Dolenio 30 1178MG TABLETS

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Dolenio 1178 mg 30 tablets on sale in our pharmacy bio. Dolenio 1178 mg belongs to a group of medicines called other anti-inflammatory agents and nonsteroidal antirheumatic. This medicine is used to relieve the symptoms of mild to moderate osteoarthritis of the knee.

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Dolenio 30 1178MG TABLETS

 

For warnings, precautions for use and cons-indications, see the instructions for use.


Description Dolenio 1178 mg 30 tablets

 

Dolenio 1178 mg 30 tablets in a group of medicines called other anti-inflammatory agents and non-steroidal anti-rheumatic.
Glucosamine is a natural substance found in the human body, needed synovial fluid and cartilage.
Dolenio is a drug used to relieve the symptoms of mild to moderate osteoarthritis of the knee.
Osteoarthritis is a type of joint degeneration whose symptoms stiffness (after sleep or long rest) and a mobilization to pain (eg, climbing stairs or walking on an uneven surface) that attenuate at rest.

 

Using advice from Dolenio 1178 mg 30 tablets

 

Consult a doctor before starting treatment Dolenio 1178 mg: only a doctor can diagnose osteoarthritis and rule out the presence of joint damage for which it is appropriate to consider another treatment.
The usual dose is one tablet (1178 mg glucosamine) per day for adults.
Dolenio should not be used in children and adolescents under 18 years.
The tablet should be swallowed with some water or other liquid, and can be taken with or without food.
It is possible that the relief of symptoms (especially pain) is felt only after several weeks of treatment, or even more in some cases. If no relief is felt after 2 or 3 months, ask your doctor or pharmacist should be reconsidered because the further processing by Dolenio.

 

Composition Dolenio 1178 mg 30 tablets

 

The active substance is:
One tablet contains 1884.60 mg of glucosamine sulphate stabilized with sodium chloride, corresponding to 1500 mg of glucosamine sulphate or 1178 mg glucosamine.

The other ingredients are:
- Core:
Povidone K30, macrogol 4000, magnesium stearate.
- Coating:
Hypromellose, titanium dioxide (E171), talc, propylene glycol, polysorbate 80.

Important information about some components Dolenio 1178 mg film-coated tablets
One tablet contains 6.52 mmol (151 mg) of sodium.
Please consider this when sodium diet.

 

Precaution of use

 

If you take too many film-coated tablets Dolenio, see your doctor or go to a hospital. A glucosamine overdose can result in headaches, dizziness, confusion, joint pain, nausea, vomiting, diarrhea or constipation. If you develop signs of overdose, stop taking glucosamine.
Do not take a double dose to make up for the dose that you missed.
Do not take Dolenio 1178 mg 30 tablets in the following cases:

- In children and adolescents under 18 years.
- If you are allergic (hypersensitive) to glucosamine or to any of the other ingredients of Dolenio,
- If you are allergic (hypersensitive) to shellfish as the active ingredient, glucosamine, is extracted from them.
- During pregnancy.
- During breastfeeding.

Take special care with Dolenio 1178 mg film-coated tablets:
Consult a physician before taking Dolenio:
- If you have diabetes or glucose intolerance. It is recommended to control your blood sugar before starting treatment and at regular intervals during treatment,
- If you have a known cardiovascular risk factor (eg, hypertension, diabetes, high cholesterol or if you smoke). It is recommended to control your cholesterol before starting treatment, as some cases of hypercholesterolemia have been observed in patients treated with glucosamine,
- If you suffer from asthma. Treatment with glucosamine may worsen symptoms,
- If you suffer from kidney or liver disease, as no studies of glucosamine have been performed in this patient population.

It is particularly important to tell your doctor or pharmacist if you are taking any of the following medications:
- Tetracyclines (antibiotics used against infections)
- Warfarin or similar products (anticoagulants used to prevent thrombosis). The anticoagulant effect may be potentiated by combination with glucosamine. Patients treated with these associations must be monitored with particular attention to the beginning and end of treatment with glucosamine.
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, it is a drug not prescribed.

