuptake. See this term.


edema
Accumulation of water or lymph causing localized swelling.


dosage
Quantity and distribution of the dose of a drug according to the age, weight and general condition of the patient.


salicylates
A family of drugs, the best known of which is acetylsalicylic acid (aspirin).


overdose
Excessive intake of a drug may result in an increase in the intensity of adverse effects or even in the development of specific adverse effects.
This overdose may result from accidental or voluntary poisoning for suicide, so consult your local Poison Control Center (listed in the appendix to the book). However, in most cases, overdose is the result of an error in the understanding of the prescription, or the search for an increase in efficacy by exceeding the recommended dosage. Finally, untimely self-medication may lead to excessive absorption of the same substance contained in different drugs. Some drugs are particularly prone to this risk because they are (wrongly) considered to be harmless: vitamins A and D, aspirin, etc. Stopping or decreasing drug intake helps to remove the disorders associated with an overdose.


ulcer
Injury of skin, mucous membranes or cornea.
  • Leg ulcer: chronic wound due to poor circulation of blood.
  • Gastroduodenal ulcer: a localized wound in the mucosa of the stomach or duodenum due to excess acidity and very often to the presence of a bacterium (Helicobacter pylori). The ulcer is favored by stress, alcohol, smoking and certain medications (aspirin, NSAIDs, etc.).


urticaria
Eruption of pimples on the skin, whose origin is mostly allergic. The buds look like nettles and their color varies from pale pink to red.


virus
A microscopic organism that penetrates the cells of the host, where it reproduces. Much smaller than bacteria, viruses are insensitive to antibiotics. They can sometimes be destroyed by antiviral substances.

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