PERMIXON 160 mg composed of Florida palm (Serenoa repens) is indicated for the treatment of moderate voiding disorders associated with benign prostatic hyperplasia in adult men.
For warnings, precautions for use and contraindications, please consult the instructions for use of PERMIXON 160 mg.
Benign prostatic hyperplasia (BPH) - also called prostate adenoma or benign prostatic hyperplasia - usually affects men over 50.
Benign prostatic hyperplasia is characterized by an increase in the size of the prostate. A large prostate compresses the urethra while putting pressure on the bladder, resulting in a frequent urge to urinate and various urination problems , as the case may be (lower and intermittent flow, pain, etc.).
Men with an enlarged prostate have repeated difficulty passing urine. At first, it is difficult for them to start urinating, then, since the urine stream is weak and jerky, they feel like they have never emptied their bladder. In addition, the desire to urinate is felt several times a night. Sometimes patients experience pain in the back and upper thighs.
Permixon 160mg is a drug based on a plant extract with decongestant properties on the urinary tract. Permixon 160mg is recommended in the treatment of certain urination disorders (emission of urine) linked to hypertrophy (increase in volume) of the prostate.
This plant-based medicine contains 160 mg of lipidosterol extract of serenoa repens, more commonly known as Florida palm. These active ingredients produce a decongestant effect on the emission of urine. On the prostate, they reduce the action of the male hormone, a factor that promotes the development of prostate adenomas.
Experimental work, carried out in animals or in vitro on prostate cells, has shown that the lipid-sterolic extract of Serenoa repens:
Therapeutic class Urology nephrology. Treatment of moderate voiding disorders associated with benign prostatic hyperplasia in adult men. (G: genitourinary system and sex hormones)
PERMIXON 160 mg is indicated for the treatment of moderate voiding disorders associated with benign prostatic hyperplasia in adult men.
Adults :
Florida palm ( Serenoa repens (W. Bartram) Small.) (Extracted from the fruit of) …… ............................ .................................................. .......... ……………. 160 mg
Extraction solvent: hexane.
Excipients: Macrogol 10,000. Capsule shell: gelatin, iron oxide yellow, indigotin, titanium dioxide.
Extraction solvent: hexane.
In cases of acute prostatitis, an antibiotic treatment is necessary. We must remain vigilant because prostatitis may in some cases become chronic, causing a reappearance at varying intervals of infections, pain or discomfort.
On the side of symptomatic benign prostate, the treatment aims to improve the quality of life and reduce symptoms by improving urine flow. Many medications are available: alpha blockers, inhibitors of 5-alpha reductase, the herbal products ( infusion-herbal tea Cypress , Arkogélules pumpkin seed oil , Pygeum Africanum - Tadenan and Serenoa repens - Permixon 160 ) , food supplements ( Solgar Prostate Support , Prostaform , Androbiane Pileje ), homeopathic ( Lehning Juniperus Complex L 6 ) and gemmotherapy products ( PRESTAGEM or.
Surgical treatment can be offered in case of failure of medical treatment (10 to 20% of cases) or immediately in case of intense discomfort or complications.
When they cause symptoms, they are particularly troublesome: very frequent urination, difficulty urinating, emptying the bladder, pain, etc. It is therefore important to consult without delay.
Do not take PERMIXON 160 mg, capsule in the following cases:
If you are allergic to the active substance (Florida palm extract) or to any of the other ingredients mentioned in section 6.
Take special care with PERMIXON 160 mg hard capsules:
Permixon 160mg is available in boxes of 60 and 180 capsules.
Be careful, the drug PERMIXON 160 mg is not a product like any other. Read the instructions for the medication carefully before ordering it. Keep medicines out of the reach of children. If symptoms persist, seek the advice of your doctor or pharmacist. Beware of incompatibilities on your current products.
Benign prostatic hyperplasia (BPH) is a noncancerous (benign) enlargement of the prostate that can make it difficult to urinate. The prostate increases in size with age. Men may have difficulty urinating, and have a more frequent and urgent need to urinate.
Benign prostatic hyperplasia (BPH) - also called prostate adenoma or benign prostatic hyperplasia - usually affects men over 50. It results in an increase in the size of the prostate, linked to an adenoma (benign tumor) which most often develops in the part located in contact with the urethra, called the transition zone. Adenoma of the prostate is not cancer. It is a benign disease without major risk for the individual , but which can cause urinary disorders by the pressure exerted on the urethra.
Pharmacovigilance Report an adverse drug reaction(s)
ANSM - Updated on: 25/02/2015
PERMIXON 160 mg capsule
Read this leaflet carefully before you start taking this medicine. It contains important information for your treatment.
If you have any further questions, ask your doctor or pharmacist.
· Keep this leaflet, you may need to read it again.
· If you need more information and advice, ask your pharmacist.
· If symptoms worsen or persist, seek medical attention.
· If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
In this notice :
1. WHAT IS PERMIXON 160 mg capsule AND WHAT IT IS USED FOR?
2. BEFORE YOU TAKE PERMIXON 160 mg capsule?
3. HOW TO TAKE PERMIXON 160 mg capsule?
4. WHAT ARE POSSIBLE SIDE EFFECTS?
5. HOW TO STORE PERMIXON 160 mg capsule?
6. ADDITIONAL INFORMATION
1. WHAT IS PERMIXON 160 mg capsule AND WHAT IT IS USED FOR?
Herbal medicines.