 

Introducing Dolenio 1178 mg 30 tablets

 

Box of 30 film-coated tablets.

 

Warnings on drugs


Warning, the drug is not a product like any other. Read the package leaflet before ordering. Do not leave medicines within reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Beware of incompatibilities on your current products.

Please tell your online pharmacist of current treatments to identify any incompatibilities. The order confirmation form contains a custom message field provided for this purpose.

Click here to find the manual of this drug on the website of the National Agency of Drug Safety and health products.

Pharmacovigilance Reporting an or effect (s) Adverse (s) bound (s) use of a medicament

VIDAL OF THE FAMILY

Dolenio

Slow Action Antiarthrosis

glucosamine

. Presentations . Composition . Indications . Contraindications . Warning . Drug Interactions . Pregnancy and breastfeeding . Directions for use and dosage . Advice . Undesirable effects . Lexicon

PRESENTATIONS (summary)

DOLENIO: tablet (white with break bar); box of 30.
-

Biocodex Laboratory

COMPOSITION (summary)
p cp
glucosamine 1178 mg
Sodium 151 mg

INDICATIONS (summary)
This drug contains a substance naturally present in cartilage and synovial fluid. It aims to alleviate joint pain and slow the progression of osteoarthritis. Its mechanism of action is not known.
It is used to relieve the symptoms of mild or moderate knee osteoarthritis (pain, mobility).
CONTRAINDICATIONS (summary)
This medicinal product must not be used in case of allergy to crustaceans, the active substance being obtained from crustacean shellfish.
WARNING (Contents)
The analgesic effect of this drug is delayed: it appears after several weeks of treatment. If no effect occurs after 3 months, you should see your doctor again.
Precautions are necessary in case of diabetes , excess cholesterol in the blood or asthma .
This drug contains salt (sodium) in significant quantities.
Dizziness or drowsiness are possible. Make sure you are taking this medication well before driving or operating a hazardous machine.
DRUG INTERACTIONS (summary)
Inform your doctor or pharmacist if you are taking an oral anticoagulant .
PREGNANCY AND BREAST-FEEDING (summary)
The effect of this medication during pregnancy or lactation is not well known: it is not recommended in pregnant or nursing women.
DIRECTIONS FOR USE AND DOSAGE (summary)
This medication can be taken indifferently during or outside meals.

Usual dosage:

  • Adult over 18 years: 1 tablet per day.
TIPS (summary)
In case of osteoarthritis of the knee, it is recommended to fight against possible overweight and to practice a physical activity adapted (swimming, walking ...) to maintain the mobility of the joint.
POSSIBLE ADVERSE EFFECTS (summary)
Common: headache, fatigue, nausea, abdominal pain, difficult digestion, constipation, diarrhea.
Uncommon: rash, itching, hot flush, dizziness, edema .
Also observed were: increased blood cholesterol , worsening asthma , altered blood glucose levels .


GLOSSARY (summary)


allergy
Skin reaction (itching, pimples, swelling) or general discomfort occurring after contact with a particular substance, use of a medication, or ingestion of food. The main forms of allergy are eczema, urticaria, asthma, angioedema and allergic shock (anaphylactic shock). Food allergy can also result in digestive disorders.


analgesic
Medication that works against pain. Analgesics act either directly on the centers of pain in the brain or by blocking the transmission of pain to the brain.
Synonym: analgesic.


anticoagulant
Medication that prevents blood from coagulating and therefore prevents clots from forming in the blood vessels.
Anticoagulants are used to treat or prevent phlebitis, pulmonary embolism, certain infarcts. They also prevent the formation of clots in the heart during rhythm disorders such as atrial fibrillation or in the case of an artificial heart valve.
There are two main types of anticoagulants:
  • oral anticoagulants, which block the action of vitamin K (antivitamin K, or AVK) and whose effectiveness is controlled by a blood test: INR (formerly TP);
  • injectable anticoagulants derived from heparin, the efficacy of which can be controlled by the blood assay of anti-Xa activity, Howell's Time (TH) or Cephalin Kaolin Time (TCK) depending on the products used. A regular dosage of blood platelets is necessary throughout the life of a heparin derivative.


osteoarthritis
Wear of cartilage, responsible for joint pain and limitation of movement.


asthma
Disease characterized by difficulty breathing, often resulting in wheezing. Asthma, permanent or occurring by crisis, is due to a narrowing and inflammation of the bronchi.


cholesterol
Main fat circulating in the blood. It is used in the body as a raw material, especially for the envelope of cells and for the synthesis of steroid hormones. In excess, cholesterol is eliminated in the bile, but it can also accumulate in the arteries and form plaques of atheroma.


diabetes
A general term for diseases that result in the emission of abundant urine and intense thirst. The word diabetes, used alone, is generally related to diabetes mellitus, which corresponds to a disruption in the regulation of the body's sugars by insulin. It results in increased sugar (glucose) in the blood and its possible presence in the urine. There are two types of diabetes mellitus: Type 1 or insulin-dependent diabetes, which requires insulin injections, and type 2 or non-insulin dependent diabetes, which can initially be treated with oral antidiabetics.


glucose
Amount of sugar in one liter of blood. It usually varies between 0.6 and 1.1 g / l (3.3 mmol / l to 6 mmol / l) in the fasted person. The diagnosis of diabetes should be considered when the blood glucose exceeds 1.2 g / l (6.6 mmol / l).


edema
Accumulation of water or lymph causing localized swelling.


salt
Chemical substance of which the best known is sodium chloride, or table salt. The diet salt does not contain sodium; this is generally replaced by potassium.

Cliquez ici pour retrouver la notice de ce médicament sur le site de l'Agence Nationale de Sécurité du Médicament et des produits de santé.

Pharmacovigilance : Déclarer un ou des effet(s) indésirable(s) lié(s) à l'utilisation d'un médicament

NOTICE

ANSM - Last updated: 22/04/2015

Name of the medicinal product

DOLENIO 1178 mg film-coated tablet

glucosamine

framed

Read all of this leaflet carefully before you start taking this medicine.

· Keep this leaflet, you may need to read it again.

· If you have any further questions, ask your doctor or pharmacist.

· This medicine has been prescribed for you. Never give it to anyone else, even if the symptoms are the same, it could be harmful.

· If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

Review summary

In this notice :

1. What is DOLENIO 1178 mg film-coated tablets and when is it used?

2. What should I watch for before taking DOLENIO 1178 mg film-coated tablets ?

3. How to take DOLENIO 1178 mg film-coated tablet ?

4. What are the possible side effects?

5. How to store DOLENIO 1178 mg film-coated tablets?

6. Additional information.

1. WHAT IS DOLENIO 1178 mg film-coated tablet AND WHAT IT IS USED FOR?

Pharmacotherapeutic group

DOLENIO belongs to the group of medicines called other non-steroidal anti-inflammatory and anti-rheumatic agents.

Therapeutic indications

Glucosamine is a naturally occurring substance in the human body that requires synovial fluid and cartilage.

DOLENIO is a medication used to relieve symptoms of mild to moderate osteoarthritis of the knee.

Osteoarthritis is a type of joint degeneration that has as a symptom a stiffness (after sleep or a prolonged rest) and a pain in the mobilization (for example, climbing stairs or walking on an irregular surface) at rest.

2. BEFORE YOU TAKE DOLENIO 1178 mg film-coated tablet?

List of information needed before taking the medication

Consult a physician before starting DOLENIO: only a doctor can diagnose osteoarthritis and prevent the presence of a joint injury for which another treatment should be considered.

Cons-indications

Do not take DOLENIO 1178 mg film-coated tablets in the following cases:

· if you are allergic (hypersensitive) to glucosamine or any of the other ingredients of DOLENIO,

· if you are allergic (hypersensitive) to crustaceans because the active substance, glucosamine, is extracted from them.

DOLENIO should not be used in children younger than 2 years of age.