Other drugs used in benign prostatic hypertrophy.
This medication is recommended in the treatment of certain disorders of urination (urine emission) related to hypertrophy (increase in volume) of the prostate.
2. BEFORE YOU TAKE PERMIXON 160 mg capsule?
List of information needed before taking the medication
Not applicable.
Do not take PERMIXON 160 mg capsule in the following cases:
· If you are allergic to the active substance (Florida palm extract) or any of the other ingredients listed in section 6.
Precautions for use; special warnings
Take special care with PERMIXON 160 mg capsule:
· Taking this medication on an empty stomach can sometimes cause nausea.
· During your treatment, your doctor will continue to monitor your prostate regularly. Under no circumstances should PERMIXON 160 mg capsule replace surgery when it is necessary.
Interaction with other medicines
Taking or using other medicines
If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.
Interactions with food and beverages
Not applicable.
Interactions with Herbal Medicines or Alternative Therapies
Not applicable.
Use during pregnancy and lactation
Pregnancy and breast feeding
This medication is not intended for women.
Not applicable.
Effects on ability to drive or use machines
Not applicable.
List of excipients with known effect
Not applicable.
3. HOW TO TAKE PERMIXON 160 mg capsule?
Take the capsules with a glass of water at mealtime.
Dosage
Reserved for adult man.
The usual dose is 2 capsules per day.
Always follow the prescribed dosage.
Administration mode
Oral use.
Frequency of Administration
Not applicable.
Duration of the treatment
The maximum duration of treatment is limited to 6 months.
Symptoms and Instructions for Overdose
If you take more than PERMIXON 160 mg capsule you should:
Passive gastrointestinal disorders (abdominal pain) may occur.
In case of overdose or accidental ingestion: Consult your doctor or pharmacist.
Instructions for omission of one or more doses
If you forget to take PERMIXON 160 mg capsule:
Do not take a double dose to make up for a missed dose.
Not applicable.
4. WHAT ARE POSSIBLE SIDE EFFECTS?
Description of adverse reactions
Like all medicines, PERMIXON 160 mg capsule is likely to have side effects, although not everyone is.
The following side effects may occur:
Common (1 to 10 patients out of 100):
· Headaches (headache),
· Abdominal pain
Uncommon (1 to 10 of 1000 patients):
· Nausea
· An increase in gamma-glutamyltransferases and a moderate increase in transaminases (liver enzymes),
· A skin rash (rash on the skin),
· An abnormal development of the breasts in men (gynecomastia), reversible at the end of treatment.
Frequency not estimable
· Edema (swelling of the skin)
· If you notice any side effects not listed in this leaflet, or if any of the side effects gets serious, tell your doctor or pharmacist
Declaration of side effects
If you experience any side effects, talk to your doctor or pharmacist. This also applies to any side effects not mentioned in this leaflet. You can also report adverse reactions directly via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and network of Regional Centers of Pharmacovigilance - Website: www.ansm.sante.fr
5. HOW TO STORE PERMIXON 160 mg capsule?
Keep out of the reach and sight of children.
Do not use PERMIXON 160 mg capsule after the expiry date which is stated on the carton.
This medication should be stored at a temperature below 30 ° C.
If necessary, warnings against visible signs of deterioration
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist what to do with unused medications. These measures will help protect the environment.
Full list of active substances and excipients
What does PERMIXON 160 mg, capsule contains?
The active substance is:
Palm tree of Florida ( Serenoa repens (W. Bartram) Small) (extract of the fruit of) ............................... 160 mg
Extraction solvent: hexane.
Report drug / excerpt: 7-11: 1.
The other components are:
Macrogol 10,000.
Composition of the capsule shell : gelatin, yellow iron oxide, indigotine, titanium dioxide.
Pharmaceutical form and content
What is PERMIXON 160 mg capsule and contents of the pack?
This medication is in the form of capsules. Box of 30, 56, 60, 100 or 180.
PIERRE FABRE MEDICAMENT
45, PLACE ABEL GANCE
92100 BOULOGNE
PIERRE FABRE MEDICAMENT
45, PLACE ABEL GANCE
92100 BOULOGNE
PIERRE FABRE MEDICAMENT PRODUCTION
45, PLACE ABEL GANCE
92100 BOULOGNE
Names of the medicinal product in the Member States of the European Economic Area
Not applicable.
Date of approval of the notice
The last date on which this leaflet was approved is {date}.
AMM under exceptional circumstances
Not applicable.
Detailed information on this medicine is available on the ANSM website (France).
Information for health professionals only
Not applicable.
Not applicable.
Plant extract
Serenoa repens
. Presentations . Composition . Indications . Warning . Directions for use and dosage . Undesirable effects . Lexicon
PERMIXON: capsule (green); box of 60.
Refunded at 30%. - price: 22,42 euro (s).
PERMIXON: capsule (green); box of 180.
Refunded at 30%. - price: 63,37 euro (s).
Laboratory Pierre Fabre Medicine
p gel | |
Serenoa repens, lipidosteric extract | 160 mg |
Usual dosage:
1 capsule morning and evening.