Precautions for use; special warnings

Take special care with DOLENIO 1178 mg film-coated tablet:

Consult a physician before taking DOLENIO:

· if you have diabetes or glucose intolerance. It is recommended to have your blood glucose checked before starting treatment and at regular intervals during treatment,

· if you have a known cardiovascular risk factor (eg high blood pressure, diabetes, hypercholesterolemia or if you smoke). It is recommended to have your cholesterol checked before starting treatment because some cases of hypercholesterolemia have been observed in patients treated with glucosamine,

· if you have asthma. Treatment with glucosamine may aggravate the symptoms,

· if you have renal or hepatic impairment, as no glucosamine studies have been performed in this patient population.

Interaction with other medicines

Taking other medicines

If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

It is especially important to tell your doctor or pharmacist if you are taking any of the following medications:

· tetracyclines (antibiotics used against infections),

· warfarin or similar products (anticoagulants used to prevent thrombosis). The effect of the anticoagulant may be potentiated by the association with glucosamine. Patients treated with these combinations should therefore be monitored with particular attention to the onset and termination of glucosamine therapy.

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, even if they are a non-prescription medication.

Interactions with food and beverages

Food and drinks

The tablet should be swallowed with a little water, and can be taken during or outside meals.

Interactions with Herbal Medicines or Alternative Therapies

Not applicable.

Use during pregnancy and lactation

Pregnancy

Ask your doctor or pharmacist for advice before taking any medicine.

DOLENIO should not be used during pregnancy.

feeding

Ask your doctor or pharmacist for advice before taking any medicine.

The use of DOLENIO during breast-feeding is not recommended.

Sport

Not applicable.

Effects on ability to drive or use machines

Driving and using machines

No studies have been performed to evaluate the effects of glucosamine on the ability to drive or use machines. If you feel dizzy or drowsy after taking DOLENIO, you should avoid driving a vehicle or using machines.

List of excipients with known effect

Important information about some of the ingredients of DOLENIO 1178 mg film-coated tablet

One tablet contains 6.52 mmol (151 mg) of sodium. Please note this in case of a low-sodium diet.

3. HOW TO TAKE DOLENIO 1178 mg film-coated tablet?

Instructions for proper use

Not applicable.

Dosage, Mode and / or route (s) of administration, Frequency of administration and Duration of treatment

Dosage

Always take the dose recommended by your doctor. If in doubt, consult your doctor or pharmacist.

adults

The usual dose is one tablet (1178 mg glucosamine) per day in adults.

The elderly

No dose adjustment is required.

Patients with renal and / or hepatic impairment

No dosage recommendations can be made because no studies have been performed.

Children and Youth

DOLENIO should not be used in children and adolescents under 18 years of age.

Administration mode

Glucosamine is not indicated for the treatment of acute pain. Symptom relief (especially pain) may be felt only after several weeks of treatment, or even more in some cases. If symptoms are not relieved after 2-3 months, ask your doctor or pharmacist for advice as DOLENIO should be re-evaluated.

Oral use only.

The tablet should be swallowed with a little water or other liquid, and may be taken during or outside meals.

Symptoms and Instructions for Overdose

If you take more DOLENIO 1178 mg film-coated tablets than you should:

If you have taken too many film-coated tablets from DOLENIO, consult your doctor or go to a hospital.

Overdose of glucosamine can lead to headache, dizziness, mental confusion, joint pain, nausea, vomiting, diarrhea or constipation. In case of signs of overdose, stop taking glucosamine.

Instructions for omission of one or more doses

If you forget to take DOLENIO 1178 mg film-coated tablets:

Do not take a double dose to make up for a missed dose.

Risk of withdrawal syndrome

If you stop taking DOLENIO 1178 mg, film-coated tablet:

Your symptoms may recur if you stop taking DOLENIO

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. WHAT ARE POSSIBLE SIDE EFFECTS?

Description of adverse reactions

Like all medicines, DOLENIO 1178 mg film-coated tablets are likely to have side effects, although not everybody gets them.

You should stop taking DOLENIO and consult your doctor immediately if you experience any of the following symptoms: swelling of the face, tongue and / or pharynx and / or difficulty swallowing or hives with difficulty breathing (angioedema).

The following adverse reactions have been reported:

Common side effects (affecting 1 to 10 patients in 100) include headache, fatigue, nausea, abdominal pain, difficult digestion, diarrhea, constipation.

Uncommon side effects (affect 1 to 10 patients in 1,000): skin rash, pruritus and flushing.

Frequency not known (can not be estimated from the available data) : vomiting, urticaria, dizziness, swelling of the feet and ankles, angioedema. Aggravation of preexisting asthma. Deterioration of blood glucose control in diabetic patients.

Cases of hypercholesterolemia have also been reported. It is not possible to determine whether these events were directly related to DOLENIO

DOLENIO may induce elevation of liver enzymes and rarely jaundice.

If you notice any side effects not listed in this leaflet, or if any of the side effects gets serious, contact your doctor or pharmacist.

5. HOW TO STORE DOLENIO 1178 mg film-coated tablet?

Keep out of the reach and sight of children.

Expiration date

Do not use after the expiry date stated on the package.

The expiry date refers to the last day of the month.

Storage conditions

This medicinal product does not require any special storage conditions.

If necessary, warnings against visible signs of deterioration

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist what to do with unused medications. These measures will help protect the environment.

6. ADDITIONAL INFORMATION

Full list of active substances and excipients

What contains DOLENIO 1178 mg film-coated tablet?

The active substance is :

One tablet contains 1884.60 mg of glucosamine sulfate stabilized with sodium chloride, corresponding to 1500 mg of glucosamine sulfate or 1178 mg of glucosamine.

The other components are :

Tablet core

Povidone K30, macrogol 4000, magnesium stearate.

filming

Hypromellose, titanium dioxide (E171), talc, propylene glycol, polysorbate 80.

Pharmaceutical form and content

What is DOLENIO 1178 mg film-coated tablets and contents of the pack?

DOLENIO is in the form of oval, biconvex, white to off-white film-coated tablets with a break-off bar on one side.

The breaking bar is there only to facilitate the fractionation of the tablet for smooth ingestion and not to divide it into two equal doses.

presentations:

20, 30, 60 and 90 film-coated tablets (HDPE) with a screw cap (HDPE).

4, 10, 20, 30, 45, 60 and 90 film-coated tablets (Aluminum / PVC / PVDC).

Not all pack sizes may be marketed.

Name and address of the marketing authorization holder and the holder of the manufacturing authorization responsible for the release of the lots, if different

Holder

BIOCODEX

7 AVENUE GALLIENI

94250 GENTILLY

exploiting

BIOCODEX

7 AVENUE GALLIENI

94250 GENTILLY

Maker

BIOCODEX

7 AVENUE GALLIENI

94250 GENTILLY

or

CENTRAL-PHARMA LIMITED

CAXTON ROAD - BEDFORD

BEDFORDSHIRE MK41 0XZ

UK

Names of the medicinal product in the Member States of the European Economic Area

This medicinal product is authorized in the Member States of the European Economic Area under the following names:

In accordance with the regulations.

Date of approval of the notice

The last date on which this leaflet was approved is {date}.

AMM under exceptional circumstances

Not applicable.

Internet Information

Detailed information on this medicine is available on the Ansm website (France).

Information for health professionals only

Not applicable.

Other

Not applicable.

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Have anti-inflammatory painkillers, anti-pyretic and anti-inflammatory. They often, however, come with side effects, more and more serious in the elderly. Among these side effects, damage of the gastric mucosa, sometimes with bleeding, is one of the most feared. Anti-inflammatory drugs are therefore sometimes associated with gastric protectors or are coated with a special film to being active only in the intestine. In addition, anti-inflammatory often weaken the action of other drugs, such as antihypertensives. Discover our selection of anti inflammatory drugs to your treatment available within the radius pain and fever of your online pharmacy Bio Care and Nature

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